ATE262522T1 - Benzimidazolverbindungen - Google Patents
BenzimidazolverbindungenInfo
- Publication number
- ATE262522T1 ATE262522T1 AT00944320T AT00944320T ATE262522T1 AT E262522 T1 ATE262522 T1 AT E262522T1 AT 00944320 T AT00944320 T AT 00944320T AT 00944320 T AT00944320 T AT 00944320T AT E262522 T1 ATE262522 T1 AT E262522T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- represented
- alkyl group
- functional
- Prior art date
Links
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- -1 benzimidazole compound Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19335699 | 1999-07-07 | ||
| JP26038499 | 1999-09-14 | ||
| PCT/JP2000/004531 WO2001004110A1 (en) | 1999-07-07 | 2000-07-07 | Benzimidazole compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE262522T1 true ATE262522T1 (de) | 2004-04-15 |
Family
ID=26507825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00944320T ATE262522T1 (de) | 1999-07-07 | 2000-07-07 | Benzimidazolverbindungen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6787561B1 (de) |
| EP (1) | EP1197493B1 (de) |
| JP (1) | JP4624616B2 (de) |
| KR (1) | KR20020022766A (de) |
| AT (1) | ATE262522T1 (de) |
| AU (1) | AU768570B2 (de) |
| CA (1) | CA2378007C (de) |
| DE (1) | DE60009301T2 (de) |
| WO (1) | WO2001004110A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060165605A1 (en) * | 2001-12-28 | 2006-07-27 | Ye-Mon Chen | Process to regenerate fcc spent catalyst |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1250531A (de) * | 1969-01-01 | 1971-10-20 | ||
| US4329347A (en) * | 1978-02-17 | 1982-05-11 | Boehringer Ingelheim Gmbh | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril |
| IT1226100B (it) | 1988-07-07 | 1990-12-10 | Dompe Farmaceutici Spa | Derivati benzimidazolici farmacologicamente attivi. |
| US5387600A (en) | 1992-07-30 | 1995-02-07 | Fuji Photo Film Co., Ltd. | Treating arteriosclerosis using benzimidazole compositions |
| US6376666B1 (en) | 1994-06-10 | 2002-04-23 | Nauchno-Issledovatelsky Institut Farmakologii Rossiiskoi Akademii Meditsinskikh Nauk | 2-mercaptobenzimidazole derivatives possessing pharmacological activity |
| AU6369696A (en) | 1995-07-17 | 1997-02-18 | Fuji Photo Film Co., Ltd. | Benzimidazole compounds |
| JP3781131B2 (ja) * | 1995-07-17 | 2006-05-31 | 富士写真フイルム株式会社 | ベンズイミダゾール化合物 |
| EP0987254B1 (de) * | 1997-05-26 | 2004-12-22 | Kowa Co., Ltd. | Neue zyklische diaminverbindungen und heilmittel das diese enthält |
| JP4402176B2 (ja) | 1997-11-14 | 2010-01-20 | 興和株式会社 | 新規アミド化合物及びこれを含有する医薬 |
| CA2377230C (en) | 1999-06-30 | 2009-06-02 | Kozo Aoki | Benzimidazole compounds and medicaments comprising the same |
-
2000
- 2000-07-07 DE DE60009301T patent/DE60009301T2/de not_active Expired - Lifetime
- 2000-07-07 EP EP00944320A patent/EP1197493B1/de not_active Expired - Lifetime
- 2000-07-07 JP JP2001509720A patent/JP4624616B2/ja not_active Expired - Fee Related
- 2000-07-07 AT AT00944320T patent/ATE262522T1/de not_active IP Right Cessation
- 2000-07-07 US US10/019,668 patent/US6787561B1/en not_active Expired - Fee Related
- 2000-07-07 KR KR1020027000216A patent/KR20020022766A/ko not_active Ceased
- 2000-07-07 WO PCT/JP2000/004531 patent/WO2001004110A1/ja not_active Ceased
- 2000-07-07 CA CA002378007A patent/CA2378007C/en not_active Expired - Fee Related
- 2000-07-07 AU AU58499/00A patent/AU768570B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU768570B2 (en) | 2003-12-18 |
| US6787561B1 (en) | 2004-09-07 |
| EP1197493A1 (de) | 2002-04-17 |
| JP4624616B2 (ja) | 2011-02-02 |
| EP1197493B1 (de) | 2004-03-24 |
| WO2001004110A1 (en) | 2001-01-18 |
| EP1197493A4 (de) | 2003-01-29 |
| KR20020022766A (ko) | 2002-03-27 |
| DE60009301T2 (de) | 2005-02-24 |
| DE60009301D1 (en) | 2004-04-29 |
| AU5849900A (en) | 2001-01-30 |
| CA2378007C (en) | 2006-11-28 |
| CA2378007A1 (en) | 2001-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |