DK0832211T3 - Oligonucleotider, der er specifikke for hepatitis B-virus. - Google Patents
Oligonucleotider, der er specifikke for hepatitis B-virus.Info
- Publication number
- DK0832211T3 DK0832211T3 DK96918671T DK96918671T DK0832211T3 DK 0832211 T3 DK0832211 T3 DK 0832211T3 DK 96918671 T DK96918671 T DK 96918671T DK 96918671 T DK96918671 T DK 96918671T DK 0832211 T3 DK0832211 T3 DK 0832211T3
- Authority
- DK
- Denmark
- Prior art keywords
- hepatitis
- virus
- oligonucleotides specific
- hbv
- kits
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/313—Phosphorodithioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/314—Phosphoramidates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46739795A | 1995-06-06 | 1995-06-06 | |
| PCT/EP1996/002432 WO1996039502A1 (en) | 1995-06-06 | 1996-06-04 | Oligonucleotides specific for hepatitis b virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0832211T3 true DK0832211T3 (da) | 2003-05-26 |
Family
ID=23855522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96918671T DK0832211T3 (da) | 1995-06-06 | 1996-06-04 | Oligonucleotider, der er specifikke for hepatitis B-virus. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5856459A (da) |
| EP (1) | EP0832211B1 (da) |
| AT (1) | ATE233318T1 (da) |
| AU (1) | AU6125296A (da) |
| CA (1) | CA2226458A1 (da) |
| DE (1) | DE69626393T2 (da) |
| DK (1) | DK0832211T3 (da) |
| ES (1) | ES2188760T3 (da) |
| WO (1) | WO1996039502A1 (da) |
| ZA (1) | ZA964445B (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040054156A1 (en) * | 1992-05-14 | 2004-03-18 | Kenneth Draper | Method and reagent for inhibiting hepatitis B viral replication |
| US5646262A (en) | 1994-07-28 | 1997-07-08 | Georgetown University | Antisense oligonucleotides against hepatitis B viral replication |
| US5985662A (en) * | 1995-07-13 | 1999-11-16 | Isis Pharmaceuticals Inc. | Antisense inhibition of hepatitis B virus replication |
| JP4091663B2 (ja) | 1996-10-31 | 2008-05-28 | バイオジェン アイデック マサチューセッツ インコーポレイテッド | Ｂ型肝炎インヒビター |
| CN1057302C (zh) * | 1997-08-27 | 2000-10-11 | 中国科学院上海生物化学研究所 | 抑制乙型肝炎病毒复制的反义脱氧寡核苷酸 |
| CN1215058A (zh) * | 1997-10-21 | 1999-04-28 | 中国科学院上海生物化学研究所 | 新的三链形成寡核苷酸结构及其在抗乙肝病毒中的应用 |
| WO2000032625A1 (en) | 1998-12-04 | 2000-06-08 | Biogen, Inc. | Hbv core antigen particles with multiple immunogenic components attached via peptide ligands |
| AU2001254670A1 (en) * | 2000-03-02 | 2001-09-12 | Akzo Nobel N.V. | Detection of hepatitis b virus rna |
| US6583279B1 (en) | 2001-01-26 | 2003-06-24 | Becton, Dickinson And Company | Sequences and methods for detection of hepatitis B virus |
| CA2442092A1 (en) * | 2001-03-26 | 2002-10-17 | Ribozyme Pharmaceuticals, Inc. | Oligonucleotide mediated inhibition of hepatitis b virus and hepatitis c virus replication |
| WO2002092006A2 (en) | 2001-05-16 | 2002-11-21 | Micrologix Biotech, Inc. | Nucleic acid-based compounds and methods of use thereof |
| US20030140362A1 (en) * | 2001-06-08 | 2003-07-24 | Dennis Macejak | In vivo models for screening inhibitors of hepatitis B virus |
| EP1513958B1 (en) * | 2002-06-14 | 2011-08-10 | Gen-Probe Incorporated | Compositions for detecting hepatitis b virus |
| EP1403385A1 (en) * | 2002-09-27 | 2004-03-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for assaying replication of HBV and testing susceptibility to drugs |
