DK0813420T3 - Behandling af hjerneischæmi og hjerneskader med et neurobeskyttende middel - Google Patents

Behandling af hjerneischæmi og hjerneskader med et neurobeskyttende middel

Info

Publication number
DK0813420T3
DK0813420T3 DK96901587T DK96901587T DK0813420T3 DK 0813420 T3 DK0813420 T3 DK 0813420T3 DK 96901587 T DK96901587 T DK 96901587T DK 96901587 T DK96901587 T DK 96901587T DK 0813420 T3 DK0813420 T3 DK 0813420T3
Authority
DK
Denmark
Prior art keywords
brain
treatment
neuroprotective agent
ischemia
damage
Prior art date
Application number
DK96901587T
Other languages
Danish (da)
English (en)
Inventor
Eskil Elmer
Hiroyuki Uchino
Marcus Keep
Merab Kokaia
Zaal Kokaia
Hakan Widner
Qi Zhao
Keiko Uchino
Original Assignee
Maas Biolab Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maas Biolab Llc filed Critical Maas Biolab Llc
Application granted granted Critical
Publication of DK0813420T3 publication Critical patent/DK0813420T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96901587T 1995-01-20 1996-01-18 Behandling af hjerneischæmi og hjerneskader med et neurobeskyttende middel DK0813420T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9500209A SE520730C2 (sv) 1995-01-20 1995-01-20 Behandling av hjärnischemi och hjärnskador med ett neuroprotektivt läkemedel
PCT/SE1996/000036 WO1996022104A1 (en) 1995-01-20 1996-01-18 Treatment of cerebral ischemia and cerebral damage with neuroprotective agent

Publications (1)

Publication Number Publication Date
DK0813420T3 true DK0813420T3 (da) 2002-09-30

Family

ID=20396911

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96901587T DK0813420T3 (da) 1995-01-20 1996-01-18 Behandling af hjerneischæmi og hjerneskader med et neurobeskyttende middel

Country Status (18)

