DK0888336T3 - Nye substituerede N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)-piperidin-1-yl)-1-(aryl)butyl)benzamider til behandling af allergisygdomme - Google Patents
Nye substituerede N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)-piperidin-1-yl)-1-(aryl)butyl)benzamider til behandling af allergisygdommeInfo
- Publication number
- DK0888336T3 DK0888336T3 DK97905689T DK97905689T DK0888336T3 DK 0888336 T3 DK0888336 T3 DK 0888336T3 DK 97905689 T DK97905689 T DK 97905689T DK 97905689 T DK97905689 T DK 97905689T DK 0888336 T3 DK0888336 T3 DK 0888336T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzamides
- benzimidazol
- piperidin
- aryl
- butyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60421696A | 1996-02-21 | 1996-02-21 | |
| US08/778,996 US5922737A (en) | 1996-02-21 | 1997-01-06 | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
| PCT/US1997/001571 WO1997030989A1 (en) | 1996-02-21 | 1997-01-29 | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl-amino)piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0888336T3 true DK0888336T3 (da) | 2002-12-02 |
Family
ID=27084615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97905689T DK0888336T3 (da) | 1996-02-21 | 1997-01-29 | Nye substituerede N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)-piperidin-1-yl)-1-(aryl)butyl)benzamider til behandling af allergisygdomme |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0888336B1 (da) |
| JP (1) | JP2001504798A (da) |
| KR (1) | KR19990087131A (da) |
| CN (1) | CN1115341C (da) |
| AR (1) | AR005896A1 (da) |
| AT (1) | ATE221882T1 (da) |
| AU (1) | AU710488B2 (da) |
| BR (1) | BR9707652A (da) |
| CA (1) | CA2247105C (da) |
| DE (1) | DE69714579T2 (da) |
| DK (1) | DK0888336T3 (da) |
| ES (1) | ES2176687T3 (da) |
| HK (1) | HK1019734A1 (da) |
| HU (1) | HUP9901030A3 (da) |
| IL (1) | IL125578A (da) |
| NO (1) | NO983830L (da) |
| NZ (1) | NZ330908A (da) |
| PT (1) | PT888336E (da) |
| TW (1) | TW562804B (da) |
| WO (1) | WO1997030989A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| GB0315203D0 (en) * | 2003-06-28 | 2003-08-06 | Celltech R&D Ltd | Chemical compounds |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| CN1067385C (zh) * | 1994-08-25 | 2001-06-20 | 默里尔药物公司 | 用于治疗变应性疾病的新的取代的哌啶类化合物 |
-
1997
- 1997-01-29 DK DK97905689T patent/DK0888336T3/da active
- 1997-01-29 CA CA002247105A patent/CA2247105C/en not_active Expired - Fee Related
- 1997-01-29 NZ NZ330908A patent/NZ330908A/en unknown
- 1997-01-29 BR BR9707652A patent/BR9707652A/pt not_active IP Right Cessation
- 1997-01-29 ES ES97905689T patent/ES2176687T3/es not_active Expired - Lifetime
- 1997-01-29 PT PT97905689T patent/PT888336E/pt unknown
- 1997-01-29 JP JP53016697A patent/JP2001504798A/ja not_active Abandoned
- 1997-01-29 IL IL12557897A patent/IL125578A/en not_active IP Right Cessation
- 1997-01-29 AU AU22519/97A patent/AU710488B2/en not_active Ceased
- 1997-01-29 HU HU9901030A patent/HUP9901030A3/hu unknown
- 1997-01-29 EP EP97905689A patent/EP0888336B1/en not_active Expired - Lifetime
- 1997-01-29 KR KR1019980706522A patent/KR19990087131A/ko active IP Right Grant
- 1997-01-29 CN CN97192390A patent/CN1115341C/zh not_active Expired - Fee Related
- 1997-01-29 AT AT97905689T patent/ATE221882T1/de not_active IP Right Cessation
- 1997-01-29 DE DE69714579T patent/DE69714579T2/de not_active Expired - Fee Related
- 1997-01-29 WO PCT/US1997/001571 patent/WO1997030989A1/en not_active Application Discontinuation
- 1997-02-18 TW TW086101887A patent/TW562804B/zh not_active IP Right Cessation
- 1997-02-19 AR ARP970100645A patent/AR005896A1/es not_active Application Discontinuation
-
1998
- 1998-08-20 NO NO983830A patent/NO983830L/no not_active Application Discontinuation
-
1999
- 1999-07-07 HK HK99102910A patent/HK1019734A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO983830L (no) | 1998-10-20 |
