DK0876394T3 - Fremstilling af (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazol-3,20-dion - Google Patents
Fremstilling af (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazol-3,20-dionInfo
- Publication number
- DK0876394T3 DK0876394T3 DK96942323T DK96942323T DK0876394T3 DK 0876394 T3 DK0876394 T3 DK 0876394T3 DK 96942323 T DK96942323 T DK 96942323T DK 96942323 T DK96942323 T DK 96942323T DK 0876394 T3 DK0876394 T3 DK 0876394T3
- Authority
- DK
- Denmark
- Prior art keywords
- dieno
- pregna
- oxazole
- dione
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0068—Nitrogen and oxygen at position 16(17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95119626 | 1995-12-13 | ||
PCT/EP1996/005390 WO1997021722A1 (en) | 1995-12-13 | 1996-12-04 | PREPARATION OF (11β,16β)-21-(ACETYLOXY)-11-HYDROXY-2'-METHYL-5'H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0876394T3 true DK0876394T3 (da) | 2001-08-06 |
Family
ID=8219882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96942323T DK0876394T3 (da) | 1995-12-13 | 1996-12-04 | Fremstilling af (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazol-3,20-dion |
Country Status (16)
Country | Link |
---|---|
US (1) | US6103895A (ja) |
EP (1) | EP0876394B1 (ja) |
JP (1) | JP4016070B2 (ja) |
KR (1) | KR100453029B1 (ja) |
CN (1) | CN100358914C (ja) |
AT (1) | ATE201213T1 (ja) |
AU (1) | AU707409B2 (ja) |
CA (1) | CA2238691C (ja) |
DE (1) | DE69612871T2 (ja) |
DK (1) | DK0876394T3 (ja) |
ES (1) | ES2157476T3 (ja) |
GR (1) | GR3035988T3 (ja) |
HK (1) | HK1017691A1 (ja) |
PT (1) | PT876394E (ja) |
WO (1) | WO1997021722A1 (ja) |
ZA (1) | ZA9610412B (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT879242E (pt) * | 1995-12-13 | 2000-10-31 | Lepetit Spa | Preparacao de (11beta,16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dieno¬17,16-d|oxazole-3,20-diona |
CN106008660B (zh) * | 2016-06-20 | 2018-02-23 | 湖南科瑞生物制药股份有限公司 | 地夫可特的制备方法 |
CN107488203B (zh) * | 2017-08-30 | 2019-06-04 | 湖南科瑞生物制药股份有限公司 | 一种16a-羟基泼尼松龙的制备方法 |
EP4230196A1 (en) | 2022-02-21 | 2023-08-23 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of dystrophinopathies |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE250538C (ja) * | ||||
DD250538A1 (de) * | 1984-12-11 | 1987-10-14 | Jenapharm Veb | Verfahren zur selektiven acetylierung von hydroxy-steroidcarbonsaeuren |
GB8730216D0 (en) * | 1987-12-29 | 1988-02-03 | Lepetit Spa | Process for preparation of pregnenooxazolines |
PT879242E (pt) * | 1995-12-13 | 2000-10-31 | Lepetit Spa | Preparacao de (11beta,16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dieno¬17,16-d|oxazole-3,20-diona |
-
1996
- 1996-12-04 CA CA002238691A patent/CA2238691C/en not_active Expired - Fee Related
- 1996-12-04 JP JP52169797A patent/JP4016070B2/ja not_active Expired - Lifetime
- 1996-12-04 ES ES96942323T patent/ES2157476T3/es not_active Expired - Lifetime
- 1996-12-04 CN CNB961990139A patent/CN100358914C/zh not_active Expired - Lifetime
- 1996-12-04 KR KR10-1998-0704320A patent/KR100453029B1/ko not_active IP Right Cessation
- 1996-12-04 EP EP96942323A patent/EP0876394B1/en not_active Expired - Lifetime
- 1996-12-04 DK DK96942323T patent/DK0876394T3/da active
- 1996-12-04 WO PCT/EP1996/005390 patent/WO1997021722A1/en active IP Right Grant
- 1996-12-04 DE DE69612871T patent/DE69612871T2/de not_active Expired - Lifetime
- 1996-12-04 AU AU11756/97A patent/AU707409B2/en not_active Expired
- 1996-12-04 US US09/077,728 patent/US6103895A/en not_active Expired - Lifetime
- 1996-12-04 AT AT96942323T patent/ATE201213T1/de active
- 1996-12-04 PT PT96942323T patent/PT876394E/pt unknown
- 1996-12-11 ZA ZA9610412A patent/ZA9610412B/xx unknown
-
1999
- 1999-06-29 HK HK99102753A patent/HK1017691A1/xx not_active IP Right Cessation
