DK0840621T3 - - Google Patents

Info

Publication number
DK0840621T3
DK0840621T3 DK96928368T DK96928368T DK0840621T3 DK 0840621 T3 DK0840621 T3 DK 0840621T3 DK 96928368 T DK96928368 T DK 96928368T DK 96928368 T DK96928368 T DK 96928368T DK 0840621 T3 DK0840621 T3 DK 0840621T3
Authority
DK
Denmark
Prior art keywords
gestagen
oestrogen
ethoxyethoxy
tts
androgen
Prior art date
Application number
DK96928368T
Other languages
English (en)
Inventor
Guenter Cordes
Martin Siegmund
Original Assignee
Labtec Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labtec Gmbh filed Critical Labtec Gmbh
Application granted granted Critical
Publication of DK0840621T3 publication Critical patent/DK0840621T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
DK96928368T 1995-07-22 1996-07-22 DK0840621T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19526864A DE19526864A1 (de) 1995-07-22 1995-07-22 Hormonpflaster
PCT/EP1996/003229 WO1997003698A1 (de) 1995-07-22 1996-07-22 Hormonpflaster

Publications (1)

Publication Number Publication Date
DK0840621T3 true DK0840621T3 (da) 2002-04-15

Family

ID=7767564

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96928368T DK0840621T3 (da) 1995-07-22 1996-07-22

Country Status (21)