Country Link
US (1) US5972924A (ja)
EP (1) EP0813420B1 (ja)
JP (1) JP3643380B2 (ja)
CN (1) CN1123359C (ja)
AP (1) AP734A (ja)
AT (1) ATE218360T1 (ja)
AU (1) AU712974B2 (ja)
CA (1) CA2210241C (ja)
CZ (1) CZ291233B6 (ja)
DE (1) DE69621603T2 (ja)
DK (1) DK0813420T3 (ja)
ES (1) ES2176432T3 (ja)
MX (1) MX9706362A (ja)
NZ (1) NZ300699A (ja)
PT (1) PT813420E (ja)
RU (1) RU2194527C2 (ja)
SE (1) SE520730C2 (ja)
WO (1) WO1996022104A1 (ja)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19711795C2 (de) * 1997-03-21 2001-03-08 Apogepha Arzneimittel Gmbh Verwendung von Cyclosporin für die Behandlung von Myokardinfarkten und deren Folgen
US20040202645A1 (en) * 2003-04-08 2004-10-14 Khan Nisar Ahmed Administration of gene-regulatory peptides
US8680059B2 (en) * 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
US20050227925A1 (en) * 2004-04-08 2005-10-13 Robbert Benner Compositions capable of reducing elevated blood urea concentration
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
EP1138692A1 (en) 2000-03-29 2001-10-04 Erasmus Universiteit Rotterdam Fragments of human chorionic gonadotropin (hcg) as immunoregulator
US6844315B2 (en) 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
US6921751B1 (en) * 1998-05-20 2005-07-26 Erasmus Universiteit Rotterdam Immunoregulator
AP1040A (en) * 1998-09-17 2002-01-30 Panacea Biotec Ltd A novel composition containing cyclosporin.
CN1322136A (zh) * 1998-09-23 2001-11-14 马库斯·基普 用于选择性神经元辐射防护的神经亲免素类物质
DE19857609A1 (de) 1998-12-14 2000-06-15 Hannelore Ehrenreich Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
JP2002541162A (ja) * 1999-04-13 2002-12-03 ノース・ショア−ロング・アイランド・ジューイッシュ・リサーチ・インスティテュート 発作による脳障害防止法
EP1214293A1 (en) 1999-09-08 2002-06-19 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
DE19961733A1 (de) * 1999-12-21 2001-06-28 Ciclomulsion Ag Cyclosporin(e) enthaltende hypertone pharmazeutische Zubereitung zur Anwendung bei neurologischen Erkrankungen und als Neuroprotektivum sowie Verfahren zu ihrer Herstellung
KR20010069066A (ko) * 2000-01-12 2001-07-23 이종원 저산소 농도하에서 생존이 가능하도록 하는 동물세포의배양방법
US7358330B2 (en) 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
EP1274377A2 (en) 2000-04-07 2003-01-15 The General Hospital Corporation doing business as Massachusetts General Hospital Methods and apparatus for thermally affecting tissue
US6652566B2 (en) 2000-10-05 2003-11-25 Seacoast Technologies, Inc. Neurosurgical device for thermal therapy including spiral element
US6656971B2 (en) 2001-01-25 2003-12-02 Guilford Pharmaceuticals Inc. Trisubstituted carbocyclic cyclophilin binding compounds and their use
US6936589B2 (en) * 2001-09-28 2005-08-30 Albert T. Naito Parenteral delivery systems
KR100982466B1 (ko) 2001-10-19 2010-09-16 이소테크니카 인코포레이티드 시클로스포린 유사체의 합성
US20040013661A1 (en) * 2001-12-21 2004-01-22 Gert Wensvoort Stratification
US20030220261A1 (en) * 2001-12-21 2003-11-27 Khan Nisar Ahmed Treatment of iatrogenic disease
US20030224995A1 (en) * 2001-12-21 2003-12-04 Khan Nisar Ahmed Treatment of burns
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US20030220260A1 (en) * 2001-12-21 2003-11-27 Khan Nisar Ahmed Peptide compositions
US20080242837A1 (en) * 2001-12-21 2008-10-02 Khan Nisar A Peptide compositions
US20030220257A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of trauma
US7560433B2 (en) 2001-12-21 2009-07-14 Biotempt B.V. Treatment of multiple sclerosis (MS)
US7501391B2 (en) * 2001-12-21 2009-03-10 Biotempt B.V. Treatment of transplant survival
US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
US7074775B2 (en) * 2004-09-14 2006-07-11 Miller Landon C G Aminobutyramide conjugate and a pharmaceutical composition for treatment of neuronal disorders
US8420602B2 (en) * 2004-09-14 2013-04-16 Landon C. G. Miller Endocannabinoid conjugate and a pharmaceutical composition for treatment of neuronal disorders
SG163567A1 (en) * 2005-07-05 2010-08-30 Biotempt Bv Treatment of tumors
EP1864692A1 (en) * 2006-06-07 2007-12-12 Biotempt B.V. Use of peptides for the control of radiation injury
CN103479603B (zh) * 2006-08-23 2016-06-22 蒙大拿大学 减轻神经元细胞损害的方法
PL2120991T3 (pl) * 2007-02-12 2014-07-31 Biotempt Bv Leczenie urazów krwotocznych krótkimi oligopeptydami
JP2013522311A (ja) * 2010-03-15 2013-06-13 ステルス ペプチドズ インターナショナル インコーポレイテッド シクロスポリンおよび芳香族カチオン性ペプチドを用いた併用療法
RU2475233C2 (ru) * 2010-12-01 2013-02-20 Учреждение Российской академии наук Институт кристаллографии им. А.В. Шубникова РАН Фармакологическая композиция, предназначенная для интраназального введения с целью доставки в мозг фармакологически активного компонента, и способ ее получения
PT2651965T (pt) 2010-12-15 2019-01-28 Contravir Pharmaceuticals Inc Moléculas analógas de ciclosporinas modificadas ao nivel dos aminoácidos 1 e 3
CN102784102A (zh) * 2012-08-28 2012-11-21 赵继红 一种河豚毒素口服液态制剂及其制备方法
US10123969B2 (en) 2015-10-15 2018-11-13 Wisconsin Alumni Research Foundation Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid
US11745029B2 (en) 2018-05-30 2023-09-05 Zap Surgical Systems, Inc. Radiosurgical neuromodulation close to critical structures
WO2021048871A1 (en) 2019-09-15 2021-03-18 Celagenex Research (India) Pvt. Ltd. Synergistic bioactive compositions for treating neurological disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds

