DK0807173T3 - Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf - Google Patents

Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf

Info

Publication number
DK0807173T3
DK0807173T3 DK95944237T DK95944237T DK0807173T3 DK 0807173 T3 DK0807173 T3 DK 0807173T3 DK 95944237 T DK95944237 T DK 95944237T DK 95944237 T DK95944237 T DK 95944237T DK 0807173 T3 DK0807173 T3 DK 0807173T3
Authority
DK
Denmark
Prior art keywords
immunoglobulins
plants
preparation
methods
pathogens
Prior art date
Application number
DK95944237T
Other languages
Danish (da)
English (en)
Inventor
Andrew C Hiatt
Julian K-C Ma
Thomas Lehner
Keith E Mostov
Original Assignee
Univ California
Planet Biotechnology Inc
King S College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/434,000 external-priority patent/US6046037A/en
Application filed by Univ California, Planet Biotechnology Inc, King S College London filed Critical Univ California
Application granted granted Critical
Publication of DK0807173T3 publication Critical patent/DK0807173T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
DK95944237T 1994-12-30 1995-12-27 Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf DK0807173T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36739594A 1994-12-30 1994-12-30
US08/434,000 US6046037A (en) 1994-12-30 1995-05-04 Method for producing immunoglobulins containing protection proteins in plants and their use
PCT/US1995/016889 WO1996021012A1 (en) 1994-12-30 1995-12-27 Methods for producing immunoglobulins containing protection proteins in plants and their use

Publications (1)

Publication Number Publication Date
DK0807173T3 true DK0807173T3 (da) 2008-01-07

Family

ID=27003775

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95944237T DK0807173T3 (da) 1994-12-30 1995-12-27 Fremgangsmåder til fremstilling af immunoglobuliner indeholdende beskyttelsesproteiner i planter og anvendelse deraf

Country Status (11)

Country Link
US (2) US6303341B1 (de)
EP (2) EP1911767A3 (de)
JP (1) JPH11504901A (de)
CN (1) CN1183802A (de)
AT (1) ATE369423T1 (de)
AU (1) AU722668B2 (de)
CA (1) CA2208783C (de)
DE (1) DE69535557T2 (de)
DK (1) DK0807173T3 (de)
ES (1) ES2292173T3 (de)
WO (1) WO1996021012A1 (de)