Country Link
US (1) US5985311A (da)
EP (1) EP0840621B1 (da)
JP (1) JPH11504038A (da)
KR (1) KR19990035795A (da)
CN (1) CN1195994A (da)
AT (1) ATE212234T1 (da)
AU (1) AU6786696A (da)
BR (1) BR9609794A (da)
CA (1) CA2227538A1 (da)
CZ (1) CZ20498A3 (da)
DE (3) DE19526864A1 (da)
DK (1) DK0840621T3 (da)
ES (1) ES2171710T3 (da)
HU (1) HUP9900301A3 (da)
MX (1) MX9800469A (da)
NO (1) NO980277D0 (da)
NZ (1) NZ316026A (da)
PL (1) PL324552A1 (da)
PT (1) PT840621E (da)
SK (1) SK8198A3 (da)
WO (1) WO1997003698A1 (da)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050276836A1 (en) * 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
DE19728516C2 (de) * 1997-07-04 1999-11-11 Sanol Arznei Schwarz Gmbh TTS zur Verabreichung von Levonorgestrel und gegebenenfalls Estradiol
FR2779062A1 (fr) * 1998-06-02 1999-12-03 Investigations Therapeutiques Preparation sous forme galenique simple visant a limiter les effets induits durant la menopause et posterieurement et traitement avec cette preparation
DE19901085C2 (de) * 1999-01-14 2003-12-18 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einer selbstklebenden Matrix, enthaltend organische Säure-Additionssalze von Alkaloiden des Morphin- bzw. Morphinantyps
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
EP1216699A1 (de) * 2000-12-21 2002-06-26 Schering Aktiengesellschaft Transdermalsystem enthaltend ein hochpotentes Gestagen
US8728445B2 (en) 2001-05-01 2014-05-20 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Sciences Hydrogel Compositions
DE60239528D1 (de) 2001-05-01 2011-05-05 Corium International Redwood City Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
KR20030028253A (ko) * 2001-09-27 2003-04-08 (주)지씨아이 잔탄검과 알긴을 이용한 항고지단백혈증 경피투과제제의제조
JP5027373B2 (ja) * 2002-08-09 2012-09-19 帝國製薬株式会社 エストラジオール含有貼付剤
JP4919573B2 (ja) * 2002-08-09 2012-04-18 帝國製薬株式会社 ノルエチステロン含有外用貼付剤
US8124122B2 (en) 2002-08-09 2012-02-28 Teikoku Seiyaku Co., Ltd. Female hormone-containing patch
KR20040037653A (ko) * 2002-10-29 2004-05-07 대한민국(경북대학교 총장) 갈변 방지제
JO2492B1 (en) 2003-04-28 2009-10-05 شيرينج ايه جي A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients
CN1929819B (zh) 2004-01-30 2012-02-29 考里安国际公司 递送活性剂的快速溶解膜
RU2393877C2 (ru) 2004-08-05 2010-07-10 Кориум Интернэшнл, Инк. Адгезивная композиция
WO2006036899A2 (en) * 2004-09-27 2006-04-06 Corium International, Inc. Transdermal systems for the delivery of estrogens and progestins
US20080089925A1 (en) * 2004-11-10 2008-04-17 Masato Wakamatsu Drug for External Use and Adhesive Patch
ES2389630T3 (es) * 2004-11-10 2012-10-29 Hisamitsu Pharmaceutical Co., Inc. Fármacos para uso externo y parche adhesivo
ATE509969T1 (de) * 2005-09-23 2011-06-15 Nat Starch Chem Invest Klebstoffe auf acrylpolymerbasis
US20070141132A1 (en) * 2005-11-02 2007-06-21 Hagit Sacks Human growth hormone patch formulations
WO2008091588A1 (en) 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
EP2187969A2 (en) * 2007-08-17 2010-05-26 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
WO2010019953A1 (en) 2008-08-15 2010-02-18 Arcion Therapeutics, Inc. High concentration local anesthetic formulations for treating non-neuropathic pain
DE102008059054A1 (de) 2008-11-26 2010-05-27 Otto Bock Pur Life Science Gmbh Polyurethanpflaster für die transdermale Applikation von Wirkstoffen und Verfahren zu dessen Herstellung
US8784879B2 (en) 2009-01-14 2014-07-22 Corium International, Inc. Transdermal administration of tamsulosin
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PL2782584T3 (pl) 2011-11-23 2021-12-13 Therapeuticsmd, Inc. Naturalne skojarzone hormonalne formulacje i terapie zastępcze
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10206932B2 (en) 2014-05-22 2019-02-19 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PL3372229T3 (pl) 2014-06-06 2021-10-04 Ovid Therapeutics, Inc. Sposoby zwiększenia hamowania tonicznego i leczenia zespołu angelmana
WO2016018993A1 (en) 2014-07-29 2016-02-04 Therapeuticsmd, Inc. Transdermal cream
JP2018520189A (ja) 2015-07-17 2018-07-26 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics, Inc. ガボキサドールでの発達障害の処置方法
US9682069B2 (en) 2015-07-17 2017-06-20 Ovid Therapeutics Inc Methods of treating Dravet syndrome
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US10660967B2 (en) 2016-10-21 2020-05-26 Augusta University Research Institute, Inc. Curcumin conjugates and methods of use thereof
US10071083B2 (en) 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US10953036B2 (en) 2017-11-20 2021-03-23 University Of Georgia Research Foundation, Inc. Compositions and methods of modulating HIF-2A to improve muscle generation and repair
WO2019152808A1 (en) 2018-02-01 2019-08-08 Yale University Compositions and methods for inhibition of nuclear-penetrating antibodies
WO2021077070A1 (en) 2019-10-18 2021-04-22 Yale University Compositions and methods for inhibition of cell-penetrating antibodies
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
US11850220B2 (en) 2020-05-19 2023-12-26 Augusta University Research Institute, Inc. Synthesis of ibuprofen hybrid conjugates as anti-inflammatory and analgesic agents
US11858908B2 (en) 2021-01-19 2024-01-02 Augusta University Research Institute, Inc. Compositions and methods for inhibiting IDO1

