DK0885222T3 - Heterocycliske ergolinderivater som 5HT1A-receptorligander - Google Patents

Heterocycliske ergolinderivater som 5HT1A-receptorligander

Info

Publication number
DK0885222T3
DK0885222T3 DK97903245T DK97903245T DK0885222T3 DK 0885222 T3 DK0885222 T3 DK 0885222T3 DK 97903245 T DK97903245 T DK 97903245T DK 97903245 T DK97903245 T DK 97903245T DK 0885222 T3 DK0885222 T3 DK 0885222T3
Authority
DK
Denmark
Prior art keywords
heterocyclic
receptor ligands
ergoline derivatives
5ht1a receptor
5ht1a
Prior art date
Application number
DK97903245T
Other languages
English (en)
Inventor
Sergio Mantegani
Tiziano Bandiera
Maurizio Meroni
Mario Varasi
Carla Caccia
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Application granted granted Critical
Publication of DK0885222T3 publication Critical patent/DK0885222T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97903245T 1996-02-15 1997-02-07 Heterocycliske ergolinderivater som 5HT1A-receptorligander DK0885222T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603226.3A GB9603226D0 (en) 1996-02-15 1996-02-15 Heterocyclyl-ergoline derivatives
PCT/EP1997/000582 WO1997030050A1 (en) 1996-02-15 1997-02-07 Heterocyclyl-ergoline derivatives as 5-ht1a receptor ligands

Publications (1)

Publication Number Publication Date
DK0885222T3 true DK0885222T3 (da) 2001-08-27

Family

ID=10788832

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97903245T DK0885222T3 (da) 1996-02-15 1997-02-07 Heterocycliske ergolinderivater som 5HT1A-receptorligander

Country Status (26)

Country Link
US (1) US6087371A (da)
EP (1) EP0885222B1 (da)
JP (1) JP2000504700A (da)
KR (1) KR19990082680A (da)
CN (1) CN1211253A (da)
AR (1) AR005820A1 (da)
AT (1) ATE201683T1 (da)
AU (1) AU1767797A (da)
BR (1) BR9707463A (da)
CA (1) CA2243992A1 (da)
DE (1) DE69705032T2 (da)
DK (1) DK0885222T3 (da)
EA (1) EA199800720A1 (da)
ES (1) ES2159838T3 (da)
GB (1) GB9603226D0 (da)
GR (1) GR3036390T3 (da)
HU (1) HUP9900572A3 (da)
IL (1) IL125344A0 (da)
MX (1) MX9806341A (da)
NO (1) NO983656L (da)
NZ (1) NZ331087A (da)
PL (1) PL328373A1 (da)
PT (1) PT885222E (da)
TW (1) TW360655B (da)
WO (1) WO1997030050A1 (da)
ZA (1) ZA971167B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1685838A1 (en) * 2000-08-16 2006-08-02 Pharmacia & Upjohn Company LLC Compounds for the treatment of addictive disorders
NZ524741A (en) * 2000-08-16 2005-01-28 Upjohn Co Heterocyclic amines, phenylazacycloalkanes, cabergoline and aromatic bicyclic amines for the treatment of alcohol, nicotine and drug addiction
US8106074B2 (en) 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence
ES2618022T3 (es) * 2008-07-17 2017-06-20 Bayer Cropscience Ag Compuestos heterocíclicos como pesticidas
CN106866656A (zh) * 2017-02-28 2017-06-20 西南交通大学 一类麦角碱衍生物及其在预防和治疗精神疾病的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU39278B (en) * 1976-12-22 1984-10-31 Lek Tovarna Farmacevtskih Process for preparing 5-bromo nicotinic acid esters
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
AU553809B2 (en) * 1981-07-21 1986-07-31 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
HU190105B (en) * 1983-06-03 1986-08-28 Gyogyszerkutato Intezet Process for production of pirazolyl-methyl-ergolin- derivatives and their acid additional salts
HU193781B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof
GB8612366D0 (en) * 1986-05-21 1986-06-25 Erba Farmitalia Ergoline esters
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
ES2032570T3 (es) * 1987-11-20 1993-02-16 Farmitalia Carlo Erba S.R.L. Derivados antiparkinson de ergolina. (reserva del art. 167.2 cpe).
JPH04504582A (ja) * 1990-01-25 1992-08-13 フアルミタリア・カルロ・エルバ・エツセ・エルレ・エルレ エルゴリン誘導体を製造する方法
JP2888648B2 (ja) * 1990-12-28 1999-05-10 出光興産株式会社 スチレン系重合体の製造方法及びその触媒

Also Published As

Publication number Publication date
IL125344A0 (en) 1999-03-12
BR9707463A (pt) 1999-07-20
ES2159838T3 (es) 2001-10-16
NZ331087A (en) 1999-08-30
TW360655B (en) 1999-06-11
HUP9900572A3 (en) 2000-10-30
ZA971167B (en) 1997-08-25
EP0885222B1 (en) 2001-05-30
AR005820A1 (es) 1999-07-14
GR3036390T3 (en) 2001-11-30
PT885222E (pt) 2001-10-31
WO1997030050A1 (en) 1997-08-21
CN1211253A (zh) 1999-03-17
DE69705032D1 (de) 2001-07-05
CA2243992A1 (en) 1997-08-21
PL328373A1 (en) 1999-01-18
US6087371A (en) 2000-07-11
JP2000504700A (ja) 2000-04-18
AU1767797A (en) 1997-09-02
HUP9900572A2 (hu) 1999-06-28
GB9603226D0 (en) 1996-04-17
NO983656L (no) 1998-10-12
EP0885222A1 (en) 1998-12-23
ATE201683T1 (de) 2001-06-15
MX9806341A (es) 1998-10-31
NO983656D0 (no) 1998-08-10
EA199800720A1 (ru) 1999-02-25
KR19990082680A (ko) 1999-11-25
DE69705032T2 (de) 2001-11-22

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