DK0896533T3 - Pentafluorbenzensulfonamider og analoger - Google Patents
Pentafluorbenzensulfonamider og analogerInfo
- Publication number
- DK0896533T3 DK0896533T3 DK97907843T DK97907843T DK0896533T3 DK 0896533 T3 DK0896533 T3 DK 0896533T3 DK 97907843 T DK97907843 T DK 97907843T DK 97907843 T DK97907843 T DK 97907843T DK 0896533 T3 DK0896533 T3 DK 0896533T3
- Authority
- DK
- Denmark
- Prior art keywords
- pentafluorobenzene
- sulfonamides
- analogues
- agents
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/49—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60543196A | 1996-02-22 | 1996-02-22 | |
PCT/US1997/002926 WO1997030677A2 (fr) | 1996-02-22 | 1997-02-22 | Pentafluorobenzenesulfonamides et analogues |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0896533T3 true DK0896533T3 (da) | 2004-01-26 |
Family
ID=24423637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97907843T DK0896533T3 (da) | 1996-02-22 | 1997-02-22 | Pentafluorbenzensulfonamider og analoger |
Country Status (13)
Country | Link |
---|---|
US (4) | US5880151A (fr) |
EP (2) | EP0896533B1 (fr) |
JP (1) | JP3421349B2 (fr) |
AT (1) | ATE249213T1 (fr) |
AU (1) | AU711159B2 (fr) |
CA (1) | CA2244785C (fr) |
DE (1) | DE69724777T2 (fr) |
DK (1) | DK0896533T3 (fr) |
EA (1) | EA001367B1 (fr) |
ES (1) | ES2205183T3 (fr) |
NZ (1) | NZ331941A (fr) |
PT (1) | PT896533E (fr) |
WO (1) | WO1997030677A2 (fr) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6613804B2 (en) | 1993-05-20 | 2003-09-02 | Encysive Pharmaceuticals, Inc. | Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin |
CA2244785C (fr) | 1996-02-22 | 2003-12-02 | Tularik, Inc. | Pentafluorobenzenesulfonamides et analogues |
DK0939627T3 (da) | 1996-07-19 | 2003-10-13 | Tularik Inc | Pentaflourbenzensulfonamider og analoger |
HU227183B1 (en) * | 1997-04-28 | 2010-09-28 | Encysive Pharmaceuticals Inc | Sulfonamide derivatives and pharmaceutical compositions containing them for the treatment of endothelin-mediated disorders |
US6583157B2 (en) | 1998-01-29 | 2003-06-24 | Tularik Inc. | Quinolinyl and benzothiazolyl modulators |
EP1053227B1 (fr) | 1998-01-29 | 2008-11-05 | Amgen Inc. | MODULATEURS DU RECEPTEUR ACTIVE DE LA PROLIFERATION DES PEROXYSOMES (PPAR$g(g)) |
EP1090014B1 (fr) | 1998-06-25 | 2003-09-03 | Tularik Inc. | Phosphates d'arylsulfonanilide |
US6153585A (en) | 1998-07-20 | 2000-11-28 | Tularik Inc. | Arylsulfonanilide derivatives |
EP1285911A3 (fr) * | 1998-09-23 | 2003-03-26 | Tularik Inc. | Arylsulfonylanilides-urées |
BR9913903A (pt) * | 1998-09-23 | 2001-07-03 | Tularik Inc | Composto, método para tratar ou impedir um estado doentio, e, composição farmacêutica |
AU731777B2 (en) * | 1998-11-30 | 2001-04-05 | Nihon Nohyaku Co., Ltd. | Aniline derivative and process for producing the same |
US7041691B1 (en) | 1999-06-30 | 2006-05-09 | Amgen Inc. | Compounds for the modulation of PPARγ activity |
PT1206256E (pt) | 1999-07-29 | 2005-09-30 | Amgen Inc | Terapia de combinacao utilizando pentafluorobenzenosulfonamida e compostos de platina |
US6306615B1 (en) | 1999-08-19 | 2001-10-23 | Tularik Inc. | Detection method for monitoring β tubulin isotype specific modification |
