ZA9610412B - Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'-H-pregna-1,4-dieno [17, 16-d]oxazole-3,20-dione - Google Patents

Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'-H-pregna-1,4-dieno [17, 16-d]oxazole-3,20-dione

Info

Publication number
ZA9610412B
ZA9610412B ZA9610412A ZA9610412A ZA9610412B ZA 9610412 B ZA9610412 B ZA 9610412B ZA 9610412 A ZA9610412 A ZA 9610412A ZA 9610412 A ZA9610412 A ZA 9610412A ZA 9610412 B ZA9610412 B ZA 9610412B
Authority
ZA
South Africa
Prior art keywords
dieno
pregna
oxazole
dione
methyl
Prior art date
Application number
ZA9610412A
Other languages
English (en)
Inventor
Luigi Forte
Calogero Cancellieri
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of ZA9610412B publication Critical patent/ZA9610412B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA9610412A 1995-12-13 1996-12-11 Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'-H-pregna-1,4-dieno [17, 16-d]oxazole-3,20-dione ZA9610412B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95119626 1995-12-13

Publications (1)

Publication Number Publication Date
ZA9610412B true ZA9610412B (en) 1997-07-23

Family

ID=8219882

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9610412A ZA9610412B (en) 1995-12-13 1996-12-11 Preparation of (11beta, 16beta)-21-(acetyloxy)-11-hydroxy-2'-methyl-5'-H-pregna-1,4-dieno [17, 16-d]oxazole-3,20-dione

Country Status (16)

Country Link
US (1) US6103895A (ja)
EP (1) EP0876394B1 (ja)
JP (1) JP4016070B2 (ja)
KR (1) KR100453029B1 (ja)
CN (1) CN100358914C (ja)
AT (1) ATE201213T1 (ja)
AU (1) AU707409B2 (ja)
CA (1) CA2238691C (ja)
DE (1) DE69612871T2 (ja)
DK (1) DK0876394T3 (ja)
ES (1) ES2157476T3 (ja)
GR (1) GR3035988T3 (ja)
HK (1) HK1017691A1 (ja)
PT (1) PT876394E (ja)
WO (1) WO1997021722A1 (ja)
ZA (1) ZA9610412B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT879242E (pt) * 1995-12-13 2000-10-31 Lepetit Spa Preparacao de (11beta,16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dieno¬17,16-d|oxazole-3,20-diona
CN106008660B (zh) * 2016-06-20 2018-02-23 湖南科瑞生物制药股份有限公司 地夫可特的制备方法
CN107488203B (zh) * 2017-08-30 2019-06-04 湖南科瑞生物制药股份有限公司 一种16a-羟基泼尼松龙的制备方法
EP4230196A1 (en) 2022-02-21 2023-08-23 Som Innovation Biotech, S.A. Compounds for use in the treatment of dystrophinopathies

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE250538C (ja) *
DD250538A1 (de) * 1984-12-11 1987-10-14 Jenapharm Veb Verfahren zur selektiven acetylierung von hydroxy-steroidcarbonsaeuren
GB8730216D0 (en) * 1987-12-29 1988-02-03 Lepetit Spa Process for preparation of pregnenooxazolines
PT879242E (pt) * 1995-12-13 2000-10-31 Lepetit Spa Preparacao de (11beta,16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dieno¬17,16-d|oxazole-3,20-diona

Also Published As

Publication number Publication date
AU1175697A (en) 1997-07-03
PT876394E (pt) 2001-08-30
ATE201213T1 (de) 2001-06-15
DK0876394T3 (da) 2001-08-06
JP2000503632A (ja) 2000-03-28
JP4016070B2 (ja) 2007-12-05
CN100358914C (zh) 2008-01-02
WO1997021722A1 (en) 1997-06-19
DE69612871D1 (de) 2001-06-21
EP0876394A1 (en) 1998-11-11
KR19990072026A (ko) 1999-09-27
CA2238691C (en) 2004-07-20
US6103895A (en) 2000-08-15
KR100453029B1 (ko) 2004-12-17
ES2157476T3 (es) 2001-08-16
GR3035988T3 (en) 2001-08-31
AU707409B2 (en) 1999-07-08
DE69612871T2 (de) 2001-10-04
EP0876394B1 (en) 2001-05-16
HK1017691A1 (en) 1999-11-26
CN1204339A (zh) 1999-01-06
CA2238691A1 (en) 1997-06-19

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