DK0809493T3 - Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser - Google Patents

Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser

Info

Publication number
DK0809493T3
DK0809493T3 DK96905555T DK96905555T DK0809493T3 DK 0809493 T3 DK0809493 T3 DK 0809493T3 DK 96905555 T DK96905555 T DK 96905555T DK 96905555 T DK96905555 T DK 96905555T DK 0809493 T3 DK0809493 T3 DK 0809493T3
Authority
DK
Denmark
Prior art keywords
treatment
topical application
skin diseases
hyperproliferative epithelial
protein cross
Prior art date
Application number
DK96905555T
Other languages
Danish (da)
English (en)
Inventor
Stuart H Yuspa
Caroline Stanwell
Terrence R Burke Jr
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of DK0809493T3 publication Critical patent/DK0809493T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK96905555T 1995-02-17 1996-02-14 Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser DK0809493T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/389,845 US5610185A (en) 1995-02-17 1995-02-17 Method for the treatment of hyperproliferative epithelial skin diseases by topical application of hydroxylated aromatic protein cross-linking compounds
PCT/US1996/002301 WO1996025159A1 (fr) 1995-02-17 1996-02-14 Procede pour traiter les lesions epitheliales hyperproliferatives de la peau par application topique de composes de reticulation de proteines aromatiques hydroxyles

Publications (1)

Publication Number Publication Date
DK0809493T3 true DK0809493T3 (da) 2002-12-23

Family

ID=23539975

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96905555T DK0809493T3 (da) 1995-02-17 1996-02-14 Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser

Country Status (11)

Country Link
US (1) US5610185A (fr)
EP (1) EP0809493B1 (fr)
JP (1) JPH11503111A (fr)
AT (1) ATE223715T1 (fr)
AU (1) AU698414B2 (fr)
CA (1) CA2212888C (fr)
DE (1) DE69623595T2 (fr)
DK (1) DK0809493T3 (fr)
ES (1) ES2183938T3 (fr)
PT (1) PT809493E (fr)
WO (1) WO1996025159A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2321307A1 (fr) 1998-02-27 1999-09-02 Venkatachala L. Narayanan Analogues de lavendustine a disubstitues et compositions pharmaceutiques contenant ces analogues
FR2778560B1 (fr) 1998-05-12 2001-06-01 Oreal Utilisation de l'acide cinnamique ou d'au moins l'un de ses derives dans une composition destinee a favoriser la desquamation de la peau, et composition le comprenant
GB2370989A (en) * 2001-01-16 2002-07-17 Btg Int Ltd Piperine analogues for the treatment of skin conditions
PT1511710E (pt) * 2002-05-31 2014-02-26 Proteotech Inc Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson
US7368593B1 (en) 2003-08-18 2008-05-06 Organics L.L.C. Method of selective esterification
US20080125485A1 (en) 2004-02-17 2008-05-29 Action Medicines Use of 2,5-Dihydroxybenzene Derivatives for Treating Actinic Keratosis
ES2238924B1 (es) 2004-02-17 2006-12-01 Investread Europa, S.L. Uso del acido 2,5-dihidroxibencenosulfonico, en la fabricacion de medicamentos de aplicacion en el tratamiento de enfermedades angiodependientes.
US20070149618A1 (en) 2004-02-17 2007-06-28 Action Medicines, S.L. Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis
WO2005092322A1 (fr) * 2004-03-29 2005-10-06 Japan Health Sciences Foundation Compose naturel provoquant une activation rar
US7351739B2 (en) * 2004-04-30 2008-04-01 Wellgen, Inc. Bioactive compounds and methods of uses thereof
FR2892923B1 (fr) * 2005-11-08 2009-01-16 Engelhard Lyon Sa Utilisatiion des derives de l'acide para-coumarique ou para- hydroxycinnamique dans des compositions cosmetiques ou dermatologiques.
US8541467B2 (en) 2006-08-16 2013-09-24 Action Medicines, S.L. Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of hematological dyscrasias and cancer of an organ
US20080114075A1 (en) 2006-08-16 2008-05-15 Action Medicines Use of 2,5-Dihydroxybenzene Derivatives for Treating Dermatitis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492815A1 (fr) * 1980-10-23 1982-04-30 Sori Soc Rech Ind Nouveau derive d'acide cinnamoyl-cinnamique, son procede de preparation et son application en therapeutique
US4925877A (en) * 1986-02-25 1990-05-15 Zaidanhojin Biseibutsu Kagaku Kenkyukai Physiologically active erbstatin analogue compounds and compositions
FR2601670B1 (fr) * 1986-07-17 1988-10-07 Cird Nouveaux derives bicycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique
JPH03109323A (ja) * 1989-09-22 1991-05-09 Microbial Chem Res Found 抗ガン剤
US5360815A (en) * 1993-06-23 1994-11-01 Merck Frosst Canada, Inc. Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis
JPH0761919A (ja) * 1993-08-26 1995-03-07 Kao Corp 美白剤

