DK0906417T3 - Formuleringer af tværbundne proteinkrystaller og deres anvendelse som katalysatorer i organiske oplösningsmidler - Google Patents

Formuleringer af tværbundne proteinkrystaller og deres anvendelse som katalysatorer i organiske oplösningsmidler

Info

Publication number
DK0906417T3
DK0906417T3 DK97925652T DK97925652T DK0906417T3 DK 0906417 T3 DK0906417 T3 DK 0906417T3 DK 97925652 T DK97925652 T DK 97925652T DK 97925652 T DK97925652 T DK 97925652T DK 0906417 T3 DK0906417 T3 DK 0906417T3
Authority
DK
Denmark
Prior art keywords
catalysts
formulations
cross
organic solvents
linked protein
Prior art date
Application number
DK97925652T
Other languages
Danish (da)
English (en)
Inventor
Nazer K Khalaf
Original Assignee
Altus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altus Pharmaceuticals Inc filed Critical Altus Pharmaceuticals Inc
Application granted granted Critical
Publication of DK0906417T3 publication Critical patent/DK0906417T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK97925652T 1996-05-24 1997-05-20 Formuleringer af tværbundne proteinkrystaller og deres anvendelse som katalysatorer i organiske oplösningsmidler DK0906417T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/652,964 US5932212A (en) 1996-05-24 1996-05-24 Crosslinked protein crystal formulations and their use as catalysts in organic solvents
PCT/US1997/008526 WO1997044445A1 (en) 1996-05-24 1997-05-20 Cross-linked protein crystal formulations and their use as catalysts in organic solvents

Publications (1)

Publication Number Publication Date
DK0906417T3 true DK0906417T3 (da) 2008-07-21

Family

ID=24618946

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97925652T DK0906417T3 (da) 1996-05-24 1997-05-20 Formuleringer af tværbundne proteinkrystaller og deres anvendelse som katalysatorer i organiske oplösningsmidler

Country Status (13)

Country Link
US (2) US5932212A (enExample)
EP (1) EP0906417B1 (enExample)
JP (2) JP4279351B2 (enExample)
KR (1) KR20000015993A (enExample)
AR (1) AR007211A1 (enExample)
AT (1) ATE393216T1 (enExample)
AU (1) AU3072897A (enExample)
DE (1) DE69738648T2 (enExample)
DK (1) DK0906417T3 (enExample)
ID (1) ID17817A (enExample)
IN (1) IN191060B (enExample)
WO (1) WO1997044445A1 (enExample)
ZA (1) ZA974325B (enExample)

