DK0902777T4 - D-mannitol og dets fremstilling - Google Patents

D-mannitol og dets fremstilling

Info

Publication number
DK0902777T4
DK0902777T4 DK97916654T DK97916654T DK0902777T4 DK 0902777 T4 DK0902777 T4 DK 0902777T4 DK 97916654 T DK97916654 T DK 97916654T DK 97916654 T DK97916654 T DK 97916654T DK 0902777 T4 DK0902777 T4 DK 0902777T4
Authority
DK
Denmark
Prior art keywords
mannitol
preparation
excipient
useful
disclosed
Prior art date
Application number
DK97916654T
Other languages
Danish (da)
English (en)
Other versions
DK0902777T3 (da
Inventor
Tomohiro Yoshinari
Fritz Schueckler
Norbert Poellinger
Shinji Maegata
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14109240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0902777(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DK0902777T3 publication Critical patent/DK0902777T3/da
Publication of DK0902777T4 publication Critical patent/DK0902777T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Steroid Compounds (AREA)
DK97916654T 1996-04-16 1997-04-14 D-mannitol og dets fremstilling DK0902777T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9440196 1996-04-16
PCT/JP1997/001286 WO1997038960A1 (en) 1996-04-16 1997-04-14 D-mannitol and its preparation

Publications (2)

Publication Number Publication Date
DK0902777T3 DK0902777T3 (da) 2001-09-24
DK0902777T4 true DK0902777T4 (da) 2004-10-11

Family

ID=14109240

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97916654T DK0902777T4 (da) 1996-04-16 1997-04-14 D-mannitol og dets fremstilling

Country Status (27)

Country Link
US (1) US6503918B2 (zh)
EP (1) EP0902777B2 (zh)
KR (1) KR20000005486A (zh)
CN (1) CN1221398A (zh)
AT (1) ATE202768T1 (zh)
AU (1) AU718658B2 (zh)
BG (1) BG63460B1 (zh)
BR (1) BR9708672A (zh)
CA (1) CA2251092A1 (zh)
CU (1) CU22776A3 (zh)
CZ (1) CZ333698A3 (zh)
DE (1) DE69705516T3 (zh)
DK (1) DK0902777T4 (zh)
EA (1) EA000968B1 (zh)
ES (1) ES2158540T5 (zh)
GR (1) GR3036760T3 (zh)
HU (1) HUP9902165A3 (zh)
ID (1) ID16566A (zh)
IL (1) IL126580A (zh)
NO (2) NO311349B1 (zh)
NZ (1) NZ332313A (zh)
PL (1) PL329614A1 (zh)
PT (1) PT902777E (zh)
SK (1) SK282768B6 (zh)
TR (1) TR199802079T2 (zh)
TW (1) TW515787B (zh)
WO (1) WO1997038960A1 (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10008506A1 (de) * 2000-02-24 2001-09-13 Bayer Ag Verfahren zur Herstellung von pharmazeutischen Darreichungsformen
FR2807034B1 (fr) † 2000-03-29 2002-06-14 Roquette Freres Mannitol pulverulent et son procede de fabrication
AU2001290239A1 (en) * 2000-09-19 2002-04-02 Daiichi Pharmaceutical Co., Ltd. Medicinal composition
US6855333B1 (en) 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
US6979462B1 (en) 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
JP4808960B2 (ja) * 2002-05-14 2011-11-02 エフ エム シー コーポレーション 微結晶質セルロース組成物
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
CA2634232C (en) 2005-12-28 2013-08-20 Takeda Pharmaceutical Company Limited Method of producing solid preparation disintegrating in the oral cavity
KR20080097468A (ko) 2006-02-20 2008-11-05 추가이 세이야쿠 가부시키가이샤 인산 오셀타미비어 함유 의약 조성물
EP2076249A2 (en) * 2006-10-27 2009-07-08 FMC Corporation Dry granulation binders, products, and use thereof
JP5537927B2 (ja) 2007-03-13 2014-07-02 大日本住友製薬株式会社 口腔内崩壊錠
US8389778B2 (en) * 2007-05-22 2013-03-05 Aptuit (West Lafayette), Llc Preparation of mannitol modification III
DE102007052070A1 (de) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Candesartancilexetil
JP2014501226A (ja) 2010-12-17 2014-01-20 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 直接圧縮可能なδ−マンニトールの調製方法
ES2657648T3 (es) 2011-10-05 2018-03-06 Fmc Corporation Composición estabilizadora de celulosa microcristalina y carboximetilcelulosa co-reducida, método para elaborarla y usos
CN103842425B (zh) 2011-10-05 2017-05-24 Fmc有限公司 微晶纤维素和羧甲基纤维素的稳定剂组合物、制备方法和应用
WO2013085810A2 (en) 2011-12-09 2013-06-13 Fmc Corporation Co-attrited stabilizer composition
MX2017000827A (es) * 2014-07-21 2017-05-01 Roquette Freres Composiciones de azucar para la formacion de comprimidos por compresion directa.
IT201900002857A1 (it) 2019-02-27 2020-08-27 Ntc S R L Procedimento di riempimento di contenitori con una polvere
CN113116843A (zh) * 2021-05-11 2021-07-16 福建海西新药创制有限公司 一种含有缬沙坦的药物组合物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
DE3245170A1 (de) 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
FR2571046B1 (fr) 1984-10-03 1987-10-16 Roquette Freres Procede de preparation de mannitol granulaire directement compressible
FR2571045B1 (fr) 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
JPH0653658B2 (ja) 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
NO177005C (no) 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
DE69022861T2 (de) 1989-01-24 1996-04-04 Spi Polyols Inc Kryoschützende kristalline Sorbitolkügelchen.
ATE99545T1 (de) 1989-03-29 1994-01-15 Takeda Chemical Industries Ltd Zusammensetzung mit einer verbindung der vitamin b-gruppe und ihre herstellung.
US5177080A (en) 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
HU9203780D0 (en) * 1991-12-12 1993-03-29 Sandoz Ag Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
FR2710637B1 (fr) † 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
AUPM411494A0 (en) 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation

