DK0816356T3 - 1-(2-(1-Piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazolderivater og deres farmaceutiske anvendelse - Google Patents
1-(2-(1-Piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazolderivater og deres farmaceutiske anvendelseInfo
- Publication number
- DK0816356T3 DK0816356T3 DK97304485T DK97304485T DK0816356T3 DK 0816356 T3 DK0816356 T3 DK 0816356T3 DK 97304485 T DK97304485 T DK 97304485T DK 97304485 T DK97304485 T DK 97304485T DK 0816356 T3 DK0816356 T3 DK 0816356T3
- Authority
- DK
- Denmark
- Prior art keywords
- piperidinyl
- dihydro
- ethyl
- pharmaceutical use
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9613423.4A GB9613423D0 (en) | 1996-06-26 | 1996-06-26 | Pharmaceutical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0816356T3 true DK0816356T3 (da) | 2001-01-02 |
Family
ID=10795937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97304485T DK0816356T3 (da) | 1996-06-26 | 1997-06-25 | 1-(2-(1-Piperidinyl)-1-ethyl)-1,3-dihydro-2H-benzimidazolderivater og deres farmaceutiske anvendelse |
Country Status (11)
Country | Link |
---|---|
US (1) | US6075039A (da) |
EP (1) | EP0816356B1 (da) |
JP (1) | JPH1059962A (da) |
AT (1) | ATE197299T1 (da) |
CA (1) | CA2208652A1 (da) |
DE (1) | DE69703413T2 (da) |
DK (1) | DK0816356T3 (da) |
ES (1) | ES2151706T3 (da) |
GB (1) | GB9613423D0 (da) |
GR (1) | GR3035251T3 (da) |
PT (1) | PT816356E (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6521623B1 (en) | 2000-09-19 | 2003-02-18 | Boehringer Ingelheim Pharma Kg | N,N'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors |
WO2002024661A2 (en) * | 2000-09-19 | 2002-03-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New n, n'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors |
JPWO2002060878A1 (ja) * | 2001-01-30 | 2004-06-03 | 住友製薬株式会社 | ベンズイミダゾリジノン誘導体 |
US7183410B2 (en) | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
CA2626134C (en) | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
JP2009541443A (ja) | 2006-06-30 | 2009-11-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 尿失禁及び関連疾患の治療のためのフリバンセリン |
JP5793828B2 (ja) | 2006-08-14 | 2015-10-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | フリバンセリンの製剤及びその製造方法 |
CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
EP2056797A2 (en) | 2006-08-25 | 2009-05-13 | Boehringer Ingelheim International GmbH | Controlled release system and method for manufacturing the same |
CL2008002693A1 (es) | 2007-09-12 | 2009-10-16 | Boehringer Ingelheim Int | Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad |
KR102316234B1 (ko) | 2018-07-26 | 2021-10-22 | 주식회사 종근당 | 히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물 |
CA3139026A1 (en) * | 2019-05-31 | 2020-12-03 | Chang Sik Lee | 1,3,4-oxadiazole derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE659364A (da) * | 1964-02-05 | |||
US4035369A (en) * | 1975-10-08 | 1977-07-12 | Janssen Pharmaceutica N.V. | 1-Benzazolylalkyl-4-substituted-piperidines |
US4254127A (en) * | 1980-04-03 | 1981-03-03 | Janssen Pharmaceutica, N.V. | 1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives |
EP0181793B1 (fr) * | 1984-10-16 | 1988-07-27 | Synthelabo | Dérivés de pipéridine, leur préparation et leur application en thérapeutique |
JPH0615529B2 (ja) * | 1985-04-01 | 1994-03-02 | エーザイ株式会社 | 新規ピペリジン誘導体 |
EP0429341A3 (en) * | 1989-11-20 | 1991-11-13 | Rhone-Poulenc Sante | Heterocyclic derivatives, their preparation and pharmaceuticals containing them |
JPH09505029A (ja) * | 1993-07-19 | 1997-05-20 | 藤沢薬品工業株式会社 | ドパミン受容体作動薬、5−HT受容体拮抗薬あるいはα▲下1▼受容体拮抗薬として有用なベンズイミダゾール誘導体 |
FR2722190B1 (fr) * | 1994-07-05 | 1996-10-04 | Sanofi Sa | Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant |
FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
FR2725986B1 (fr) * | 1994-10-21 | 1996-11-29 | Adir | Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
1996
- 1996-06-26 GB GBGB9613423.4A patent/GB9613423D0/en active Pending
-
1997
- 1997-06-23 CA CA002208652A patent/CA2208652A1/en not_active Abandoned
- 1997-06-24 US US08/880,450 patent/US6075039A/en not_active Expired - Fee Related
- 1997-06-25 DK DK97304485T patent/DK0816356T3/da active
- 1997-06-25 EP EP97304485A patent/EP0816356B1/en not_active Expired - Lifetime
- 1997-06-25 PT PT97304485T patent/PT816356E/pt unknown
- 1997-06-25 ES ES97304485T patent/ES2151706T3/es not_active Expired - Lifetime
- 1997-06-25 DE DE69703413T patent/DE69703413T2/de not_active Expired - Fee Related
- 1997-06-25 AT AT97304485T patent/ATE197299T1/de not_active IP Right Cessation
- 1997-06-25 JP JP9168670A patent/JPH1059962A/ja active Pending
-
2001
- 2001-01-17 GR GR20010400071T patent/GR3035251T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB9613423D0 (en) | 1996-08-28 |
GR3035251T3 (en) | 2001-04-30 |
ATE197299T1 (de) | 2000-11-15 |
CA2208652A1 (en) | 1997-12-26 |
DE69703413T2 (de) | 2001-03-15 |
EP0816356A1 (en) | 1998-01-07 |
US6075039A (en) | 2000-06-13 |
ES2151706T3 (es) | 2001-01-01 |
PT816356E (pt) | 2001-04-30 |
JPH1059962A (ja) | 1998-03-03 |
DE69703413D1 (de) | 2000-12-07 |
EP0816356B1 (en) | 2000-11-02 |
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