DK0882726T3 - Carbazolcarboxamider som 5-HT1F-agonister - Google Patents
Carbazolcarboxamider som 5-HT1F-agonisterInfo
- Publication number
- DK0882726T3 DK0882726T3 DK98304343T DK98304343T DK0882726T3 DK 0882726 T3 DK0882726 T3 DK 0882726T3 DK 98304343 T DK98304343 T DK 98304343T DK 98304343 T DK98304343 T DK 98304343T DK 0882726 T3 DK0882726 T3 DK 0882726T3
- Authority
- DK
- Denmark
- Prior art keywords
- carboxamides
- carbazole
- ht1f agonists
- ht1f
- agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polyamides (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Organic Insulating Materials (AREA)
- Conductive Materials (AREA)
- Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
- Semiconductor Integrated Circuits (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4858497P | 1997-06-04 | 1997-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0882726T3 true DK0882726T3 (da) | 2003-09-22 |
Family
ID=21955349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98304343T DK0882726T3 (da) | 1997-06-04 | 1998-06-02 | Carbazolcarboxamider som 5-HT1F-agonister |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0882726B1 (no) |
| JP (1) | JP2002502419A (no) |
| KR (1) | KR20010013409A (no) |
| CN (1) | CN1259049A (no) |
| AT (1) | ATE240953T1 (no) |
| AU (1) | AU729786B2 (no) |
| BR (1) | BR9810610A (no) |
| CA (1) | CA2291624A1 (no) |
| DE (1) | DE69814735T2 (no) |
| DK (1) | DK0882726T3 (no) |
| EA (1) | EA001718B1 (no) |
| ES (1) | ES2199410T3 (no) |
| HU (1) | HUP0004142A3 (no) |
| ID (1) | ID23053A (no) |
| IL (1) | IL133279A0 (no) |
| NO (1) | NO995963L (no) |
| NZ (1) | NZ501569A (no) |
| PL (1) | PL337221A1 (no) |
| PT (1) | PT882726E (no) |
| TR (1) | TR199903014T2 (no) |
| WO (1) | WO1998055115A1 (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000034266A1 (en) * | 1998-12-11 | 2000-06-15 | Eli Lilly And Company | Indole derivatives and their use as 5-ht1f agonists |
| EP1184373A4 (en) | 1999-04-20 | 2004-10-20 | Meiji Seika Kaisha | TRICYCLIC CONNECTIONS |
| AU779034B2 (en) | 1999-08-04 | 2005-01-06 | Icagen, Inc. | Benzanilides as potassium channel openers |
| US6495550B2 (en) | 1999-08-04 | 2002-12-17 | Icagen, Inc. | Pyridine-substituted benzanilides as potassium ion channel openers |
| BR0012934A (pt) * | 1999-08-04 | 2003-07-29 | Icagen Inc | Processos para a redução de dor e de ansiedade |
| TWI263497B (en) | 2002-03-29 | 2006-10-11 | Lilly Co Eli | Pyridinoylpiperidines as 5-HT1F agonists |
| US7608629B2 (en) | 2003-04-18 | 2009-10-27 | Eli Lilly And Company | (Piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-HT1F agonists |
| UA82711C2 (en) | 2003-09-12 | 2008-05-12 | Эли Лилли Энд Компани | Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists |
| EP1697305B1 (en) | 2003-12-17 | 2007-08-15 | Eli Lilly And Company | Substituted (4-aminocyclohexen-1-yl)phenyl and (4-aminocyclohexen-1-yl)pyridinyl compounds as 5-ht1f agonists |
| JP5092746B2 (ja) | 2005-08-08 | 2012-12-05 | アステラス製薬株式会社 | アシルグアニジン誘導体またはその塩 |
| CA2677995A1 (en) * | 2007-02-07 | 2008-08-14 | Astellas Pharma Inc. | Acylguanidine derivative |
| RU2562255C2 (ru) * | 2010-03-22 | 2015-09-10 | Актелион Фармасьютиклз Лтд | Производные 3-(гетероариламино)-1,2,3,4-тетрагидро-9н-карбазола и их применение в качестве модуляторов рецепторов простагландина d2 |
