DK0766555T3 - Stabiliserede nanopartikler, som kan filtreres under sterile betingelser - Google Patents

Stabiliserede nanopartikler, som kan filtreres under sterile betingelser

Info

Publication number
DK0766555T3
DK0766555T3 DK95923414T DK95923414T DK0766555T3 DK 0766555 T3 DK0766555 T3 DK 0766555T3 DK 95923414 T DK95923414 T DK 95923414T DK 95923414 T DK95923414 T DK 95923414T DK 0766555 T3 DK0766555 T3 DK 0766555T3
Authority
DK
Denmark
Prior art keywords
sterile conditions
under sterile
filtered under
stabilized nanoparticles
water
Prior art date
Application number
DK95923414T
Other languages
Danish (da)
English (en)
Inventor
Michel Laborie
Joel Vacus
Thierry Verrecchia
Marie-Christine Bissery
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0766555T3 publication Critical patent/DK0766555T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/788Of specified organic or carbon-based composition
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/788Of specified organic or carbon-based composition
    • Y10S977/795Composed of biological material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Filtering Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Materials For Medical Uses (AREA)
DK95923414T 1994-06-22 1995-06-20 Stabiliserede nanopartikler, som kan filtreres under sterile betingelser DK0766555T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9407628A FR2721510B1 (fr) 1994-06-22 1994-06-22 Nanoparticules filtrables dans des conditions stériles.
PCT/FR1995/000813 WO1995035101A1 (fr) 1994-06-22 1995-06-20 Nanoparticules stabilisees et filtrables dans des conditions steriles

Publications (1)

Publication Number Publication Date
DK0766555T3 true DK0766555T3 (da) 1999-08-23

Family

ID=9464490

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95923414T DK0766555T3 (da) 1994-06-22 1995-06-20 Stabiliserede nanopartikler, som kan filtreres under sterile betingelser

Country Status (21)

