DK0811063T3 - Kemokin-receptor 88C og dens antistoffer - Google Patents

Kemokin-receptor 88C og dens antistoffer

Info

Publication number
DK0811063T3
DK0811063T3 DK96945669T DK96945669T DK0811063T3 DK 0811063 T3 DK0811063 T3 DK 0811063T3 DK 96945669 T DK96945669 T DK 96945669T DK 96945669 T DK96945669 T DK 96945669T DK 0811063 T3 DK0811063 T3 DK 0811063T3
Authority
DK
Denmark
Prior art keywords
chemokine receptors
antibodies
modulators
ligands
chemokine receptor
Prior art date
Application number
DK96945669T
Other languages
Danish (da)
English (en)
Inventor
Patrick W Gray
Vicki L Schweickart
Carol J Raport
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24302427&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0811063(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of DK0811063T3 publication Critical patent/DK0811063T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96945669T 1995-12-20 1996-12-20 Kemokin-receptor 88C og dens antistoffer DK0811063T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/575,967 US6265184B1 (en) 1995-12-20 1995-12-20 Polynucleotides encoding chemokine receptor 88C
US08/661,393 US6268477B1 (en) 1995-12-20 1996-06-07 Chemokine receptor 88-C

Publications (1)

Publication Number Publication Date
DK0811063T3 true DK0811063T3 (da) 2006-04-10

Family

ID=24302427

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07013395.4T DK1870465T3 (da) 1995-12-20 1996-12-20 Fremgangsmåde til chemokinreceptor 88C
DK96945669T DK0811063T3 (da) 1995-12-20 1996-12-20 Kemokin-receptor 88C og dens antistoffer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK07013395.4T DK1870465T3 (da) 1995-12-20 1996-12-20 Fremgangsmåde til chemokinreceptor 88C

Country Status (17)

Country Link
US (7) US6265184B1 (de)
EP (3) EP1642975A3 (de)
JP (4) JP3288384B2 (de)
CN (2) CN1827646A (de)
AT (2) ATE458052T1 (de)
AU (1) AU730463B2 (de)
BR (1) BR9607300A (de)
CA (1) CA2213331C (de)
CZ (1) CZ261097A3 (de)
DE (2) DE69635406T3 (de)
DK (2) DK1870465T3 (de)
ES (2) ES2255716T5 (de)
HU (1) HUP9801127A3 (de)
NO (2) NO973800L (de)
PL (2) PL192071B1 (de)
SK (1) SK112897A3 (de)
WO (1) WO1997022698A2 (de)

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US20040151719A1 (en) * 1995-06-06 2004-08-05 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
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US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US7018627B1 (en) 1995-06-07 2006-03-28 Icos Corporation Macrophage derived chemokine (MDC), MDC analogs, MDC inhibitor substances, and uses thereof
CA2224003C (en) * 1995-06-07 2010-04-13 Progenics Pharmaceuticals, Inc. Fluorescence resonance energy transfer screening assay for the identification of hiv-1 envelope glycoprotein-medicated cell
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US7118859B2 (en) * 1996-01-17 2006-10-10 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
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DE69731373T2 (de) 1996-03-01 2006-03-09 Euroscreen S.A. Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
US7858298B1 (en) * 1996-04-01 2010-12-28 Progenics Pharmaceuticals Inc. Methods of inhibiting human immunodeficiency virus type 1 (HIV-1) infection through the administration of CCR5 chemokine receptor antagonists
US6344545B1 (en) * 1996-06-14 2002-02-05 Progenics Pharmaceuticals, Inc. Method for preventing HIV-1 infection of CD4+ cells
AU728512B2 (en) 1996-04-02 2001-01-11 Progenics Pharmaceuticals, Inc. Method for preventing HIV-1 infection of CD4+ cells
WO1997041225A2 (en) * 1996-04-26 1997-11-06 Incyte Pharmaceuticals, Inc. Mammalian mixed lymphocyte receptors, chemokine receptors [mmlr-ccr]
EP1012190A4 (de) * 1996-04-26 2004-04-28 Merck & Co Inc Eotaxinrezeptor aus Eosinophilen
US6271347B1 (en) * 1996-04-26 2001-08-07 Merck & Co., Inc. Eosinophil eotaxin receptor
US5939320A (en) * 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US6258527B1 (en) 1996-05-20 2001-07-10 The Aaron Diamond Aids Research Center Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
AU3375697A (en) * 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
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US6388055B1 (en) 1996-10-03 2002-05-14 Smithkline Beecham Corporation Mouse CC-CKR5 receptor polypeptide
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US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6204024B1 (en) 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
US6287805B1 (en) 1998-03-20 2001-09-11 Millennium Pharmaceuticals, Inc. Nucleic acid molecules of the protein-coupled heptahelical receptor superfamily and uses therefor
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US20080015348A1 (en) * 1998-12-16 2008-01-17 Progenics Pharmaceuticals, Inc. Nucleic acids encoding polypeptides of anti-CCR5 antibodies
US20040228869A1 (en) * 1998-12-16 2004-11-18 Progenics Pharmaceuticals, Inc. Synergistic inhibition of HIV-1 fusion and attachment, compositions and antibodies thereto
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
CA2363067C (en) 1999-01-12 2012-03-20 David J. Grainger Compounds and methods to inhibit or augment an inflammatory response
US20020048786A1 (en) * 2000-02-09 2002-04-25 Rosen Craig A. Human G-protein Chemokine Receptor HDGNR10
AU2001286519A1 (en) 2000-08-15 2002-02-25 Millennium Pharmaceuticals, Inc. Method for identifying modulators of "mec"-induced functions of ccr3 and/or ccr10
US7138119B2 (en) * 2000-09-15 2006-11-21 Progenics Pharmaceuticals, Inc. Compositions and methods for inhibition of HIV-1 infection
US7175988B2 (en) * 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
US7060273B2 (en) * 2001-04-06 2006-06-13 Progenics Pharmaceuticals, Inc. Methods for inhibiting HIV-1 infection
US20030104496A1 (en) * 2001-11-30 2003-06-05 Cytokinetics, Inc. Novel motor protein of P. falciparum and methods for its use
US7393934B2 (en) * 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
US20050069549A1 (en) 2002-01-14 2005-03-31 William Herman Targeted ligands
EP1961811B1 (de) * 2002-01-18 2010-08-25 ZymoGenetics, Inc. Zytokin Ligand zur Behandlung von Asthma und Atemwegsüberreaktivität
US7122185B2 (en) * 2002-02-22 2006-10-17 Progenics Pharmaceuticals, Inc. Anti-CCR5 antibody
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US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
AU1750497A (en) 1996-01-17 1997-08-11 Progenics Pharmaceuticals, Inc. Compounds capable of inhibiting hiv-1 infection
DE69731373T2 (de) 1996-03-01 2006-03-09 Euroscreen S.A. Cc-chemokinzeptor c-c ckr-5, dessen derivate und verwendungen
US5939320A (en) 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
AU3375697A (en) 1996-05-28 1998-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Cc chemokine receptor 5, antibodies thereto, transgenic animals
JP4183754B2 (ja) 1996-06-14 2008-11-19 プロジェニクス・ファーマスーティカルス・インコーポレーテッド Ｈｉｖ―１感染を阻害するためのケモカイン受容体の使用
US5994515A (en) * 1996-06-25 1999-11-30 Trustees Of The University Of Pennsylvania Antibodies directed against cellular coreceptors for human immunodeficiency virus and methods of using the same

