DK0768870T3 - Multipel indkapsling af oleofile substanser - Google Patents

Multipel indkapsling af oleofile substanser

Info

Publication number
DK0768870T3
DK0768870T3 DK95924932T DK95924932T DK0768870T3 DK 0768870 T3 DK0768870 T3 DK 0768870T3 DK 95924932 T DK95924932 T DK 95924932T DK 95924932 T DK95924932 T DK 95924932T DK 0768870 T3 DK0768870 T3 DK 0768870T3
Authority
DK
Denmark
Prior art keywords
polymer
oleophilic
cross
oleophilic substance
multiple encapsulation
Prior art date
Application number
DK95924932T
Other languages
English (en)
Inventor
Stasia Boyle
Kuei-Tu Chang
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0768870T3 publication Critical patent/DK0768870T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Fodder In General (AREA)
DK95924932T 1994-07-01 1995-06-24 Multipel indkapsling af oleofile substanser DK0768870T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26972094A 1994-07-01 1994-07-01
US08/439,787 US5938990A (en) 1994-07-01 1995-05-24 Encapsulation of oleophilic substances and compositions produced thereby
PCT/EP1995/002468 WO1996001103A1 (en) 1994-07-01 1995-06-24 Multiple encapsulation of oleophilic substances

Publications (1)

Publication Number Publication Date
DK0768870T3 true DK0768870T3 (da) 2001-02-05

Family

ID=26953853

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95924932T DK0768870T3 (da) 1994-07-01 1995-06-24 Multipel indkapsling af oleofile substanser

Country Status (10)

Country Link
US (5) US5938990A (da)
EP (1) EP0768870B1 (da)
JP (1) JPH10502621A (da)
KR (1) KR100392215B1 (da)
CN (1) CN1141935C (da)
AT (1) ATE197397T1 (da)
DE (1) DE69519378T2 (da)
DK (1) DK0768870T3 (da)
ES (1) ES2152409T3 (da)
WO (1) WO1996001103A1 (da)

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US5938990A (en) * 1994-07-01 1999-08-17 Roche Vitamins Inc. Encapsulation of oleophilic substances and compositions produced thereby
TW367247B (en) * 1998-02-03 1999-08-21 Otsuka Pharma Co Ltd Storage container for Vitamin D solution and transfusion container
US6303167B1 (en) * 1998-11-09 2001-10-16 Archer-Daniels-Midland Company Method of producing vitamin powders
US6770572B1 (en) 1999-01-26 2004-08-03 Alliedsignal Inc. Use of multifunctional si-based oligomer/polymer for the surface modification of nanoporous silica films
US6914073B2 (en) * 1999-03-18 2005-07-05 Bristol Myers Squibb Company Vitamin formulation for cardiovascular health
DK1106174T4 (da) * 1999-12-09 2017-01-23 Dsm Ip Assets Bv Sammensætninger indeholdende fedt-opløselige vitaminer
ES2238963T5 (es) 1999-12-09 2017-04-04 Dsm Ip Assets B.V. Composiciones que contienen vitaminas solubles en grasas
JP2001219487A (ja) * 2000-02-10 2001-08-14 Mitsubishi Heavy Ind Ltd 紙製品の製造方法及び製造装置並びに紙接合用糊及び紙接合用糊のマイクロカプセル製造方法
US8178150B2 (en) 2000-02-22 2012-05-15 Suzanne Jaffe Stillman Water containing soluble fiber
US7892586B2 (en) 2001-02-22 2011-02-22 Suzanne Jaffe Stillman Water containing soluble fiber
CA2423484A1 (en) 2000-09-27 2002-04-04 Verion Inc. Instant water dissolvable encapsulate and process
KR100439068B1 (ko) * 2001-09-07 2004-07-05 주식회사 코리아나화장품 레티놀을 3중으로 안정화한 화장료
US7442227B2 (en) * 2001-10-09 2008-10-28 Washington Unniversity Tightly agglomerated non-oxide particles and method for producing the same
EP1455594B2 (en) † 2001-12-20 2015-07-22 Société des Produits Nestlé S.A. A food product containing gel capsules or tablets
US6974592B2 (en) † 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
US20040033903A1 (en) * 2002-05-02 2004-02-19 Volker Kuellmer Coated, agglomerated phytochemicals
WO2004008872A2 (en) 2002-07-23 2004-01-29 Wm. Wrigley Jr. Company Encapsulated flavors and chewing gum using same
US20040115226A1 (en) * 2002-12-12 2004-06-17 Wenji Li Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same
US20050214367A1 (en) * 2004-03-22 2005-09-29 Volker Kuellmer Processes for making coated phytochemicals and tocopherols and products formed therefrom
WO2005105040A2 (en) * 2004-04-26 2005-11-10 Micelle Products, Inc. Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications
US8075910B2 (en) * 2004-05-20 2011-12-13 Pbm Pharmaceuticals, Inc. Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions
DE102004036437A1 (de) * 2004-07-27 2006-03-23 Röhm GmbH & Co. KG Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
JP2009517482A (ja) * 2005-11-28 2009-04-30 ユーエス・ニュートラシューティカルズ・エルエルシー・ディービーエイ・ヴァレンサ・インターナショナル 藻類及び藻類抽出物の栄養補助組成物
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
GB201102557D0 (en) * 2011-02-14 2011-03-30 Univ Nottingham Oil bodies
US11696594B2 (en) * 2015-12-10 2023-07-11 Dsm Ip Assets B.V. Vitamin formulation
CN112641121B (zh) * 2020-10-10 2022-04-19 广州玖洲胶囊生物科技有限公司 一种羟丙甲基纤维素和卡拉胶的填充空心胶囊制备方法
CN112753778A (zh) * 2020-12-31 2021-05-07 大连臻鼎科技有限责任公司 一种高稳定性油脂微粒制品及其制备方法

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US4537783A (en) * 1983-04-20 1985-08-27 The Procter & Gamble Company Control of particle size distribution during continuous heat-setting of meat analog
US4670247A (en) * 1983-07-05 1987-06-02 Hoffman-Laroche Inc. Process for preparing fat-soluble vitamin active beadlets
DE3586600T2 (de) * 1984-02-10 1993-02-18 Benzon Pharma As Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend.
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
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US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
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ES2068762B1 (es) * 1993-07-21 1995-12-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion.
US5938990A (en) * 1994-07-01 1999-08-17 Roche Vitamins Inc. Encapsulation of oleophilic substances and compositions produced thereby

Also Published As

Publication number Publication date
US5925381A (en) 1999-07-20
EP0768870B1 (en) 2000-11-08
US5938990A (en) 1999-08-17
ATE197397T1 (de) 2000-11-11
ES2152409T3 (es) 2001-02-01
CN1151694A (zh) 1997-06-11
US6001554A (en) 1999-12-14
CN1141935C (zh) 2004-03-17
US6146825A (en) 2000-11-14
KR100392215B1 (ko) 2003-11-20
DE69519378T2 (de) 2001-07-19
DE69519378D1 (de) 2000-12-14
WO1996001103A1 (en) 1996-01-18
US6150086A (en) 2000-11-21
KR970703755A (ko) 1997-08-09
EP0768870A1 (en) 1997-04-23
JPH10502621A (ja) 1998-03-10

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