DK0775745T3 - Cathepsin G-inhiberende aptamerer - Google Patents
Cathepsin G-inhiberende aptamererInfo
- Publication number
- DK0775745T3 DK0775745T3 DK96118661T DK96118661T DK0775745T3 DK 0775745 T3 DK0775745 T3 DK 0775745T3 DK 96118661 T DK96118661 T DK 96118661T DK 96118661 T DK96118661 T DK 96118661T DK 0775745 T3 DK0775745 T3 DK 0775745T3
- Authority
- DK
- Denmark
- Prior art keywords
- cathepsin
- aptamers
- inhibitory aptamers
- nucleotides
- inhibitory
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19543750A DE19543750C2 (de) | 1995-11-24 | 1995-11-24 | Cathepsin G inhibierende Aptamere |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0775745T3 true DK0775745T3 (da) | 2004-06-01 |
Family
ID=7778263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96118661T DK0775745T3 (da) | 1995-11-24 | 1996-11-21 | Cathepsin G-inhiberende aptamerer |
Country Status (8)
Country | Link |
---|---|
US (1) | US5780449A (de) |
EP (1) | EP0775745B1 (de) |
JP (1) | JP4257939B2 (de) |
AT (1) | ATE258597T1 (de) |
DE (2) | DE19543750C2 (de) |
DK (1) | DK0775745T3 (de) |
ES (1) | ES2217297T3 (de) |
PT (1) | PT775745E (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6682886B1 (en) * | 1994-04-28 | 2004-01-27 | Gilead Sciences, Inc. | Bivalent binding molecules of 7 transmembrane G protein-coupled receptors |
AU3363399A (en) * | 1998-03-27 | 1999-10-18 | President And Fellows Of Harvard College | Aptamer based bacterial inhibition systems (abbis) |
US6458559B1 (en) | 1998-04-22 | 2002-10-01 | Cornell Research Foundation, Inc. | Multivalent RNA aptamers and their expression in multicellular organisms |
DE19916417A1 (de) * | 1999-04-01 | 2000-10-19 | Schering Ag | Amyloidspezifisches Aptamer |
EP1330544A4 (de) | 2000-09-26 | 2005-04-06 | Univ Duke | Rna-aptamere und verfahren zu deren identifizierung |
US7300922B2 (en) * | 2001-05-25 | 2007-11-27 | Duke University | Modulators of pharmacological agents |
US20040023415A1 (en) * | 2002-03-05 | 2004-02-05 | Konstantin Sokolov | Biospecific contrast agents |
WO2004001065A2 (en) | 2002-06-24 | 2003-12-31 | Cornell Research Foundation, Inc. | Exhaustive selection or rna aptamers against complex targets |
US20070003975A1 (en) * | 2003-05-02 | 2007-01-04 | Canon Kabushiki Kaisha | Structured construct and producing method therefor |
EP1493810A1 (de) * | 2003-06-30 | 2005-01-05 | Gentium S.p.A. | Auf DNA-basierte Aptamere für Cathepsin G |
JP4533044B2 (ja) * | 2003-08-27 | 2010-08-25 | キヤノン株式会社 | センサ |
DK1745062T3 (da) * | 2004-04-22 | 2014-08-11 | Regado Biosciences Inc | Forbedrede modulatorer af koagulationsfaktorer |
CA2567156A1 (en) * | 2004-05-17 | 2006-07-20 | Cambrios Technology Corp. | Biofabrication of transistors including field effect transistors |
EP2268664B1 (de) * | 2007-12-03 | 2017-05-24 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Doc1-zusammensetzungen und verfahren zur behandlung von krebs |
US20100018674A1 (en) * | 2008-07-22 | 2010-01-28 | Donald John Enzinna | Reservoir with moveable partition for quick recovery |
JP7120531B2 (ja) * | 2018-02-12 | 2022-08-17 | アプタキュア セラピューティクス リミテッド | スクレロスチンに対するアプタマー及びその使用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5217951A (en) * | 1986-12-24 | 1993-06-08 | John Lezdey | Treatment of inflammation |
US5290762A (en) * | 1986-12-24 | 1994-03-01 | John Lezdey | Treatment of inflammation |
US5612194A (en) * | 1989-06-23 | 1997-03-18 | Trustees Of The University Of Pennsylvania | Methods of producing effective recombinant serine protease inhibitors and uses of these inhibitors |