Also Published As

Publication number Publication date
MX9706316A (es) 1997-11-29
US7662548B2 (en) 2010-02-16
US20050260565A1 (en) 2005-11-24
JP2001029089A (ja) 2001-02-06
ES2341371T3 (es) 2010-06-18
EP1642975A3 (de) 2006-04-12
DK1870465T3 (da) 2010-05-17
ATE458052T1 (de) 2010-03-15
BR9607300A (pt) 1997-11-25
JP2001264324A (ja) 2001-09-26
US6268477B1 (en) 2001-07-31
NO20052202D0 (no) 2005-05-04
NO973800L (no) 1997-10-20
US6797811B1 (en) 2004-09-28
NO327506B1 (no) 2009-07-27
EP0811063B9 (de) 2014-04-23
JPH11503028A (ja) 1999-03-23
EP0811063B1 (de) 2005-11-09
PL321937A1 (en) 1998-01-05
EP1642975A2 (de) 2006-04-05
US20040230037A1 (en) 2004-11-18
ES2255716T3 (es) 2006-07-01
CA2213331A1 (en) 1997-06-26
AU1689297A (en) 1997-07-14
CN1183805A (zh) 1998-06-03
ATE309349T1 (de) 2005-11-15
SK112897A3 (en) 1998-07-08
EP0811063B2 (de) 2013-12-04
EP1870465A3 (de) 2008-04-23
WO1997022698A3 (en) 1997-09-12
PL192071B1 (pl) 2006-08-31
EP1870465A2 (de) 2007-12-26
JP3288384B2 (ja) 2002-06-04
WO1997022698A2 (en) 1997-06-26
NO973800D0 (no) 1997-08-19
DE69635406T2 (de) 2006-08-03
CZ261097A3 (cs) 1998-06-17
US20080032336A1 (en) 2008-02-07
JP2009065976A (ja) 2009-04-02
DE69638128D1 (de) 2010-04-01
PL192294B1 (pl) 2006-09-29
HUP9801127A3 (en) 2000-12-28
NO20052202L (no) 1997-10-20
DE69635406T3 (de) 2014-04-24
DE69635406D1 (de) 2005-12-15
EP0811063A2 (de) 1997-12-10
US6265184B1 (en) 2001-07-24
EP1870465B1 (de) 2010-02-17
HUP9801127A2 (hu) 1998-08-28
CN1222617C (zh) 2005-10-12
CN1827646A (zh) 2006-09-06
CA2213331C (en) 2011-09-27
US20020150888A1 (en) 2002-10-17
ES2255716T5 (es) 2014-03-21
AU730463B2 (en) 2001-03-08

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