| AU2251997A (en) | 1997-09-10 |
| EP0888336B1 (en) | 2002-08-07 |
| CN1211246A (zh) | 1999-03-17 |
| JP2001504798A (ja) | 2001-04-10 |
| ES2176687T3 (es) | 2002-12-01 |
| HK1019734A1 (en) | 2000-02-25 |
| CA2247105C (en) | 2002-05-14 |
| EP0888336A1 (en) | 1999-01-07 |
| IL125578A0 (en) | 1999-03-12 |
| TW562804B (en) | 2003-11-21 |
| CN1115341C (zh) | 2003-07-23 |
| CA2247105A1 (en) | 1997-08-28 |
| HUP9901030A3 (en) | 2002-01-28 |
| HUP9901030A2 (hu) | 1999-07-28 |
| AU710488B2 (en) | 1999-09-23 |
| BR9707652A (pt) | 1999-07-27 |
| NZ330908A (en) | 2001-04-27 |
| PT888336E (pt) | 2002-12-31 |
| WO1997030989A1 (en) | 1997-08-28 |
| ATE221882T1 (de) | 2002-08-15 |
| NO983830D0 (no) | 1998-08-20 |
| DE69714579D1 (de) | 2002-09-12 |
| DE69714579T2 (de) | 2003-04-10 |
| KR19990087131A (ko) | 1999-12-15 |
| AR005896A1 (es) | 1999-07-21 |
| IL125578A (en) | 2002-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE250605T1 (de) | Piperidin verbindung zur behandlung von psoriasis | |
| DK1140915T3 (da) | 4-(aminomethyl)-piperidinbenzamider til behandling af gastrointestinale forstyrrelser | |
| DE60300021D1 (de) | (S)-4-Amino-5-Chloro-2-Methoxy-N-[1-[1-(2-Tetrahydrofuryl-Carbonyl)-4-Piperidinylmethyl]-4-Piperidinyl]benzamid zur Behandlung von Magen-Darmbewegungskrankheiten | |
| DE60023873D1 (de) | Mittel zur behandlung von erkrankungen der speiseröhre | |
| NO20014960L (no) | Nye fremgangsmåter for behandling | |
| DK1478358T3 (da) | Sorafenibtosylat til behandling af sygdomme kendetegnet ved unormal angiogenese | |
| DK1223925T3 (da) | Fedtsyrederivat til behandling af eksterne sekretionslidelser | |
| DE60133921D1 (de) | Verwendung von rosuvastatin (zd-4522) zur behandlung von heterozygoter familiärer hypercholesterolämie | |
| DE69620306D1 (de) | 4-(.Alpha.-hydroxy-.alpha.-aryl-alkylcarbonylamino)-Piperidine zur Behandlung und Prophylaxe von Erkrankungen der Harnwege | |
| DE60234760D1 (de) | Phenylindole zur behandlung von hiv | |
| DK1165510T3 (da) | 1-arensulfonyl-2-aryl-pyrrolidin- og -piperidinderivater til behandling af CNS-lidelser | |
| NO20033433D0 (no) | Fremgangsmåte for fremstilling av 2-(2-pyridylmetyl)sulfinyl- 1H-benzimidasol | |
| DE60130661D1 (de) | Verwendung der 13-cis retinsäure zur behandlung von emphysemen | |
| DE69737067D1 (de) | Vakzine zur behandlung von mycosen | |
| DK0983275T3 (da) | Nye triptolidderivater, der er nyttige til behandling af autoimmune sygdomme | |
| DE50105735D1 (de) | Chlorzoxazon zur behandlung von psoriasis | |
| DK0888336T3 (da) | Nye substituerede N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)-piperidin-1-yl)-1-(aryl)butyl)benzamider til behandling af allergisygdomme | |
| ATE390134T1 (de) | (+)-alpha-(2,3-dimethoxyphenyl)-1-(2-(4- fluorophenyl)ethyl)-4-piperidinemethanol oder prodrug davon zur behandlung von demenzsymptomen oder kognitiven störungen | |
| DK0888114T3 (da) | Anvendelse af (+)-alfa-(2,3-dimethoxyphenyl)-1-[2-(4-flourphenyl)-ethyl]-4-piperidinmethanol til behandling af depressive lidelser og bipolare lidelser | |
| DK0874843T3 (da) | Substituerede 4-(1H-benzimidazol-2-yl)(1,4)diazepaner, der er nyttige til behandling af allergisygdomme | |
| DK1200447T3 (da) | Oxazinocarbazoler til behandling af CNS-sygdomme | |
| DK0854146T3 (da) | Substitueret 4-(6-fluor-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridin til behandling af CNS forstyrrelser | |
| DK1095035T3 (da) | Fremgangsmåde til fremstilling af 4-(3-pyridinyl)-1H-imidazol og de anvendte mellemprodukter | |
| ATE300531T1 (de) | Isonipecotamide zur behandlung von integrin vermittelten störungen | |
| DE69731620D1 (de) | Neue substituierte n-methyl-n-(4-(4-(1h-benzimidazol-2-yl) (1,4)diazepan-1-yl)-2-(aryl)butyl)benzamide zur behandlung von allergischen krankheiten |