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US6808709B1 (en) 1994-12-30 2004-10-26 The Regents Of The University Of California Immunoglobulins containing protection proteins and their use
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US20060015969A1 (en) * 2000-04-28 2006-01-19 Planet Biotechnology, Inc. Novel immunoadhesins for treating and prventing toxicity and pathogen-mediated diseases
DE60139864D1 (de) 2000-04-28 2009-10-22 Planet Biotechnology Inc Immunoadhesin zur impfung gegen rhinovirus
US6696620B2 (en) * 2000-05-02 2004-02-24 Epicyte Pharmaceutical, Inc. Immunoglobulin binding protein arrays in eukaryotic cells
US7304208B2 (en) * 2000-05-02 2007-12-04 Ventria Bioscience Expression of human serum albumin (HSA) in monocot seeds
AU2000270698A1 (en) * 2000-08-24 2002-03-04 Regents Of The Universtiy Of California Immunologic method for the prevention of dental caries
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US20070118934A1 (en) * 2001-10-26 2007-05-24 Planet Biotechnology, Inc. Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
CA2872136C (en) * 2002-07-18 2017-06-20 Merus B.V. Recombinant production of mixtures of antibodies
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WO2004027038A2 (en) * 2002-09-17 2004-04-01 Ceres, Inc. Biological containment system
CA2527694C (en) * 2003-05-30 2015-07-14 Hendricus Renerus Jacobus Mattheus Hoogenboom Fab library for the preparation of anti vegf and anti rabies virus fabs
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
US20050138692A1 (en) * 2003-06-02 2005-06-23 Biotechnology Foundation, Inc. Production of cancer-specific antibodies in plants
WO2005056578A2 (en) * 2003-12-09 2005-06-23 Ventria Bioscience High-level expression of fusion polypeptides in plant seeds utilizing seed-storage proteins as fusion carriers
AU2003297781A1 (en) * 2003-12-23 2005-08-03 Ventria Bioscience Methods of expressing heterologous protein in plant seeds using monocot non seed-storage protein promoters
EP1737971B1 (de) 2004-01-20 2017-08-16 Merus N.V. Gemische bindender proteine
US9758790B2 (en) 2004-12-08 2017-09-12 Ceres, Inc. Modulating the level of components within plants
WO2007050625A1 (en) * 2005-10-25 2007-05-03 Ceres, Inc. Modulation of triterpenoid content in plants
CA2598436A1 (en) * 2005-02-22 2006-08-31 Ceres, Inc. Modulating plant alkaloids
US7312376B2 (en) * 2005-04-20 2007-12-25 Ceres, Inc. Regulatory regions from Papaveraceae
WO2006133461A1 (en) * 2005-06-08 2006-12-14 Ceres Inc. Identification of terpenoid-biosynthesis related regulatory protein-regulatory region associations
CA2617877A1 (en) * 2005-08-02 2007-04-19 Planet Biotechnology, Inc. Improved chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax
WO2007041536A2 (en) * 2005-09-30 2007-04-12 Ceres, Inc. Modulating plant tocopherol levels
US20070199090A1 (en) * 2006-02-22 2007-08-23 Nestor Apuya Modulating alkaloid biosynthesis
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US10328103B2 (en) 2009-01-03 2019-06-25 Ray C. Wasielewski Medical treatment composition comprising mammalian dental pulp stem cells
US8470308B2 (en) * 2009-01-03 2013-06-25 Ray C. Wasielewski Enhanced medical implant comprising disrupted tooth pulp and tooth particles
ES2743399T3 (es) 2012-04-20 2020-02-19 Merus Nv Métodos y medios para la producción de moléculas heterodiméricas similares a Ig
EP2888283B1 (de) 2012-08-24 2018-09-19 The Regents of The University of California Antikörper und impfstoffe zur verwendung bei der behandlung von ror1-krebsarten und zur metastasenhemmung
EP2953974B1 (de) 2013-02-05 2017-12-20 EngMab Sàrl Bispezifische antikörper gegen cd3 und bcma
EP2762496A1 (de) 2013-02-05 2014-08-06 EngMab AG Verfahren zur Auswahl von Antikörpern gegen BCMA
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EP2789630A1 (de) 2013-04-09 2014-10-15 EngMab AG Bispezifische Antikörper gegen CD3e und ROR1
JP6708635B2 (ja) 2014-10-09 2020-06-10 エンクマフ エスアーエールエル ＣＤ３εおよびＲＯＲ１に対する二特異性抗体
BR112018001955B1 (pt) 2015-08-03 2021-05-11 Engmab Sárl anticorpo monoclonal que se liga às células b humanas (bcma), composição farmacêutica e seu uso
US10688181B2 (en) 2016-06-27 2020-06-23 The Regents Of The University Of California Cancer treatment combinations
CN110167964B (zh) 2016-11-02 2023-12-01 百时美施贵宝公司 组合用于治疗多发性骨髓瘤的针对bcma和cd3的双特异性抗体和免疫药物
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CN113875778A (zh) * 2021-09-29 2022-01-04 季红进 含有植物免疫活性蛋白和5-氨基乙酰丙酸或其衍生物的生物刺激剂

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Also Published As

Publication number Publication date
US20020159958A1 (en) 2002-10-31
US6303341B1 (en) 2001-10-16
DE69535557D1 (de) 2007-09-20
EP0807173A1 (de) 1997-11-19
AU722668B2 (en) 2000-08-10
EP1911767A2 (de) 2008-04-16
ATE369423T1 (de) 2007-08-15
CA2208783A1 (en) 1996-07-11
DE69535557T2 (de) 2008-04-30
JPH11504901A (ja) 1999-05-11
AU4608896A (en) 1996-07-24
WO1996021012A1 (en) 1996-07-11
CA2208783C (en) 2010-09-28
EP1911767A3 (de) 2008-09-10
CN1183802A (zh) 1998-06-03
EP0807173B1 (de) 2007-08-08
ES2292173T3 (es) 2008-03-01

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