Also Published As

Publication number Publication date
CA2212888A1 (fr) 1996-08-22
EP0809493B1 (fr) 2002-09-11
DE69623595T2 (de) 2003-05-22
EP0809493A1 (fr) 1997-12-03
ES2183938T3 (es) 2003-04-01
DE69623595D1 (de) 2002-10-17
PT809493E (pt) 2003-01-31
AU698414B2 (en) 1998-10-29
CA2212888C (fr) 2006-10-17
JPH11503111A (ja) 1999-03-23
ATE223715T1 (de) 2002-09-15
US5610185A (en) 1997-03-11
WO1996025159A1 (fr) 1996-08-22
AU4928696A (en) 1996-09-04

Similar Documents

Publication Publication Date Title
DK0809493T3 (da) Fremgangsmåde til behandling af hyperproliferative epitel-hudsygdomme ved topisk tilførsel af hydroxylerede, aromatiske protein-tværbindingsforbindelser
NO973231L (no) Nye forbindelser
DE69739734D1 (de) Guanylhydrazone die nützlich sind zur behandlung von mit t-zellen verbundenen krankheiten
DE69528273D1 (de) 1,2-substituierte imidazolylverbindungen zur behandlung von entzündungen
WO1996023489A3 (fr) Utilisation de carotinoides pour preparer des medicaments destines au traitement des dermatoses
DE69510696T2 (de) 2-(2-amino-3-methoxyphenyl)-4-oxo-4h-(1)-benzopyran für die behandlung von proliferativer erkrankungen
ATE258796T1 (de) Verwendung von vitamin d4-derivaten zur behandlung von hauterkrankungen
DE69626539D1 (de) topische Verwendung von Vitamin D zur Behandlung von Augenerkrankungen
AU3142195A (en) Dermatological compositions containing benzoyl peroxide and a compound reducing skin irritation
DE69629184D1 (de) Verwendung von vitamin d2 oder vitamin d4-derivaten zur herstellung eines medikamentes zur behandlung des sekundären hyperparathyroidismus
CA2272584A1 (fr) Nouveaux derives de pyrazole substitues pour le traitement de maladies cardio-vasculaires
DE69634900D1 (de) Proteintyrosine-kinaseinhibitoren zur behandlung der osteoarthritis
MY137348A (en) Highly selective norepinephrine reuptake inhibitors and methods of using the same
ATE421329T1 (de) Verwendung von aplidine zur behandlung von kardiovaskulären erkrankungen
ATE252897T1 (de) Verwendung von p-aminophenolderivaten zur herstellung von pharmazeutischen zusammensetzungen zur behandlung von neurodegenerativen erkrankungen
AU1894895A (en) Quinazolinyl-amino derivatives having alpha-antagonist activity
DE59409394D1 (de) Therapeutisches system zur behandlung der psoriasis
ATE192923T1 (de) Verwendung von boswelliasäure zur behandlung von hirntumoren
EP0711773A4 (fr)
ATE228854T1 (de) Immunoglobuline der g-klasse zur lokalen behandlung von hautentzündungen
AU3308099A (en) Method for the treatment of pain, including chronic and female specific pain
ATE206052T1 (de) Verwendung von sphingosin-1-phosphat, sphingosin- 1-phosphat-derivaten und/oder deren gemische zur behandlung von entzündlichen hautkrankheiten
DE69400702D1 (de) N-acylpyrrolidine und arzneimittel zur behandlung oder prophylaxe von mit ckk und gastrin in zusammenhang stehenden krankheiten
ATE236630T1 (de) Verwendung von sklareolide für die behandlung von excessiven zellwachstumskrankheiten
PT865278E (pt) Utilizacao de 1-hidroxi-2-piridonas para o tratamento de doencas terapeuticamente dificeis de mucosidade da pele