DK0807173T3 - Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf - Google Patents
Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse derafInfo
- Publication number
- DK0807173T3 DK0807173T3 DK95944237T DK95944237T DK0807173T3 DK 0807173 T3 DK0807173 T3 DK 0807173T3 DK 95944237 T DK95944237 T DK 95944237T DK 95944237 T DK95944237 T DK 95944237T DK 0807173 T3 DK0807173 T3 DK 0807173T3
- Authority
- DK
- Denmark
- Prior art keywords
- immunoglobulins
- plants
- preparation
- methods
- pathogens
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36739594A | 1994-12-30 | 1994-12-30 | |
US08/434,000 US6046037A (en) | 1994-12-30 | 1995-05-04 | Method for producing immunoglobulins containing protection proteins in plants and their use |
PCT/US1995/016889 WO1996021012A1 (en) | 1994-12-30 | 1995-12-27 | Methods for producing immunoglobulins containing protection proteins in plants and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0807173T3 true DK0807173T3 (da) | 2008-01-07 |
Family
ID=27003775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95944237T DK0807173T3 (da) | 1994-12-30 | 1995-12-27 | Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf |
Country Status (11)
Country | Link |
---|---|
US (2) | US6303341B1 (de) |
EP (2) | EP1911767A3 (de) |
JP (1) | JPH11504901A (de) |
CN (1) | CN1183802A (de) |
AT (1) | ATE369423T1 (de) |
AU (1) | AU722668B2 (de) |
CA (1) | CA2208783C (de) |
DE (1) | DE69535557T2 (de) |
DK (1) | DK0807173T3 (de) |
ES (1) | ES2292173T3 (de) |
WO (1) | WO1996021012A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5959177A (en) * | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US7005560B1 (en) * | 1989-10-27 | 2006-02-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
US6808709B1 (en) | 1994-12-30 | 2004-10-26 | The Regents Of The University Of California | Immunoglobulins containing protection proteins and their use |
US5990385A (en) * | 1997-11-10 | 1999-11-23 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Protein production in transgenic alfalfa plants |
AU3115299A (en) * | 1998-03-25 | 1999-10-18 | Planet Biotechnology, Inc. | Methods and compositions for production of multimeric proteins in transgenic plants |
US7485715B2 (en) * | 1999-06-18 | 2009-02-03 | Ceres, Inc. | Sequence-determined DNA encoding AP2 domain polypeptides |
US7479555B2 (en) * | 1999-07-21 | 2009-01-20 | Ceres, Inc. | Polynucleotides having a nucleotide sequence that encodes a polypeptide having MOV34 family activity |
CA2404756A1 (en) * | 2000-03-27 | 2001-10-04 | Keith E. Mostov | Ligands directed to the non-secretory component, non-stalk region of pigr and methods of use thereof |
US20060015969A1 (en) * | 2000-04-28 | 2006-01-19 | Planet Biotechnology, Inc. | Novel immunoadhesins for treating and prventing toxicity and pathogen-mediated diseases |
CN101643512A (zh) | 2000-04-28 | 2010-02-10 | 行星生物技术有限公司 | 预防鼻病毒感染的新型免疫粘附素 |
US7304208B2 (en) | 2000-05-02 | 2007-12-04 | Ventria Bioscience | Expression of human serum albumin (HSA) in monocot seeds |
US6696620B2 (en) * | 2000-05-02 | 2004-02-24 | Epicyte Pharmaceutical, Inc. | Immunoglobulin binding protein arrays in eukaryotic cells |
EP1313506A1 (de) * | 2000-08-24 | 2003-05-28 | Washington Dental Service | Immunologische verfahren zur vorbeugung der zahnkaries |
US20040237133A1 (en) * | 2001-06-15 | 2004-11-25 | Goldman Stephen L. | Method for transformation of mono-and di-cotyledonous plants using meristematic tissue and nodal callus from dicotyledonous plants |
US20070118934A1 (en) * | 2001-10-26 | 2007-05-24 | Planet Biotechnology, Inc. | Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax |
ES2368733T3 (es) * | 2002-07-18 | 2011-11-21 | Merus B.V. | Producción recombinante de mezclas de anticuerpos. |
USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