Country Link
US (1) US6146663A (fi)
EP (1) EP0766555B1 (fi)
JP (1) JP3806937B2 (fi)
CN (1) CN1151114A (fi)
AT (1) ATE174791T1 (fi)
AU (1) AU2797995A (fi)
BR (1) BR9508363A (fi)
CA (1) CA2192712A1 (fi)
CZ (1) CZ377296A3 (fi)
DE (1) DE69506867T2 (fi)
DK (1) DK0766555T3 (fi)
ES (1) ES2126905T3 (fi)
FI (1) FI965165A (fi)
FR (1) FR2721510B1 (fi)
HU (1) HUT76549A (fi)
MX (1) MX9606490A (fi)
NO (1) NO965458L (fi)
PL (1) PL317893A1 (fi)
SK (1) SK166696A3 (fi)
WO (1) WO1995035101A1 (fi)
ZA (1) ZA955047B (fi)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8137684B2 (en) * 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
KR101180181B1 (ko) * 1997-06-27 2012-09-05 아브락시스 바이오사이언스, 엘엘씨 나노 입자 및 그의 제조 방법
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
EP1267946A4 (en) 2000-02-28 2008-07-02 Genesegues Inc SYSTEM AND METHOD FOR ENCAPSULATING NANOCAPSULES
CA2309575A1 (en) * 2000-05-26 2001-11-26 James E. Guillet Internally cross-linked macromolecules
US6869617B2 (en) * 2000-12-22 2005-03-22 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US6635173B2 (en) * 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
ES2178961B1 (es) * 2001-03-06 2004-07-01 Instituto Cientifico Y Tecnologico De Navarra, S.A. Fabricacion de nanoparticulas a base del copolimero de metil vinil eter y anhidrido maleico para la administracion de farmacos de naturaleza hidrofilica, en particular de bases puricas y pirimidinicas.
WO2003000226A2 (en) * 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
MXPA04002446A (es) 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7112340B2 (en) * 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
US6960378B1 (en) 2002-06-27 2005-11-01 Rensselaer Polytechnic Institute Tubular microstructures via controlled nanoparticle assembly
ES2665464T3 (es) * 2003-03-28 2018-04-25 Sigmoid Pharma Limited Forma de dosificación oral sólida que contiene microcápsulas sin costuras
US20050196416A1 (en) * 2004-02-05 2005-09-08 Kipp James E. Dispersions prepared by use of self-stabilizing agents
EP2444071A1 (en) * 2004-09-27 2012-04-25 Sigmoid Pharma Limited Minicapsule formulations
US7901711B1 (en) * 2006-04-17 2011-03-08 Gp Medical, Inc. Nanoparticles for protein/peptide delivery and delivery means thereof
US20110177306A1 (en) * 2004-12-17 2011-07-21 Mitsubishi Chemical Corporation Novel Core-Shell Structure
GB0501833D0 (en) * 2005-01-28 2005-03-09 Unilever Plc Carrier liquids and methods of production thereof
KR20090045205A (ko) * 2006-06-26 2009-05-07 뮤추얼 파마슈티컬 컴퍼니 아이엔씨. 활성제 제형 및 이의 제조방법 및 사용방법
WO2008040799A2 (en) * 2006-10-06 2008-04-10 Boehringer Ingelheim International Gmbh Process for preparing instant forms of aqueous mixed micellar solutions as physiological buffer systems for use in the analysis of in vitro release
US20100068251A1 (en) * 2006-10-10 2010-03-18 Jina Pharmaceuticals, Inc. Aqueous Systems For The Preparation Of Lipid Based Pharmaceutical Compounds; Compositions, Methods, And Uses Thereof
EP2066309B1 (en) * 2007-04-04 2012-08-29 Sigmoid Pharma Limited An oral pharmaceutical composition
EP2061587A1 (en) * 2007-04-26 2009-05-27 Sigmoid Pharma Limited Manufacture of multiple minicapsules
CA2685593A1 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Combination pharmaceutical compositions
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
WO2009038591A1 (en) * 2007-09-17 2009-03-26 Yale University Bile salt colloids and methods of making and using thereof
US9233078B2 (en) 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
EP2231169B1 (en) 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US20100159010A1 (en) * 2008-12-24 2010-06-24 Mutual Pharmaceutical Company, Inc. Active Agent Formulations, Methods of Making, and Methods of Use
CA2762179A1 (en) 2009-05-18 2010-11-25 Sigmoid Pharma Limited Composition comprising oil drops
CN107582526A (zh) 2009-08-12 2018-01-16 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
KR20170054429A (ko) 2014-09-03 2017-05-17 제네세규스 인코포레이티드 치료용 나노입자 및 관련 조성물, 방법, 및 시스템
AU2015341695B2 (en) 2014-11-07 2021-07-08 Sublimity Therapeutics Limited Compositions comprising cyclosporin
US10864170B2 (en) 2015-09-04 2020-12-15 Yale University Polymeric bile acid nanocompositions targeting the pancreas and colon

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
US4711895A (en) * 1984-10-22 1987-12-08 Teijin Limited 4-hydroxy-2-cyclopentenone, process for production thereof, pharmaceutical composition comprising it
US5025004A (en) * 1988-06-13 1991-06-18 Eastman Kodak Company Water-dispersible polymeric compositions
SE464743B (sv) * 1989-06-21 1991-06-10 Ytkemiska Inst Foerfarande foer framstaellning av laekemedelspartiklar
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
JP2523926B2 (ja) * 1990-04-04 1996-08-14 松下電器産業株式会社 複合電話機
FR2660556B1 (fr) * 1990-04-06 1994-09-16 Rhone Poulenc Sante Microspheres, leur procede de preparation et leur utilisation.
FR2678168B1 (fr) * 1991-06-28 1993-09-03 Rhone Poulenc Rorer Sa Nanoparticules ayant un temps de capture par le dysteme reticulo endothelial allonge.
FR2678178A1 (fr) * 1991-06-28 1992-12-31 Rhone Poulenc Rorer Sa Procede de preparation de nanoparticules.
GB9300875D0 (en) * 1993-01-18 1993-03-10 Ucb Sa Nanocapsule containing pharmaceutical compositions

