DK0832101T3 - Urethan-formidlede, GST-specifikke molekylfrigörelsessystemer - Google Patents

Urethan-formidlede, GST-specifikke molekylfrigörelsessystemer

Info

Publication number
DK0832101T3
DK0832101T3 DK96918420T DK96918420T DK0832101T3 DK 0832101 T3 DK0832101 T3 DK 0832101T3 DK 96918420 T DK96918420 T DK 96918420T DK 96918420 T DK96918420 T DK 96918420T DK 0832101 T3 DK0832101 T3 DK 0832101T3
Authority
DK
Denmark
Prior art keywords
glu
gly
asp
formula
gst
Prior art date
Application number
DK96918420T
Other languages
Danish (da)
English (en)
Inventor
Lawrence M Kauvar
Matthew H Lyttle
Apparao Satyam
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DK0832101T3 publication Critical patent/DK0832101T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK96918420T 1995-06-07 1996-06-07 Urethan-formidlede, GST-specifikke molekylfrigörelsessystemer DK0832101T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/476,119 US5908919A (en) 1993-10-01 1995-06-07 Urethane mediated, GST specific molecular release systems
PCT/US1996/009831 WO1996040739A2 (en) 1995-06-07 1996-06-07 Urethane mediated, gst specific molecular release systems

Publications (1)

Publication Number Publication Date
DK0832101T3 true DK0832101T3 (da) 2004-11-29

Family

ID=23890586

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96918420T DK0832101T3 (da) 1995-06-07 1996-06-07 Urethan-formidlede, GST-specifikke molekylfrigörelsessystemer

Country Status (10)

Country Link
US (1) US5908919A (de)
EP (1) EP0832101B1 (de)
JP (1) JPH11507370A (de)
AT (1) ATE273318T1 (de)
AU (1) AU722595B2 (de)
CA (1) CA2224191A1 (de)
DE (1) DE69633126T2 (de)
DK (1) DK0832101T3 (de)
ES (1) ES2227592T3 (de)
WO (1) WO1996040739A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5880097A (en) * 1996-01-04 1999-03-09 Terrapin Techologies, Inc. Tethered prodrugs
IL137164A0 (en) 1998-01-23 2001-07-24 Newbiotics Inc Enzyme catalyzed therapeutic agents
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
BR0012676A (pt) 1999-07-22 2003-07-01 Newbiotics Inc Métodos para tratamento de tumores resistentes a terapia
US7172905B2 (en) * 2001-08-07 2007-02-06 The University Of Chicago Polypeptide immobilization
EP2500729A1 (de) * 2002-07-05 2012-09-19 The University of Chicago Charakterisierung von Biochips mit selbstorganisierten Monoschichten
DE602006003064D1 (en) * 2005-01-06 2008-11-20 Telik Inc Tripeptid- und tetrapeptid-thioether
ES2584381T3 (es) * 2010-05-05 2016-09-27 Prolynx Llc Liberación controlada de compuestos activos desde conjugados macromoleculares

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
CA1255586A (en) * 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
WO1986006487A1 (en) * 1985-04-22 1986-11-06 Commonwealth Serum Laboratories Commission Method for determining mimotopes
WO1987004440A1 (en) * 1986-01-23 1987-07-30 Pfizer Inc. Heptanoyl-glu-asp-ala-amino acid immunostimulants
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US4963263A (en) * 1988-03-24 1990-10-16 Terrapin Technologies, Inc. Method of identity analyte-binding peptides
AU5435990A (en) * 1989-04-13 1990-11-05 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Monoclonal antibodies to human glutathione s transferase pi
JP2919867B2 (ja) * 1989-09-27 1999-07-19 千寿製薬株式会社 抗腫瘍剤
ATE129019T1 (de) * 1990-05-07 1995-10-15 Dade Int Inc Verfahren und vorrichtung zur ausführung des zytotoxizitätsassays auf tumorzellen.
US5204241A (en) * 1990-10-22 1993-04-20 Oxi-Gene Inc. Glutathione-S-transferase mu as a measure of drug resistance
US5545621A (en) * 1991-04-29 1996-08-13 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
DE69227594D1 (de) * 1991-04-29 1998-12-17 Terrapin Tech Inc Verfahren zur erkennung und behandlung anomaler zellen
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
AU4406793A (en) * 1992-06-04 1993-12-30 Clover Consolidated, Limited Water-soluble polymeric carriers for drug delivery

Also Published As

Publication number Publication date
DE69633126T2 (de) 2005-08-11
JPH11507370A (ja) 1999-06-29
AU6108896A (en) 1996-12-30
AU722595B2 (en) 2000-08-10
EP0832101B1 (de) 2004-08-11
US5908919A (en) 1999-06-01
CA2224191A1 (en) 1996-12-19
WO1996040739A2 (en) 1996-12-19
WO1996040739A3 (en) 1997-01-30
ES2227592T3 (es) 2005-04-01
ATE273318T1 (de) 2004-08-15
EP0832101A2 (de) 1998-04-01
DE69633126D1 (de) 2004-09-16

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