US7476777B2 (en) * | 2002-09-17 | 2009-01-13 | Ceres, Inc. | Biological containment system |
US20050257293A1 (en) * | 2002-09-17 | 2005-11-17 | Mascia Peter N | Biological containment system |
CA2527694C (en) | 2003-05-30 | 2015-07-14 | Hendricus Renerus Jacobus Mattheus Hoogenboom | Fab library for the preparation of anti vegf and anti rabies virus fabs |
US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
US20050138692A1 (en) * | 2003-06-02 | 2005-06-23 | Biotechnology Foundation, Inc. | Production of cancer-specific antibodies in plants |
JP2007517504A (ja) * | 2003-12-09 | 2007-07-05 | ベントリア バイオサイエンス | 融合担体として種子貯蔵蛋白を利用する植物種子中の融合ポリペプチドの高水準発現 |
CA2551392A1 (en) * | 2003-12-23 | 2005-07-28 | Ventria Bioscience | Methods of expressing heterologous protein in plant seeds using monocot non seed-storage protein promoters |
EP1737971B1 (de) | 2004-01-20 | 2017-08-16 | Merus N.V. | Gemische bindender proteine |
US9758790B2 (en) | 2004-12-08 | 2017-09-12 | Ceres, Inc. | Modulating the level of components within plants |
AU2006216715A1 (en) * | 2005-02-22 | 2006-08-31 | Ceres Inc. | Modulating plant alkaloids |
WO2006115575A1 (en) * | 2005-04-20 | 2006-11-02 | Ceres Inc. | Regulatory regions from papaveraceae |
US8124839B2 (en) * | 2005-06-08 | 2012-02-28 | Ceres, Inc. | Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations |
KR101435420B1 (ko) * | 2005-08-02 | 2014-09-25 | 플래닛 바이오테크놀로지, 인코포레이티드 | 개선된 키메라 독소 수용체 단백질 및 탄저병의 예방 및치료를 위한 키메라 독소 수용체 단백질 |
US20100062137A1 (en) * | 2005-09-30 | 2010-03-11 | Steven Craig Bobzin | Modulating plant tocopherol levels |
US20090178160A1 (en) * | 2005-10-25 | 2009-07-09 | Joon-Hyun Park | Modulation of Triterpenoid Content in Plants |
US20070199090A1 (en) * | 2006-02-22 | 2007-08-23 | Nestor Apuya | Modulating alkaloid biosynthesis |
WO2007117693A2 (en) * | 2006-04-07 | 2007-10-18 | Ceres, Inc. | Regulatory protein-regulatory region associations related to alkaloid biosynthesis |
US8470308B2 (en) * | 2009-01-03 | 2013-06-25 | Ray C. Wasielewski | Enhanced medical implant comprising disrupted tooth pulp and tooth particles |
US10328103B2 (en) | 2009-01-03 | 2019-06-25 | Ray C. Wasielewski | Medical treatment composition comprising mammalian dental pulp stem cells |
MX360109B (es) | 2012-04-20 | 2018-10-23 | Merus Nv | Metodos y medios para la produccion de moleculas de tipo ig. |
CN104662044B (zh) | 2012-08-24 | 2018-10-30 | 加利福尼亚大学董事会 | 用于治疗ror1癌症并抑制转移的抗体和疫苗 |
JP6636803B2 (ja) | 2013-02-05 | 2020-01-29 | エンクマフ エスアーエールエル | Bcmaに対する抗体の選択のための方法 |
EP2762496A1 (de) | 2013-02-05 | 2014-08-06 | EngMab AG | Verfahren zur Auswahl von Antikörpern gegen BCMA |
WO2014124457A1 (en) * | 2013-02-11 | 2014-08-14 | University Of Louisville Research Foundation, Inc. | Methods for producing antibodies |
EP2789630A1 (de) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispezifische Antikörper gegen CD3e und ROR1 |
ES2850325T3 (es) | 2014-10-09 | 2021-08-27 | Engmab Sarl | Anticuerpos biespecíficos contra CD3epsilon y ROR1 |
SI3331910T1 (sl) | 2015-08-03 | 2020-07-31 | Engmab Sarl | Monoklonska protitelesa proti humani antigen dozorevanja limfocitov B (BCMA) |
AU2017289270B2 (en) | 2016-06-27 | 2023-05-04 | The Regents Of The University Of California | Cancer treatment combinations |
BR112019008426A2 (pt) | 2016-11-02 | 2019-09-03 | Engmab Sarl | anticorpo biespecífico contra bcma e cd3 e um fármaco imunológico para uso combinado no tratamento de mieloma múltiplo |
CN113875778A (zh) * | 2021-09-29 | 2022-01-04 | 季红进 | 含有植物免疫活性蛋白和5-氨基乙酰丙酸或其衍生物的生物刺激剂 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
US4443549A (en) | 1981-10-19 | 1984-04-17 | Molecular Genetics, Inc. | Production of monoclonal antibodies against bacterial adhesins |