WO2001082916A2 (fr) | 2000-05-03 | 2001-11-08 | Tularik Inc. | Compositions therapeutiques combinees et leurs methodes d'utilisation |
US6432427B1 (en) * | 2000-06-30 | 2002-08-13 | Unilever Hope & Personal Care Usa, Division Of Conopco, Inc. | Cosmetic compositions containing substituted sulfonamide derivatives |
US6822001B2 (en) | 2000-11-03 | 2004-11-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
US20050250854A1 (en) * | 2000-11-03 | 2005-11-10 | Amgen Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
JP4171656B2 (ja) | 2001-02-28 | 2008-10-22 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | N−(アリール)−2−アリールエテンスルホンアミド及びその製薬用途 |
US6599866B2 (en) | 2001-04-20 | 2003-07-29 | Exxonmobil Research And Engineering Company | Servo valve erosion inhibited aircraft hydraulic fluids |
EP1403255A4 (fr) | 2001-06-12 | 2005-04-06 | Sumitomo Pharma | Inhibiteurs de rho kinase |
IL163608A0 (en) * | 2002-02-28 | 2005-12-18 | Univ Temple | Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders |
FR2836914B1 (fr) | 2002-03-11 | 2008-03-14 | Aventis Pharma Sa | Indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
US6989399B2 (en) * | 2002-08-01 | 2006-01-24 | Bristol-Myers Squibb Company | Antiamyloid phenylsulfonamides: N-alkanol derivatives |
US7223761B2 (en) | 2003-10-03 | 2007-05-29 | Amgen Inc. | Salts and polymorphs of a potent antidiabetic compound |
WO2006076644A2 (fr) * | 2005-01-14 | 2006-07-20 | Chemocentryx, Inc. | Sulfonamides d'heteroaryle et ccr2 |
US7622583B2 (en) | 2005-01-14 | 2009-11-24 | Chemocentryx, Inc. | Heteroaryl sulfonamides and CCR2 |
FR2884820B1 (fr) * | 2005-04-25 | 2007-07-27 | Merck Sante Soc Par Actions Si | Nouveaux inhibiteurs specifiques de la caspase-10 |
KR101849560B1 (ko) | 2007-07-12 | 2018-04-17 | 케모센트릭스, 인크. | 염증의 치료를 위한 ccr2 조절물질로서 융합된 헤테로아릴 피리딜과 페닐 벤젠술폰아마이드 |
RU2022102328A (ru) | 2016-11-23 | 2022-04-01 | Хемоцентрикс, Инк. | Способ лечения фокально-сегментарного гломерулосклероза |
CN106928101A (zh) * | 2017-03-06 | 2017-07-07 | 中国药科大学 | 苯磺酰胺类ido1抑制剂、其制备方法及应用 |
AU2018347361A1 (en) | 2017-10-11 | 2020-04-30 | Chemocentryx, Inc. | Treatment of focal segmental glomerulosclerosis with CCR2 antagonists |
WO2021099842A1 (fr) * | 2019-11-22 | 2021-05-27 | 2692372 Ontario Inc. | Dérivés de pentafluorobenzènesulfonamide et leurs utilisations |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1955207A (en) * | 1931-09-16 | 1934-04-17 | Ig Farbenindustrie Ag | Mothproofing agent |
US2402623A (en) * | 1943-06-24 | 1946-06-25 | Rohm & Haas | Nu-nitroaryl haloarylsulphonamides |
CH361275A (de) * | 1957-09-10 | 1962-04-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Arylsulfonarylamiden |
GB1242057A (en) * | 1968-07-04 | 1971-08-11 | Ici Ltd | Derivatives of 4-hydroxytetrafluoropyridine and the use thereof as plant growth regulators |
NL174644C (nl) | 1970-04-13 | 1984-07-16 | Minnesota Mining & Mfg | Werkwijze ter bereiding van een herbicide verbinding; tevens werkwijze voor de bereiding van een preparaat met herbicide werking. |
DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
DE3623184A1 (de) * | 1986-07-10 | 1988-01-14 | Kali Chemie Ag | Verfahren zur herstellung von n-fluorsulfonamiden |
DE3632329A1 (de) * | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