Also Published As

Publication number Publication date
BG63460B1 (bg) 2002-02-28
EA199800888A1 (ru) 1999-04-29
CU22776A3 (es) 2002-07-24
CA2251092A1 (en) 1997-10-23
HUP9902165A2 (hu) 1999-11-29
WO1997038960A1 (en) 1997-10-23
BG102818A (en) 1999-05-31
GR3036760T3 (en) 2001-12-31
IL126580A (en) 2001-08-08
KR20000005486A (ko) 2000-01-25
NO984803L (no) 1998-12-16
NO311349B1 (no) 2001-11-19
AU718658B2 (en) 2000-04-20
DE69705516D1 (de) 2001-08-09
DE69705516T3 (de) 2004-09-30
HUP9902165A3 (en) 2001-01-29
PT902777E (pt) 2001-11-30
TR199802079T2 (xx) 1999-02-22
US20020107420A1 (en) 2002-08-08
ATE202768T1 (de) 2001-07-15
EP0902777B2 (en) 2004-06-16
NZ332313A (en) 2000-02-28
ID16566A (id) 1997-10-16
EP0902777A1 (en) 1999-03-24
SK143298A3 (en) 1999-04-13
NO20012249L (no) 1998-12-16
BR9708672A (pt) 1999-08-03
DE69705516T2 (de) 2002-04-25
PL329614A1 (en) 1999-03-29
TW515787B (en) 2003-01-01
IL126580A0 (en) 1999-08-17
CZ333698A3 (cs) 1999-01-13
EP0902777B1 (en) 2001-07-04
NO984803D0 (no) 1998-10-15
US6503918B2 (en) 2003-01-07
NO20012249D0 (no) 2001-05-07
SK282768B6 (sk) 2002-12-03
AU2522297A (en) 1997-11-07
ES2158540T3 (es) 2001-09-01
DK0902777T3 (da) 2001-09-24
ES2158540T5 (es) 2004-11-16
EA000968B1 (ru) 2000-08-28
CN1221398A (zh) 1999-06-30

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