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296230A (en) * 1985-02-25 1994-03-22 Rutgers, The State University Of New Jersey Transdermal fertility control system and process
CH674618A5 (da) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US5223261A (en) * 1988-02-26 1993-06-29 Riker Laboratories, Inc. Transdermal estradiol delivery system
DE3910578A1 (de) * 1989-03-29 1990-10-04 Schering Ag Mittel zur transdermalen applikation enthaltend gestoden
US5057734A (en) * 1988-11-30 1991-10-15 Toyota Jidosha Kabushiki Kaisha Apparatus for driving piezoelectric element for closing and opening valve member
IL92496A0 (en) * 1988-12-01 1990-08-31 Schering Corp Compositions for transdermal delivery of estradiol
US5053227A (en) * 1989-03-22 1991-10-01 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
ATE107517T1 (de) * 1989-05-25 1994-07-15 Takeda Chemical Industries Ltd Transdermales therapeutisches mittel.
JP2718433B2 (ja) * 1989-09-08 1998-02-25 シグナス インコーポレイテッド 経皮ドラッグデリバリーのための固体マトリックスシステム
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
DE3942232A1 (de) * 1989-12-21 1991-06-27 Beiersdorf Ag Schmelzhaftkleber auf acrylatbasis
DE4020144A1 (de) * 1990-06-25 1992-01-09 Lohmann Therapie Syst Lts Pflaster mit hohem gehalt an weichmachenden inhaltsstoffen
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
US5518734A (en) * 1991-09-25 1996-05-21 Beta Pharmaceuticals Co. Transdermal delivery system for estradiol and process for manufacturing said device
DE4210711A1 (de) * 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
US5676968A (en) * 1991-10-31 1997-10-14 Schering Aktiengesellschaft Transdermal therapeutic systems with crystallization inhibitors
IT1253265B (it) * 1991-11-25 1995-07-14 Rotta Research Lab Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo.
US5314685A (en) * 1992-05-11 1994-05-24 Agouron Pharmaceuticals, Inc. Anhydrous formulations for administering lipophilic agents
GB2273044B (en) * 1992-12-02 1997-04-09 Pacific Chem Co Ltd Medicinal patches for percutaneous administration
DE4240806A1 (de) * 1992-12-01 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 14alpha,17alpha-Ethanoestra-1,3,5(10)-trien-3,17beta-diol
AU5718494A (en) * 1992-12-31 1994-08-15 Sunkyong Industries Co., Ltd. Enhanced pharmaceutical compositions for skin penetration
DE4309830C1 (de) * 1993-03-26 1994-05-05 Lohmann Therapie Syst Lts Wirkstoffpflaster für die Abgabe von Estradiol an die Haut
US5385736A (en) * 1993-07-12 1995-01-31 Minnesota Mining And Manufacturing Company Transdermal melatonin delivery system
WO1995005137A1 (en) * 1993-08-16 1995-02-23 Cygnus Therapeutic Systems Transdermal delivery system using a combination of permeation enhancers
DE4333595A1 (de) * 1993-10-01 1995-04-06 Labtec Gmbh Transdermales therapeutisches System zur Applikation von Arzneimitteln auf die Haut
JPH09510697A (ja) * 1994-01-27 1997-10-28 シエーリング アクチエンゲゼルシヤフト 14α,17α−エタノエストラ−1,3,5(10)−トリエン−3,17β−ジオールを含有する経皮投与のための薬剤
DK0781122T3 (da) * 1994-09-14 2000-10-30 Minnesota Mining & Mfg Matrix til transdermal lægmiddelafgivelse
WO1996008255A1 (en) * 1994-09-14 1996-03-21 Minnesota Mining And Manufacturing Company Transdermal device for delivery of levonorgestrel

Also Published As

Publication number Publication date
ATE212234T1 (de) 2002-02-15
NO980277L (no) 1998-01-21
AU6786696A (en) 1997-02-18
EP0840621B1 (de) 2002-01-23
PL324552A1 (en) 1998-06-08
KR19990035795A (ko) 1999-05-25
CA2227538A1 (en) 1997-02-06
NO980277D0 (no) 1998-01-21
SK8198A3 (en) 1998-06-03
DE19526864A1 (de) 1997-01-23
DE19680582D2 (de) 1998-10-29
NZ316026A (en) 1999-08-30
HUP9900301A2 (hu) 1999-06-28
DE59608650D1 (de) 2002-03-14
ES2171710T3 (es) 2002-09-16
CN1195994A (zh) 1998-10-14
HUP9900301A3 (en) 1999-11-29
CZ20498A3 (cs) 1998-06-17
PT840621E (pt) 2002-06-28
EP0840621A1 (de) 1998-05-13
MX9800469A (es) 1998-09-30
US5985311A (en) 1999-11-16
JPH11504038A (ja) 1999-04-06
WO1997003698A1 (de) 1997-02-06
BR9609794A (pt) 1999-03-16

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