Also Published As

Publication number Publication date
AU712974B2 (en) 1999-11-18
CZ233697A3 (cs) 1998-07-15
SE520730C2 (sv) 2003-08-19
CA2210241C (en) 2000-06-20
DE69621603T2 (de) 2002-09-19
EP0813420B1 (en) 2002-06-05
NZ300699A (en) 1998-05-27
EP0813420A1 (en) 1997-12-29
ATE218360T1 (de) 2002-06-15
DE69621603D1 (de) 2002-07-11
WO1996022104A1 (en) 1996-07-25
US5972924A (en) 1999-10-26
SE9500209D0 (sv) 1995-01-20
CZ291233B6 (cs) 2003-01-15
AP734A (en) 1999-02-15
JPH11504617A (ja) 1999-04-27
ES2176432T3 (es) 2002-12-01
CN1178469A (zh) 1998-04-08
MX9706362A (es) 1998-07-31
PT813420E (pt) 2002-10-31
CA2210241A1 (en) 1996-07-25
CN1123359C (zh) 2003-10-08
JP3643380B2 (ja) 2005-04-27
SE9500209L (sv) 1996-07-21
AP9701049A0 (en) 1997-10-31
RU2194527C2 (ru) 2002-12-20
AU4592496A (en) 1996-08-07

Similar Documents

Publication Publication Date Title
DK0813420T3 (da) Behandling af hjerneischæmi og hjerneskader med et neurobeskyttende middel
DK0629347T3 (da) Antibakterielt middel og behandling af genstande dermed
DK1994937T3 (da) Forebyggelse og behandling af amyloidogen sygdom
IS4564A (is) Framleiðsla og kristalform af 2-methýl-thíeno-bensodíasepín
DE69532671D1 (de) Endoprothesen und stents
BR9406209A (pt) Derivados heterociclicos no tratamento de isquemia e doenças relacionadas
DE69627188T2 (de) Brille und brillenfassung
IS4481A (is) Díhýdrópyramídín og notkun þeirra
DE69434376D1 (de) Videotrainingsverfahren und display
NO940622D0 (no) Rensing fremgangsmåte og apparat
NO920780D0 (no) Fremgangsmaate og anordning for behandling av epilepsi
KR940024241U (ko) 합체식 마스크와 보호안경 구조물
DE69333528D1 (de) D-n-carbamoylaminosaureamidohydrolase und hydantoinase
DE69405421T2 (de) Verstellbares Kettenrad und Komponenten davon
NO932224D0 (no) Pleiemiddel for haarde og myke kontaktlinser
DK0998291T3 (da) Behandling af diabetes med thiazolidindion og sulphonylurinstof
DE4394199T1 (de) Handgelenk-Stütz- und Zieh-Vorrichtung
DE69426135T2 (de) Fixiervorrichtung und Fixierwalze
NO952652D0 (no) Termisk behandling av karbonholdig materiale
SI0813420T1 (en) Treatment of cerebral ischemia and cerebral damage with neuroprotective agent
NO981939D0 (no) Tiomorfinaner med neurobeskyttende aktivitet
KR940018945U (ko) 치질치료 및 예방용 좌욕조
NO922988L (no) Potensfremmende middel og fremstilling derav
ATA198394A (de) Oberschenkelstütze und -schutz
DE69217922D1 (de) Handgelenkorthese