Also Published As

Publication number Publication date
CN1151114A (zh) 1997-06-04
FR2721510A1 (fr) 1995-12-29
ATE174791T1 (de) 1999-01-15
CA2192712A1 (fr) 1995-12-28
DE69506867T2 (de) 1999-06-24
HU9603533D0 (en) 1997-02-28
ES2126905T3 (es) 1999-04-01
SK166696A3 (en) 1997-08-06
MX9606490A (es) 1997-03-29
HUT76549A (en) 1997-09-29
NO965458D0 (no) 1996-12-18
JP3806937B2 (ja) 2006-08-09
PL317893A1 (en) 1997-04-28
BR9508363A (pt) 1997-11-04
WO1995035101A1 (fr) 1995-12-28
FI965165A0 (fi) 1996-12-20
EP0766555A1 (fr) 1997-04-09
US6146663A (en) 2000-11-14
DE69506867D1 (de) 1999-02-04
CZ377296A3 (en) 1997-04-16
AU2797995A (en) 1996-01-15
NO965458L (no) 1996-12-18
JPH10501804A (ja) 1998-02-17
EP0766555B1 (fr) 1998-12-23
FI965165A (fi) 1996-12-20
ZA955047B (en) 1996-02-09
FR2721510B1 (fr) 1996-07-26

Similar Documents

Publication Publication Date Title
DK0766555T3 (da) Stabiliserede nanopartikler, som kan filtreres under sterile betingelser
DK0869776T3 (da) Stabiliserede nanopartikler, som kan filtreres under sterile betingelser
BR0110505A (pt) Sistemas de lentes oftálmicas
DE69534762D1 (de) Stabile wasser-in-öl emulsionssysteme
BR9809966B8 (pt) método para embalar e armazenar lentes de contato de hidrogel e sistema para armazenar e fornecer lentes de contato
BR0001817A (pt) Composição em forma de emulsão óleo - em - água, utilização cosmética da composição, processo de tratamento cosmético, utilização da composição e utilização da associação de um organopolissiloxano sólido elastomérico reticulado e de um polìmero hidrossolúvel ou inchável na água
FI852374A0 (fi) Biosoenderfallande amfipatiska copolymerer.
BR0014203A (pt) Formulações de suspensão tópicas contendo ciprofloxacina e dexametasona
ATE375174T1 (de) Zusammensetzung und verfahren zur pflege von kontaktlinsen
MA23219A1 (fr) Emulsions aqueuses stables de tensio-actifs non ioniques
ES2125322T3 (es) Emulsiones acuosas estables de tensioactivos no ionicos con un agente de control de la viscosidad.
PT1157688E (pt) Formulacoes oftalmicas aquosas antibacterianas contendo ofloxacina e quitosano
EP1219349A3 (de) Verwendung teilchenförmiger Polymerisate als Filterhilfsmittel für wässrige Flüssigkeiten
BR9816071A (pt) Emulsão de óleo-em-água contendo um composto de ácido ascórbico
Newell Self-induced abortion and an elevated anion gap
UA31641A (uk) Сополімер n-вінілпірролідону, n,n-диметиламіноетилметакрилату та вінілбутилового ефіру, що проявляє детоксикуючу активність по відношенню до алкілюючих агентів
KR900007438A (ko) 일본뇌염 백신 및 그의 제조방법
TH45863A3 (th) พอลิเมอร์แพร่กระจายที่เป็นสารออกฤทธิ์ชนิดที่สูงกว่าชนิดต่างๆ สำหรับช่วยการทำให้ใส การขจัดน้ำ และการเก็บและการถ่ายล้าง