US4652448A (en) | 1982-10-07 | 1987-03-24 | Molecular Genetics, Inc. | Use of monoclonal antibodies against bacterial adhesins |
US4870009A (en) | 1982-11-22 | 1989-09-26 | The Salk Institute For Biological Studies | Method of obtaining gene product through the generation of transgenic animals |
US5352605A (en) | 1983-01-17 | 1994-10-04 | Monsanto Company | Chimeric genes for transforming plant cells using viral promoters |
US5034322A (en) | 1983-01-17 | 1991-07-23 | Monsanto Company | Chimeric genes suitable for expression in plant cells |
GB8303994D0 (en) | 1983-02-14 | 1983-03-16 | Council Of Governors Of United | Antigenic materials |
FI68590C (fi) | 1984-03-15 | 1985-10-10 | Rosenlew Ab Oy W | Flexibel behaollare foer transport och lagring av massagods |
US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
EP0229174A1 (de) | 1985-07-16 | 1987-07-22 | The Salk Institute For Biological Studies | Genetische modifikation von pflanzen mittels retroviren |
DE3687682T2 (de) | 1985-08-07 | 1993-08-19 | Monsanto Co | Glyphosat resistente pflanzen. |
US5352446A (en) | 1986-03-25 | 1994-10-04 | Council Of Governors Of The United Medical And Dental Schools Of Guy's And St. Thomas's Hospitals | Method of treating dental caries with monoclonal antibodies against the antigen I and antigen I/II of streptococcus mutans |
GB8704648D0 (en) | 1987-02-27 | 1987-04-01 | Guy S & St Thomas S Hospitals | Antibodies |
US5352440A (en) | 1988-03-30 | 1994-10-04 | Trustees Of Boston University | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof |
ATE126005T1 (de) | 1988-04-25 | 1995-08-15 | Monsanto Co | Insektenresistente salatpflanzen. |
US5183756A (en) | 1988-08-19 | 1993-02-02 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibody (D612) having selective reactivity for gastrointestinal caricinomas and method for employing the same |
CA2016842A1 (en) | 1989-05-16 | 1990-11-16 | Richard A. Lerner | Method for tapping the immunological repertoire |
US5202422A (en) * | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
CN1057785A (zh) * | 1990-04-16 | 1992-01-15 | 哈佛大学校长及研究员协会 | 合成多聚免疫球蛋白受体,受体-抗体复合物,生产及应用 |
JPH04169539A (ja) | 1990-11-01 | 1992-06-17 | Imuno Japan:Kk | 消化器疾患治療・予防剤およびその製造方法 |
-
1995
- 1995-12-27 CN CN95197699A patent/CN1183802A/zh active Pending
- 1995-12-27 AT AT95944237T patent/ATE369423T1/de active
- 1995-12-27 EP EP07113307A patent/EP1911767A3/de not_active Withdrawn
- 1995-12-27 EP EP95944237A patent/EP0807173B1/de not_active Expired - Lifetime
- 1995-12-27 DK DK95944237T patent/DK0807173T3/da active
- 1995-12-27 CA CA2208783A patent/CA2208783C/en not_active Expired - Fee Related
- 1995-12-27 WO PCT/US1995/016889 patent/WO1996021012A1/en active IP Right Grant
- 1995-12-27 DE DE69535557T patent/DE69535557T2/de not_active Expired - Lifetime
- 1995-12-27 AU AU46088/96A patent/AU722668B2/en not_active Ceased
- 1995-12-27 JP JP8521124A patent/JPH11504901A/ja not_active Withdrawn
- 1995-12-27 ES ES95944237T patent/ES2292173T3/es not_active Expired - Lifetime
-
1999
- 1999-05-14 US US09/312,157 patent/US6303341B1/en not_active Expired - Fee Related
-
2001
- 2001-10-16 US US09/982,107 patent/US20020159958A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2208783C (en) | 2010-09-28 |
DE69535557T2 (de) | 2008-04-30 |
JPH11504901A (ja) | 1999-05-11 |
AU4608896A (en) | 1996-07-24 |
ES2292173T3 (es) | 2008-03-01 |
ATE369423T1 (de) | 2007-08-15 |
DE69535557D1 (de) | 2007-09-20 |
EP1911767A2 (de) | 2008-04-16 |
WO1996021012A1 (en) | 1996-07-11 |
AU722668B2 (en) | 2000-08-10 |
CA2208783A1 (en) | 1996-07-11 |
CN1183802A (zh) | 1998-06-03 |
EP0807173B1 (de) | 2007-08-08 |
US6303341B1 (en) | 2001-10-16 |
US20020159958A1 (en) | 2002-10-31 |
EP1911767A3 (de) | 2008-09-10 |
EP0807173A1 (de) | 1997-11-19 |
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