| WO2011123654A1 (en) | 2010-04-02 | 2011-10-06 | Colucid Pharmaceuticals, Inc. | Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists |
| JP2016516761A (ja) * | 2013-04-09 | 2016-06-09 | クレスセット バイオモレキュラー ディスカバリー リミテッド | 炎症性眼疾患の局所治療 |
| TWI776175B (zh) | 2019-07-09 | 2022-09-01 | 美商美國禮來大藥廠 | 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體，以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備 |
| CN112125836A (zh) * | 2020-10-15 | 2020-12-25 | 濮阳惠成电子材料股份有限公司 | 有机电致光电材料中间体n-苯基咔唑-3-羧酸乙酯的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9226566D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
| WO1996029075A1 (en) * | 1995-03-20 | 1996-09-26 | Eli Lilly And Company | 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists |
| EP0749962B1 (en) * | 1995-06-23 | 2000-11-02 | Eli Lilly And Company | 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta(7,6-B)indoles |
-
1998
- 1998-01-06 ID IDW991411A patent/ID23053A/id unknown
- 1998-06-01 WO PCT/US1998/003340 patent/WO1998055115A1/en not_active Application Discontinuation
- 1998-06-01 CA CA002291624A patent/CA2291624A1/en not_active Abandoned
- 1998-06-01 KR KR19997011410A patent/KR20010013409A/ko not_active Application Discontinuation
- 1998-06-01 BR BR9810610-4A patent/BR9810610A/pt not_active IP Right Cessation
- 1998-06-01 EA EA199901113A patent/EA001718B1/ru not_active IP Right Cessation
- 1998-06-01 NZ NZ501569A patent/NZ501569A/en unknown
- 1998-06-01 PL PL98337221A patent/PL337221A1/xx unknown
- 1998-06-01 TR TR1999/03014T patent/TR199903014T2/xx unknown
- 1998-06-01 HU HU0004142A patent/HUP0004142A3/hu unknown
- 1998-06-01 JP JP50237299A patent/JP2002502419A/ja not_active Ceased
- 1998-06-01 AU AU77955/98A patent/AU729786B2/en not_active Ceased
- 1998-06-01 IL IL13327998A patent/IL133279A0/xx unknown
- 1998-06-01 CN CN98805776A patent/CN1259049A/zh active Pending
- 1998-06-02 ES ES98304343T patent/ES2199410T3/es not_active Expired - Lifetime
- 1998-06-02 EP EP98304343A patent/EP0882726B1/en not_active Expired - Lifetime
- 1998-06-02 AT AT98304343T patent/ATE240953T1/de not_active IP Right Cessation
- 1998-06-02 DK DK98304343T patent/DK0882726T3/da active
- 1998-06-02 PT PT98304343T patent/PT882726E/pt unknown
- 1998-06-02 DE DE69814735T patent/DE69814735T2/de not_active Expired - Fee Related
-
1999
- 1999-12-03 NO NO995963A patent/NO995963L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ID23053A (id) | 2000-01-20 |
| HUP0004142A2 (hu) | 2001-05-28 |
| HUP0004142A3 (en) | 2002-10-28 |
| PT882726E (pt) | 2003-09-30 |
| EP0882726A1 (en) | 1998-12-09 |
| ATE240953T1 (de) | 2003-06-15 |
| PL337221A1 (en) | 2000-08-14 |
| DE69814735T2 (de) | 2004-03-25 |
| AU7795598A (en) | 1998-12-21 |
| CA2291624A1 (en) | 1998-12-10 |
| NZ501569A (en) | 2001-11-30 |
| EA199901113A1 (ru) | 2000-08-28 |
| WO1998055115A1 (en) | 1998-12-10 |
| EA001718B1 (ru) | 2001-08-27 |
| JP2002502419A (ja) | 2002-01-22 |
| KR20010013409A (ko) | 2001-02-26 |
| NO995963D0 (no) | 1999-12-03 |
| TR199903014T2 (xx) | 2000-05-22 |
| AU729786B2 (en) | 2001-02-08 |
| DE69814735D1 (de) | 2003-06-26 |
| IL133279A0 (en) | 2001-04-30 |
| NO995963L (no) | 1999-12-03 |
| BR9810610A (pt) | 2000-09-12 |
| EP0882726B1 (en) | 2003-05-21 |
| CN1259049A (zh) | 2000-07-05 |
| ES2199410T3 (es) | 2004-02-16 |
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