DK0785932T3 - Pyrrolyl-tetrahydrobenzoquinoxalindioner, deres fremstilling og anvendelse som glutamatreceptor-antagonister - Google Patents

Pyrrolyl-tetrahydrobenzoquinoxalindioner, deres fremstilling og anvendelse som glutamatreceptor-antagonister

Info

Publication number
DK0785932T3
DK0785932T3 DK95935894T DK95935894T DK0785932T3 DK 0785932 T3 DK0785932 T3 DK 0785932T3 DK 95935894 T DK95935894 T DK 95935894T DK 95935894 T DK95935894 T DK 95935894T DK 0785932 T3 DK0785932 T3 DK 0785932T3
Authority
DK
Denmark
Prior art keywords
pct
preparation
glutamate receptor
tetrahydrobenzoquinoxalinediones
pyrrolyl
Prior art date
Application number
DK95935894T
Other languages
Danish (da)
English (en)
Inventor
Hans Peter Hofmann
Berthold Behl
Wilfried Lubisch
Michael Vierling
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK0785932T3 publication Critical patent/DK0785932T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK95935894T 1994-10-14 1995-10-02 Pyrrolyl-tetrahydrobenzoquinoxalindioner, deres fremstilling og anvendelse som glutamatreceptor-antagonister DK0785932T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4436852A DE4436852A1 (de) 1994-10-14 1994-10-14 Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
PCT/EP1995/003902 WO1996011922A1 (de) 1994-10-14 1995-10-02 Pyrrolyl-tetrahydrobenzochinoxalindione, ihre herstellung und verwendung als glutamatrezeptor-antagonisten

Publications (1)

Publication Number Publication Date
DK0785932T3 true DK0785932T3 (da) 2000-05-01

Family

ID=6530834

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95935894T DK0785932T3 (da) 1994-10-14 1995-10-02 Pyrrolyl-tetrahydrobenzoquinoxalindioner, deres fremstilling og anvendelse som glutamatreceptor-antagonister

Country Status (20)

Country Link
US (1) US5849744A (no)
EP (1) EP0785932B1 (no)
JP (1) JPH10507186A (no)
KR (1) KR970707117A (no)
CN (1) CN1078208C (no)
AT (1) ATE188214T1 (no)
AU (1) AU3803495A (no)
BG (1) BG101407A (no)
BR (1) BR9509337A (no)
CA (1) CA2201527A1 (no)
CZ (1) CZ113197A3 (no)
DE (2) DE4436852A1 (no)
DK (1) DK0785932T3 (no)
FI (1) FI971528A (no)
IL (1) IL115625A0 (no)
MX (1) MX9702659A (no)
NO (1) NO971674L (no)
PL (1) PL319660A1 (no)
WO (1) WO1996011922A1 (no)
ZA (1) ZA958643B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19532050A1 (de) * 1995-08-31 1997-03-06 Basf Ag Pyrrolyl-tetrahydrochinoxalindione, ihre Herstellung und Verwendung zur Bekämpfung von Krankheiten
AU3571997A (en) * 1996-08-01 1998-02-25 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
GB2346883B (en) * 1996-09-02 2001-02-14 Lilly Industries Ltd GluR5 receptor binding assay
CN1298704C (zh) * 2000-01-24 2007-02-07 神经研究公司 具有神经营养活性的靛红衍生物
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US488955A (en) * 1892-12-27 Hedge-fence trainer
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
EP0556393B1 (en) * 1990-11-06 2000-07-26 Yamanouchi Pharmaceutical Co. Ltd. Fused pyrazine derivative
DE4135871A1 (de) * 1991-10-26 1993-04-29 Schering Ag Chinoxalinderivate, deren herstellung und verwendung in arzneimitteln
JPH069382A (ja) * 1992-04-17 1994-01-18 Takeda Chem Ind Ltd 安定化された固型製剤およびその製造方法
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones

Also Published As

Publication number Publication date
IL115625A0 (en) 1996-01-19
MX9702659A (es) 1997-06-28
CN1160400A (zh) 1997-09-24
FI971528A0 (fi) 1997-04-11
BG101407A (en) 1997-09-30
KR970707117A (ko) 1997-12-01
NO971674L (no) 1997-06-11
EP0785932B1 (de) 1999-12-29
CZ113197A3 (cs) 1998-03-18
DE59507539D1 (de) 2000-02-03
AU3803495A (en) 1996-05-06
EP0785932A1 (de) 1997-07-30
JPH10507186A (ja) 1998-07-14
US5849744A (en) 1998-12-15
DE4436852A1 (de) 1996-04-18
CA2201527A1 (en) 1996-04-25
BR9509337A (pt) 1998-01-27
PL319660A1 (en) 1997-08-18
CN1078208C (zh) 2002-01-23
NO971674D0 (no) 1997-04-11
ZA958643B (en) 1997-04-14
WO1996011922A1 (de) 1996-04-25
ATE188214T1 (de) 2000-01-15
FI971528A (fi) 1997-04-11

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