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US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
US6350609B1 (en) * 1997-06-20 2002-02-26 New York University Electrospraying for mass fabrication of chips and libraries
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
AU8772498A (en) * 1997-09-05 1999-03-29 Altus Biologics Inc. Carbohydrate crosslinked glycoprotein crystals
US6500933B1 (en) 1997-09-05 2002-12-31 Altus Biologics Inc. Methods of preparing carbohydrate crosslinked glycoprotein crystals
ZA988461B (en) * 1997-09-18 1999-03-30 Idec Pharma Corp Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
AU757991B2 (en) * 1998-04-27 2003-03-13 Altus Pharmaceuticals, Inc. Stabilized protein crystals, formulations containing them and methods of making them
BR9914375A (pt) * 1998-10-09 2001-11-20 Altus Biologics Inc Sistemas heterogêneos para resolução demisturas enantioméricas
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
DE19903125B4 (de) * 1999-01-27 2006-01-05 Sanofi-Aventis Deutschland Gmbh Verfahren zur Trocknung von Kristallen von Insulin oder Insulinanaloga
WO2001012834A1 (en) * 1999-08-18 2001-02-22 Hydrios Biotechnology Oy Process for the preparation and simultaneous separation of enzyme-catalysed products
US7521216B2 (en) 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US20040014195A1 (en) * 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7608445B1 (en) 1999-12-29 2009-10-27 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7300775B2 (en) * 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
EP1292823A1 (en) * 2000-05-23 2003-03-19 Radiometer Medical A/S A sensor membrane, a method for the preparation thereof, a sensor and a layered membrane structure for such sensor
CA2433353C (en) * 2000-12-28 2017-03-21 Altus Biologics, Inc. Crystals of whole antibodies and fragments thereof and methods for making and using them
NZ530700A (en) 2001-06-21 2009-02-28 Altus Pharmaceuticals Inc Spherical protein particles and methods of making and using them
WO2003106415A2 (en) 2002-06-13 2003-12-24 Diversa Corporation Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
US9035123B2 (en) * 2002-10-01 2015-05-19 The Procter & Gamble Company Absorbent article having a lotioned topsheet
NZ571243A (en) * 2002-12-31 2010-04-30 Altus Pharmaceuticals Inc Complexes of protein crystals and ionic polymers comprising human growth hormone and protamine
CA2512052C (en) * 2002-12-31 2016-06-21 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
DE602004023969D1 (de) * 2004-01-01 2009-12-17 Council Scient Ind Res Methode zur herstellung von quervernetzten protein kristallen
SI2198880T1 (sl) * 2004-10-14 2017-02-28 Eli Lilly And Co. Sestavki, ki vsebujejo lipazo, proteazo in amilazo, za zdravljenje pankreasne insuficience
WO2007050100A2 (en) * 2004-11-24 2007-05-03 Industrial Science & Technology Network, Inc. Immobilized enzymes and processes for preparing and using same
US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
GB0513888D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
EP1976551A4 (en) * 2005-12-23 2009-12-30 Altus Pharmaceuticals Inc COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF
WO2008034082A2 (en) * 2006-09-15 2008-03-20 Maroon Biotech, Corporation Method of using amphiphilic multiblock copolymers in food
DK2115153T3 (da) 2007-03-01 2013-09-08 Bp Corp North America Inc Nitrilaser, nucleinsyrer som koder for dem og fremgangsmåder til at fremstille og anvende disse
IL183084A0 (en) * 2007-05-09 2007-09-20 Trans Biodisel Ltd Modified-immobilized enzymes of high tolerance to hydrophilic substrates in organic media
CN101717766B (zh) * 2009-12-01 2012-07-18 暨南大学 蛋白质酶的微水介质固定化方法
EP2588597A4 (en) 2010-06-30 2013-12-25 Codexis Inc CHEMICALLY MODIFIED CARBOHYDRED ANHYDRASES SUITABLE FOR CARBON STORAGE SYSTEMS
JP5740754B2 (ja) * 2010-08-26 2015-07-01 アイシン精機株式会社 酵素結晶固定化電極及び酵素結晶固定化電極の製造方法、並びに酵素結晶固定化電極を備えるバイオ電池及びバイオセンサー

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US4267234A (en) * 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4369226A (en) * 1979-03-19 1983-01-18 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US5152903A (en) * 1988-12-19 1992-10-06 American Cyanamid Company Cross-linked cationic polymeric microparticles
EP0861888B1 (en) * 1990-08-03 2006-04-12 Vertex Pharmaceuticals Incorporated Use of crosslinked crystals as a novel form of enzyme immobilization
GB9309243D0 (en) * 1993-05-05 1993-06-16 Allied Colloids Ltd Enzyme dispersions,their production and compositions containing them
US5773266A (en) * 1993-05-20 1998-06-30 Loders-Croklaan B.V. Immobilized lipases on a dry, porous particulate hydrophobic support and containing a non-ionic surfactant
DE69424683T2 (de) * 1993-12-03 2000-10-05 Buckman Laboratories International, Inc. Enzymstabilisierung durch blockcopolymere
DE4344211A1 (de) * 1993-12-23 1995-06-29 Basf Ag Verfahren zur Erhöhung der Aktivität von hydrolytischen Enzymen

Also Published As

Publication number Publication date
WO1997044445A1 (en) 1997-11-27
JP2008061652A (ja) 2008-03-21
ATE393216T1 (de) 2008-05-15
US5932212A (en) 1999-08-03
ID17817A (id) 1998-01-29
AU3072897A (en) 1997-12-09
EP0906417B1 (en) 2008-04-23
JP2000514282A (ja) 2000-10-31
KR20000015993A (ko) 2000-03-25
DE69738648T2 (de) 2009-05-28
US6042824A (en) 2000-03-28
AR007211A1 (es) 1999-10-13
IN191060B (enExample) 2003-09-13
DE69738648D1 (de) 2008-06-05
ZA974325B (en) 1997-12-18
EP0906417A1 (en) 1999-04-07
JP4279351B2 (ja) 2009-06-17

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