DK0850062T3 - Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker - Google Patents

Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker

Info

Publication number
DK0850062T3
DK0850062T3 DK96928874T DK96928874T DK0850062T3 DK 0850062 T3 DK0850062 T3 DK 0850062T3 DK 96928874 T DK96928874 T DK 96928874T DK 96928874 T DK96928874 T DK 96928874T DK 0850062 T3 DK0850062 T3 DK 0850062T3
Authority
DK
Denmark
Prior art keywords
halofuginone
humans
drug
manufacture
treatment
Prior art date
Application number
DK96928874T
Other languages
Danish (da)
English (en)
Inventor
Israel Vlodavsky
Aron Nagler
Shimon Slavin
Mark Pines
Original Assignee
Agricultural Res Org
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricultural Res Org, Hadasit Med Res Service filed Critical Agricultural Res Org
Application granted granted Critical
Publication of DK0850062T3 publication Critical patent/DK0850062T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK96928874T 1995-08-15 1996-08-12 Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker DK0850062T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11495195A IL114951A (en) 1995-08-15 1995-08-15 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization
PCT/US1996/013210 WO1997006805A1 (en) 1995-08-15 1996-08-12 Quinazolinone-containing pharmaceutical compositions for prevention of neovascularization and for treating human malignancies

Publications (1)

Publication Number Publication Date
DK0850062T3 true DK0850062T3 (da) 2005-02-07

Family

ID=11067877

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96928874T DK0850062T3 (da) 1995-08-15 1996-08-12 Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker

Country Status (11)

Country Link
EP (1) EP0850062B1 (ja)
JP (1) JP4101875B2 (ja)
CN (1) CN1113652C (ja)
AT (1) ATE279925T1 (ja)
AU (1) AU705955B2 (ja)
CA (1) CA2228524C (ja)
DE (1) DE69633673T2 (ja)
DK (1) DK0850062T3 (ja)
ES (1) ES2231824T3 (ja)
IL (1) IL114951A (ja)
WO (1) WO1997006805A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0944382A1 (en) 1996-09-30 1999-09-29 Brigham & Women's Hospital Methods and compounds for treatment of abnormal uterine bleeding
US6028075A (en) * 1997-02-11 2000-02-22 Pines; Mark Quinazolinone containing pharmaceutical compositions for prevention of neovascularization and for treating malignancies
IT1316986B1 (it) 2000-01-25 2003-05-26 Sigma Tau Ind Farmaceuti Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
IL147416A (en) * 2001-12-31 2008-11-26 Israel State Combined modalities for improved cancer treatment
CN100434425C (zh) * 2005-03-09 2008-11-19 首都师范大学 4-喹唑啉酮衍生物及其在抗肿瘤药物中的应用
CN102653521B (zh) * 2012-04-27 2014-08-06 首都师范大学 吲哚-2-酮的哌嗪硫代甲酰肼衍生物及其制备方法和用途
AR110963A1 (es) 2017-02-07 2019-05-22 Dae Woong Pharma Compuestos heterocíclicos, su método de preparación y composición farmacéutica que los comprende

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3320124A (en) * 1964-07-20 1967-05-16 American Cyanamid Co Method for treating coccidiosis with quinazolinones
DE2934069A1 (de) * 1979-08-23 1981-03-12 Hoechst Ag, 6000 Frankfurt Mittel gegen theileriosen und seine verwendung.
DE3638446A1 (de) * 1986-11-11 1988-05-26 Hoechst Ag Coccidiozide mittel
CA2113229C (en) * 1994-01-11 1999-04-20 Mark Pines Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof
IL110831A (en) * 1994-08-31 1998-12-27 Hadasit Med Res Service Pharmaceutical compositions containing quinazolinone derivatives for preventing restenosis
IL112125A (en) * 1994-12-22 1998-02-08 Hadasit Med Res Service Quinazolinone-containing pharmaceutical compositions

Also Published As

Publication number Publication date
AU705955B2 (en) 1999-06-03
JPH11511172A (ja) 1999-09-28
JP4101875B2 (ja) 2008-06-18
IL114951A0 (en) 1995-12-08
CN1194583A (zh) 1998-09-30
EP0850062A4 (en) 2000-03-15
DE69633673D1 (de) 2004-11-25
IL114951A (en) 1999-08-17
EP0850062A1 (en) 1998-07-01
AU6846996A (en) 1997-03-12
DE69633673T2 (de) 2006-02-09
EP0850062B1 (en) 2004-10-20
CN1113652C (zh) 2003-07-09
CA2228524A1 (en) 1997-02-27
ES2231824T3 (es) 2005-05-16
CA2228524C (en) 2003-01-07
WO1997006805A1 (en) 1997-02-27
ATE279925T1 (de) 2004-11-15

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