-
2001
- 2001-05-31 GR GR20010400839T patent/GR3035988T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU1175697A (en) | 1997-07-03 |
PT876394E (pt) | 2001-08-30 |
ATE201213T1 (de) | 2001-06-15 |
JP2000503632A (ja) | 2000-03-28 |
JP4016070B2 (ja) | 2007-12-05 |
CN100358914C (zh) | 2008-01-02 |
WO1997021722A1 (en) | 1997-06-19 |
ZA9610412B (en) | 1997-07-23 |
DE69612871D1 (de) | 2001-06-21 |
EP0876394A1 (en) | 1998-11-11 |
KR19990072026A (ko) | 1999-09-27 |
CA2238691C (en) | 2004-07-20 |
US6103895A (en) | 2000-08-15 |
KR100453029B1 (ko) | 2004-12-17 |
ES2157476T3 (es) | 2001-08-16 |
GR3035988T3 (en) | 2001-08-31 |
AU707409B2 (en) | 1999-07-08 |
DE69612871T2 (de) | 2001-10-04 |
EP0876394B1 (en) | 2001-05-16 |
HK1017691A1 (en) | 1999-11-26 |
CN1204339A (zh) | 1999-01-06 |
CA2238691A1 (en) | 1997-06-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY2009010I2 (el) | Μεθοδος για εμπλουτισμο r-επιμερους 16,17-ακεταλης παραγωγων των 21-ακυλοξυ πρεγνα-1,4-διεν-11.βητα., 16.αλφα., 17.αλφα.-τριολ-3,20-διονης | |
DE122005000030I1 (de) | Pregna-1, 4-dien-3, 20-dion-16-17-acetal-21-ester,Verfahren zur Herstellung, sowie diese enthaltendepharmazeutische Pr{parate. | |
ATE166577T1 (de) | Glykosylierte steroid derivate für den transport durch biologische membranen und verfahren zu deren herstellung | |
ES2132249T3 (es) | Procedimiento de preparacion de pregnanos 3-alfa-hidroxi,3-beta sustituidos. | |
GEP20012530B (en) | Neuroactive Steroids of the Androstane and Pregnane Series | |
DK0876394T3 (da) | Fremstilling af (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazol-3,20-dion | |
PT78743A (de) | 1-alkyl-androsta-1,4-dien-3,17-dione verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate | |
CA2394731A1 (en) | Process for preparing 17alpha-acetoxy-11beta-[4-n,n-(dimethylamino)phenyl]-21-methoxy-19-norpregna-4,9-diene-3,20-dione, intermediates useful in the process, and processes for preparing such intermediates | |
DK0923599T3 (da) | Fremgangsmåde til fremstilling af 17-estere af 9alfa, 21-dihalogenpregnan-11beta, 17alfa-diol-20-oner | |
ATE1710T1 (de) | Verfahren zur herstellung von chenodeoxycholsaeure und zwischenprodukte dazu. | |
DE69310052T2 (de) | Kardioaktive 17B-(3-Furyl) und 17B-(4-Pyridazinyl)-5beta, 14beta-Androstan Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon | |
NO20031964D0 (no) | Fremgangsmåte for fremstilling av 16,17- [(cykloheksylmetylen)bis(oksy)]-11,21-dihydroksy-pregna-1,4-dien-3,20-dion eller dets 21-isobutyratved transketalisering | |
NO982413L (no) | Fremstilling av (11<beta>, 16<beta>)-21-(3-karboksy-3-oksypropoksy)-11-hydroksy-2'-metyl-5'H-pregna-1,4-dieno£17,16-d|oksazol-3,20-dion | |
HUT64365A (en) | Process for steroid aromatase inhibitors containing 2-beta, 19-methylene-amino bridge and pharmaceutical preparatives containing them | |
Cooley et al. | 802. Modified steroid hormones. Part XXIII. Some pentacyclic types | |
ATE73136T1 (de) | Verfahren zur herstellung von 6alpha, 9alphadifluor-11beta, 17alpha-dihydroxy-16alpha-methyl4-pregnen-3,20-dion und dessen derivate. | |
Vernon et al. | C-3 glucosiduronates of metabolites of adrenal steroids | |
EP0136465A3 (en) | Process for the preparation of 17-alpha-acetoxy-1-alpha, 2-alpha-methylene-pregna-4,6-diene-3,20 dione | |
岩井重久 | A Note on “Anaerobic Digestion and Utilization of Digester Gas” | |
DK0885240T3 (da) | Fremgangsmåde til rensning af 11beta-21-dihydroxy-2' -methyl-5'betaH-pregna-1, 4-dieno[17,16-d] oxazol-3,20-dion | |
GB1082679A (en) | Process for the manufacture of a-nor-b-homo-steroids and steroid intermediates therefor | |
DK0879242T3 (da) | Fremstilling af (11alpha, 16alpha)-21-(3-carboxy-3-oxopropoxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno(17,16-d)oxazol-3,2 |