US4883914A (en) * | 1987-08-17 | 1989-11-28 | American Cyanamid Company | Benzenesulfonyl carboxamide compounds useful as herbicidal agents |
DE3804990A1 (de) * | 1988-02-18 | 1989-08-31 | Basf Ag | Herbizid wirksame, heterocyclisch substituierte sulfonamide |
FR2645537B1 (fr) | 1989-04-05 | 1994-03-04 | Fabre Medicament Pierre | Nouveaux sulfonamides derives d'acides benzocycliques ou benzoheterocycliques, leur preparation et leur application en therapeutique |
FR2665440B1 (fr) | 1990-07-31 | 1994-02-04 | Lipha | Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant. |
US5189211A (en) * | 1990-08-01 | 1993-02-23 | Taisho Pharmaceutical Co., Ltd. | Sulfonamide derivatives |
ATE167473T1 (de) * | 1990-08-20 | 1998-07-15 | Eisai Co Ltd | Sulfonamid-derivate |
CH681529A5 (fr) | 1990-08-21 | 1993-04-15 | Alusuisse Lonza Services Ag | |
AU2546595A (en) * | 1994-05-25 | 1995-12-18 | Dow Chemical Company, The | Sulfonamides useful as lubricants in magnetic recording media |
AU6112896A (en) | 1995-06-07 | 1996-12-30 | Sugen, Inc. | Tyrphostin-like compounds for the treatment of cell prolifer ative disorders or cell differentiation disorders |
CA2244785C (fr) | 1996-02-22 | 2003-12-02 | Tularik, Inc. | Pentafluorobenzenesulfonamides et analogues |
DK0939627T3 (da) * | 1996-07-19 | 2003-10-13 | Tularik Inc | Pentaflourbenzensulfonamider og analoger |
US5773236A (en) * | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
US6284923B1 (en) * | 1997-08-22 | 2001-09-04 | Tularik Inc | Substituted benzene compounds as antiproliferative and cholesterol lowering action |
AU1208999A (en) | 1997-11-10 | 1999-05-31 | Array Biopharma, Inc. | Compounds which inhibit tryptase activity |
EP1090014B1 (fr) * | 1998-06-25 | 2003-09-03 | Tularik Inc. | Phosphates d'arylsulfonanilide |
US6153585A (en) * | 1998-07-20 | 2000-11-28 | Tularik Inc. | Arylsulfonanilide derivatives |
PT1206256E (pt) * | 1999-07-29 | 2005-09-30 | Amgen Inc | Terapia de combinacao utilizando pentafluorobenzenosulfonamida e compostos de platina |
US6822001B2 (en) * | 2000-11-03 | 2004-11-23 | Tularik Inc. | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents |
-
1997
- 1997-02-22 CA CA002244785A patent/CA2244785C/fr not_active Expired - Fee Related
- 1997-02-22 EP EP97907843A patent/EP0896533B1/fr not_active Expired - Lifetime
- 1997-02-22 JP JP53039797A patent/JP3421349B2/ja not_active Expired - Fee Related
- 1997-02-22 EP EP03009125A patent/EP1334719A3/fr not_active Withdrawn
- 1997-02-22 AT AT97907843T patent/ATE249213T1/de not_active IP Right Cessation
- 1997-02-22 WO PCT/US1997/002926 patent/WO1997030677A2/fr active IP Right Grant
- 1997-02-22 PT PT97907843T patent/PT896533E/pt unknown
- 1997-02-22 DK DK97907843T patent/DK0896533T3/da active
- 1997-02-22 DE DE69724777T patent/DE69724777T2/de not_active Expired - Lifetime
- 1997-02-22 ES ES97907843T patent/ES2205183T3/es not_active Expired - Lifetime
- 1997-02-22 EA EA199800752A patent/EA001367B1/ru unknown
- 1997-02-22 NZ NZ331941A patent/NZ331941A/xx unknown
- 1997-02-22 AU AU19739/97A patent/AU711159B2/en not_active Ceased
- 1997-07-18 US US08/896,827 patent/US5880151A/en not_active Expired - Lifetime
-
1999
- 1999-01-06 US US09/227,216 patent/US6121304A/en not_active Expired - Fee Related
-
2000