| PT2241325E (pt) * | 2002-10-29 | 2012-04-12 | Coley Pharm Gmbh | Utilização de oligonucleótidos cpg no tratamento de infecção com vírus da hepatite c |
| EA201290152A1 (ru) | 2009-10-16 | 2012-12-28 | Глаксо Груп Лимитед | Антисмысловые ингибиторы вируса гепатита в (hbv) |
| RU2667524C2 (ru) * | 2011-04-21 | 2018-09-21 | Ионис Фармасьютикалз, Инк. | Модулирование экспрессии вируса гепатита b (hbv) |
| CN113430196A (zh) | 2011-06-30 | 2021-09-24 | 箭头药业股份有限公司 | 用于抑制乙型肝炎病毒的基因表达的组合物和方法 |
| GB201408623D0 (en) | 2014-05-15 | 2014-07-02 | Santaris Pharma As | Oligomers and oligomer conjugates |
| CA2991639A1 (en) | 2015-08-07 | 2017-02-16 | Arrowhead Pharmaceuticals, Inc. | Rnai therapy for hepatitis b virus infection |
| JOP20170161A1 (ar) | 2016-08-04 | 2019-01-30 | Arrowhead Pharmaceuticals Inc | عوامل RNAi للعدوى بفيروس التهاب الكبد ب |
| KR102273071B1 (ko) * | 2018-06-12 | 2021-07-05 | 주식회사 에이엠사이언스 | B형 간염 예방 또는 치료용 조성물 |
| WO2019240504A1 (en) * | 2018-06-12 | 2019-12-19 | Am Sciences Co., Ltd. | Modified oligonucleotides for inhibition of target gene expression |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225326A (en) * | 1988-08-31 | 1993-07-06 | Research Development Foundation | One step in situ hybridization assay |
| US5610050A (en) * | 1990-04-20 | 1997-03-11 | The General Hospital Corporation | Methods of preventing viral replication |
| AU662304B2 (en) * | 1990-10-22 | 1995-08-31 | Fox Chase Cancer Center | DNA construct for providing RNA therapy |
| KR100252547B1 (ko) * | 1991-09-05 | 2000-09-01 | 프레드 마리얀스키 | 폴리-또는 올리고누클레오티드의 세포로의 표적화된 전달 |
| US5585479A (en) * | 1992-07-24 | 1996-12-17 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ELAM-I RNA |
| WO1995017414A1 (en) * | 1993-12-23 | 1995-06-29 | Apollon, Inc. | Anti-hepatitis b viral oligonucleotides |
| US5728518A (en) * | 1994-01-12 | 1998-03-17 | The Immune Response Corporation | Antiviral poly-and oligonucleotides |
| US5646262A (en) * | 1994-07-28 | 1997-07-08 | Georgetown University | Antisense oligonucleotides against hepatitis B viral replication |
-
1995
- 1995-06-06 US US08/468,352 patent/US5856459A/en not_active Expired - Lifetime
-
1996
- 1996-05-30 ZA ZA964445A patent/ZA964445B/xx unknown
- 1996-06-04 EP EP96918671A patent/EP0832211B1/en not_active Expired - Lifetime
- 1996-06-04 CA CA002226458A patent/CA2226458A1/en not_active Abandoned
- 1996-06-04 DK DK96918671T patent/DK0832211T3/da active
- 1996-06-04 AU AU61252/96A patent/AU6125296A/en not_active Abandoned
- 1996-06-04 ES ES96918671T patent/ES2188760T3/es not_active Expired - Lifetime
- 1996-06-04 WO PCT/EP1996/002432 patent/WO1996039502A1/en active IP Right Grant
- 1996-06-04 AT AT96918671T patent/ATE233318T1/de not_active IP Right Cessation
- 1996-06-04 DE DE69626393T patent/DE69626393T2/de not_active Expired - Lifetime
-
1997
- 1997-07-28 US US08/901,612 patent/US6984729B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69626393D1 (de) | 2003-04-03 |
| AU6125296A (en) | 1996-12-24 |
| ATE233318T1 (de) | 2003-03-15 |
| ZA964445B (en) | 1996-12-06 |
| US5856459A (en) | 1999-01-05 |
| DE69626393T2 (de) | 2003-12-04 |
| WO1996039502A1 (en) | 1996-12-12 |
| EP0832211B1 (en) | 2003-02-26 |
| ES2188760T3 (es) | 2003-07-01 |
| CA2226458A1 (en) | 1996-12-12 |
| EP0832211A1 (en) | 1998-04-01 |
| US6984729B1 (en) | 2006-01-10 |
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