WO1991019813A1 (en) * | 1990-06-11 | 1991-12-26 | The University Of Colorado Foundation, Inc. | Nucleic acid ligands |
AU1435492A (en) * | 1991-02-21 | 1992-09-15 | Gilead Sciences, Inc. | Aptamer specific for biomolecules and method of making |
DE69229552T2 (de) * | 1991-05-23 | 1999-12-23 | Merrell Pharma Inc | Hemmstoffe für kathepsin-g und elastase zur verhütung von bindegewebsabbau |
US5514694A (en) * | 1992-09-21 | 1996-05-07 | Georgia Tech Research Corp | Peptidyl ketoamides |
-
1995
- 1995-11-24 DE DE19543750A patent/DE19543750C2/de not_active Expired - Fee Related
-
1996
- 1996-11-19 US US08/753,054 patent/US5780449A/en not_active Expired - Lifetime
- 1996-11-21 DE DE69631409T patent/DE69631409T2/de not_active Expired - Lifetime
- 1996-11-21 AT AT96118661T patent/ATE258597T1/de active
- 1996-11-21 DK DK96118661T patent/DK0775745T3/da active
- 1996-11-21 ES ES96118661T patent/ES2217297T3/es not_active Expired - Lifetime
- 1996-11-21 EP EP96118661A patent/EP0775745B1/de not_active Expired - Lifetime
- 1996-11-21 PT PT96118661T patent/PT775745E/pt unknown
- 1996-11-25 JP JP32916996A patent/JP4257939B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE19543750A1 (de) | 1997-07-03 |
EP0775745B1 (de) | 2004-01-28 |
DE19543750C2 (de) | 1997-10-23 |
US5780449A (en) | 1998-07-14 |
DE69631409T2 (de) | 2004-12-02 |
JPH09216895A (ja) | 1997-08-19 |
ES2217297T3 (es) | 2004-11-01 |
JP4257939B2 (ja) | 2009-04-30 |
DE69631409D1 (de) | 2004-03-04 |
PT775745E (pt) | 2004-06-30 |
ATE258597T1 (de) | 2004-02-15 |
EP0775745A2 (de) | 1997-05-28 |
EP0775745A3 (de) | 1999-10-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0775745T3 (da) | Cathepsin G-inhiberende aptamerer | |
DK0691980T3 (da) | 7-deazapurinmodifiderende oligonukleotider | |
ATE460481T1 (de) | Verfahren zur hemmung der expression eines zielgens und medikament zur therapie einer tumorerkrankung | |
RU97120584A (ru) | Ингибитор активности il-6 | |
ATE345115T1 (de) | Zusammensetzungen zur behandlung von chlamydiale assozierten krankheiten | |
FI946201A (fi) | Itsestabiloidut oligonukleotidit terapeuttisina aineina | |
FI972935A0 (fi) | Kalpaiinin ja/tai katepsiini B:n substituoituja oksatsolidiiniestäjiä | |
BR9708114A (pt) | Análogos xantona para o tratamento de doenças infecciosas. | |
TR200002921T2 (tr) | Yarı-Sentetik ekteinasidinler | |
DE69328025T2 (de) | Dorsalgewebe beeinflussender faktor und zusammensetzungen | |
WO2001032832A3 (en) | Antisense inhibition of nucleolin expression | |
PT932613E (pt) | Expressao de bloqueio de factoes de virulencia em s. aureus | |
DE60042585D1 (de) | 3-Aza-6,8-dioxabicycloÄ3.2.1Üoctane und Analoga sowie diese enthaltende kombinatorische Bibliotheken | |
HUP9802423A2 (hu) | Hiperproliferatív megbetegedések kombinált gyógyászati kezelése | |
PT804465E (pt) | Novos inibidores da elastase | |
NO980296D0 (no) | Forbedrede terapeutiske midler | |
ATE160354T1 (de) | Oligonukleotide mit anti-cytomegalovirus wirkung | |
ITTO940379A0 (it) | Sequenze specifiche per il dna umano. | |
TR199700863A3 (tr) | Paklitaksel hazirlama prosesi. | |
신동희 | The Concept of Finding Aids | |
BR0016347A (pt) | Oligonucleotìdios antisenso | |
NL1001157A1 (nl) | Zuiveringsinstallatie. | |
KR970016336U (ko) | 오,폐수처리장의 탈취장치 | |
ZA991402B (en) | Genes for activation of plant pathogen defense systems. | |
UA25164A (uk) | Спосіб оперативhого лікуваhhя косоокості по в.і. ємчеhку |