- 2000-08-07 US US09/633,740 patent/US6316484B1/en not_active Expired - Fee Related
-
2001
- 2001-10-05 US US09/972,743 patent/US7138418B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1997030677A2 (fr) | 1997-08-28 |
US6121304A (en) | 2000-09-19 |
US5880151A (en) | 1999-03-09 |
EP0896533B1 (fr) | 2003-09-10 |
CA2244785A1 (fr) | 1997-08-28 |
WO1997030677A3 (fr) | 1997-11-20 |
JP3421349B2 (ja) | 2003-06-30 |
US6316484B1 (en) | 2001-11-13 |
EP0896533A2 (fr) | 1999-02-17 |
DE69724777D1 (de) | 2003-10-16 |
EA001367B1 (ru) | 2001-02-26 |
NZ331941A (en) | 2000-04-28 |
DE69724777T2 (de) | 2004-07-15 |
ATE249213T1 (de) | 2003-09-15 |
AU711159B2 (en) | 1999-10-07 |
EP1334719A2 (fr) | 2003-08-13 |
PT896533E (pt) | 2004-02-27 |
ES2205183T3 (es) | 2004-05-01 |
EA199800752A1 (ru) | 1999-04-29 |
AU1973997A (en) | 1997-09-10 |
CA2244785C (fr) | 2003-12-02 |
US20020143036A1 (en) | 2002-10-03 |
JP2000505459A (ja) | 2000-05-09 |
EP1334719A3 (fr) | 2003-09-24 |
US7138418B2 (en) | 2006-11-21 |
EP0896533A4 (fr) | 1999-04-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0896533T3 (da) | Pentafluorbenzensulfonamider og analoger | |
NO2022019I1 (no) | Eribulin eller et farmasøytisk akseptabelt salt derav - forlenget SPC | |
DK0939627T3 (da) | Pentaflourbenzensulfonamider og analoger | |
HUP0101999A2 (hu) | 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása | |
DE60009511D1 (de) | Nematizide trifluorbutene | |
DE60143984D1 (de) | Neue phenylalanin-derivate | |
BR9811099A (pt) | Inibidores de urocinase | |
DE60121461D1 (de) | Kondensierte pyridoindolderivate | |
FI920023A0 (fi) | Heteroarylpiperazinfoereningar som antipsykotiska aemnen. | |
TR200002542T2 (tr) | Meta-azasiklik amino benzoik asit bileşikleri ve bunların integrin antagonistleri olan türevleri | |
NO20023977D0 (no) | 8,8A-dihydro-indeno(1,2-D)tiazolderivater med en sulfonamid- eller sulfon substituert i 2-posisjonen, en fremgangsmåte forfremstilling derav og anvendelse som et legemiddel | |
EA200100516A1 (ru) | Производные 3,3-биарилпиперидина и 2,2-биарилморфолина | |
YU44301A (sh) | 5ht1 antagonisti za antidepresantnu terapiju | |
DK1250337T3 (da) | Substituerede homopiperidinylbenzimidazol-analoger som fundus-relaksanter | |
EA200100711A1 (ru) | Аналоги нуклеозида (варианты) и их применение, комбинация и способ лечения вирусных инфекций, фармацевтическая композиция | |
ES2168355T3 (es) | Derivados de bisulfuro de indano-2-mercaptoacetilamida utiles como inhibidores de la encefalinasa. | |
DK0420224T3 (da) | Anthihepatopatisk middel | |
ES2123728T3 (es) | Derivados de pirrolo-pirazina de actividad 5-ht3. | |
DK0520372T3 (da) | Inositol-phosphat-analoger som calciumantagonistiske stoffer | |
EA200001157A2 (ru) | Новые замещенные производные (дигидро)бензоксазина и (дигидро)бензотиазина, способ их получения и содержащие их фармацевтические композиции | |
HUP0002727A2 (hu) | Eljárás fibrinogén csökkentésére benzotiofénszármazékok felhasználásával | |
BR9915898A (pt) | Compostos, composição farmacêutica, e, utilização de um composto | |
ATE268768T1 (de) | Antithrombosemittel | |
PT1140932E (pt) | Derivados de 1,8-benzonaftiridina | |
MX9204755A (es) | Derivados de 3-amido pirazol y composiciones farmaceuticas que los contienen. |