MX9702659A - Pirroliltetrahidrobenzoquinoxalindionas, su preparacion y uso. - Google Patents

Pirroliltetrahidrobenzoquinoxalindionas, su preparacion y uso.

Info

Publication number
MX9702659A
MX9702659A MX9702659A MX9702659A MX9702659A MX 9702659 A MX9702659 A MX 9702659A MX 9702659 A MX9702659 A MX 9702659A MX 9702659 A MX9702659 A MX 9702659A MX 9702659 A MX9702659 A MX 9702659A
Authority
MX
Mexico
Prior art keywords
preparation
tetrahydrobenzoquinoxaline
diones
pyrrolyl
receptor antagonists
Prior art date
Application number
MX9702659A
Other languages
English (en)
Other versions
MXPA97002659A (es
Inventor
Wilfried Lubisch
Michael Vierling
Berthold Behl
Hans Peter Hofmann
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MXPA97002659A publication Critical patent/MXPA97002659A/es
Publication of MX9702659A publication Critical patent/MX9702659A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se describen pirroliltetrahidrobenzoquinoxalindionas de la formula I y sus formas tautoméricas e isoméricas, y sus sales fisiologicamente toleradas, en donde las variables tienen los significados establecidos en la descripcion, y la preparacion de las mismas. Los compuestos novedosos son adecuados para controlar enfermedades.
MX9702659A 1994-10-14 1995-10-02 Pirroliltetrahidrobenzoquinoxalindionas, su preparacion y uso. MX9702659A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4436852.6 1994-10-14
DE4436852A DE4436852A1 (de) 1994-10-14 1994-10-14 Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
PCT/EP1995/003902 WO1996011922A1 (de) 1994-10-14 1995-10-02 Pyrrolyl-tetrahydrobenzochinoxalindione, ihre herstellung und verwendung als glutamatrezeptor-antagonisten

Publications (2)

Publication Number Publication Date
MXPA97002659A MXPA97002659A (es) 1997-06-01
MX9702659A true MX9702659A (es) 1997-06-28

Family

ID=6530834

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9702659A MX9702659A (es) 1994-10-14 1995-10-02 Pirroliltetrahidrobenzoquinoxalindionas, su preparacion y uso.

Country Status (20)

Country Link
US (1) US5849744A (es)
EP (1) EP0785932B1 (es)
JP (1) JPH10507186A (es)
KR (1) KR970707117A (es)
CN (1) CN1078208C (es)
AT (1) ATE188214T1 (es)
AU (1) AU3803495A (es)
BG (1) BG101407A (es)
BR (1) BR9509337A (es)
CA (1) CA2201527A1 (es)
CZ (1) CZ113197A3 (es)
DE (2) DE4436852A1 (es)
DK (1) DK0785932T3 (es)
FI (1) FI971528L (es)
IL (1) IL115625A0 (es)
MX (1) MX9702659A (es)
NO (1) NO971674L (es)
PL (1) PL319660A1 (es)
WO (1) WO1996011922A1 (es)
ZA (1) ZA958643B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19532050A1 (de) * 1995-08-31 1997-03-06 Basf Ag Pyrrolyl-tetrahydrochinoxalindione, ihre Herstellung und Verwendung zur Bekämpfung von Krankheiten
WO1998005651A1 (en) * 1996-08-01 1998-02-12 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
GB2316616A (en) * 1996-09-02 1998-03-04 Lilly Industries Ltd Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders
JP2003520851A (ja) * 2000-01-24 2003-07-08 ニューロサーチ、アクティーゼルスカブ 神経栄養活性を有するイサチン誘導体
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US488955A (en) * 1892-12-27 Hedge-fence trainer
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
CA2095444C (en) * 1990-11-06 2001-06-19 Shuichi Sakamoto Fused pyrazine derivatives
DE4135871A1 (de) * 1991-10-26 1993-04-29 Schering Ag Chinoxalinderivate, deren herstellung und verwendung in arzneimitteln
JPH069382A (ja) * 1992-04-17 1994-01-18 Takeda Chem Ind Ltd 安定化された固型製剤およびその製造方法
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones

Also Published As

Publication number Publication date
IL115625A0 (en) 1996-01-19
WO1996011922A1 (de) 1996-04-25
FI971528A0 (fi) 1997-04-11
NO971674L (no) 1997-06-11
ATE188214T1 (de) 2000-01-15
CA2201527A1 (en) 1996-04-25
US5849744A (en) 1998-12-15
EP0785932A1 (de) 1997-07-30
BG101407A (bg) 1997-09-30
BR9509337A (pt) 1998-01-27
ZA958643B (en) 1997-04-14
EP0785932B1 (de) 1999-12-29
NO971674D0 (no) 1997-04-11
KR970707117A (ko) 1997-12-01
JPH10507186A (ja) 1998-07-14
DE4436852A1 (de) 1996-04-18
AU3803495A (en) 1996-05-06
FI971528A7 (fi) 1997-04-11
CN1160400A (zh) 1997-09-24
CZ113197A3 (cs) 1998-03-18
PL319660A1 (en) 1997-08-18
FI971528L (fi) 1997-04-11
DK0785932T3 (da) 2000-05-01
DE59507539D1 (de) 2000-02-03
CN1078208C (zh) 2002-01-23

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