DK0758648T3 - Substituerede 4H-pyraner med en modulerende virkning på kaliumkanaler - Google Patents
Substituerede 4H-pyraner med en modulerende virkning på kaliumkanalerInfo
- Publication number
- DK0758648T3 DK0758648T3 DK96112427T DK96112427T DK0758648T3 DK 0758648 T3 DK0758648 T3 DK 0758648T3 DK 96112427 T DK96112427 T DK 96112427T DK 96112427 T DK96112427 T DK 96112427T DK 0758648 T3 DK0758648 T3 DK 0758648T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- pyran
- pyrans
- substituted
- potassium channels
- Prior art date
Links
- 150000000531 4H-pyrans Chemical class 0.000 title 1
- 102000004257 Potassium Channel Human genes 0.000 title 1
- 230000003804 effect on potassium Effects 0.000 title 1
- 108020001213 potassium channel Proteins 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- BUTMHFPJIIMPHS-UHFFFAOYSA-N diethyl 2,6-dimethyl-4-phenyl-4h-pyran-3,5-dicarboxylate Chemical compound CCOC(=O)C1=C(C)OC(C)=C(C(=O)OCC)C1C1=CC=CC=C1 BUTMHFPJIIMPHS-UHFFFAOYSA-N 0.000 abstract 2
- JTWVCLIOEDIZSC-UHFFFAOYSA-N 1-(5-acetyl-2,4,6-trimethyl-4h-pyran-3-yl)ethanone Chemical compound CC1C(C(C)=O)=C(C)OC(C)=C1C(C)=O JTWVCLIOEDIZSC-UHFFFAOYSA-N 0.000 abstract 1
- MRUWJENAYHTDQG-UHFFFAOYSA-N 4H-pyran Chemical compound C1C=COC=C1 MRUWJENAYHTDQG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- GWEFWGCEPTVYCU-UHFFFAOYSA-N diethyl 2,4,6-trimethyl-4h-pyran-3,5-dicarboxylate Chemical compound CCOC(=O)C1=C(C)OC(C)=C(C(=O)OCC)C1C GWEFWGCEPTVYCU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19529858A DE19529858A1 (de) | 1995-08-14 | 1995-08-14 | Substituierte 4H-Pyrane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0758648T3 true DK0758648T3 (da) | 2000-07-24 |
Family
ID=7769442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96112427T DK0758648T3 (da) | 1995-08-14 | 1996-08-01 | Substituerede 4H-pyraner med en modulerende virkning på kaliumkanaler |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5760073A (cs) |
| EP (1) | EP0758648B1 (cs) |
| JP (1) | JPH0959271A (cs) |
| KR (1) | KR970010758A (cs) |
| CN (1) | CN1147512A (cs) |
| AT (1) | ATE190611T1 (cs) |
| AU (1) | AU708956B2 (cs) |
| CA (1) | CA2183048A1 (cs) |
| CZ (1) | CZ239496A3 (cs) |
| DE (2) | DE19529858A1 (cs) |
| DK (1) | DK0758648T3 (cs) |
| EE (1) | EE9600114A (cs) |
| ES (1) | ES2145355T3 (cs) |
| GR (1) | GR3033357T3 (cs) |
| HU (1) | HUP9602220A3 (cs) |
| IL (1) | IL119054A (cs) |
| MX (1) | MX9603342A (cs) |
| NO (1) | NO963374L (cs) |
| NZ (1) | NZ299145A (cs) |
| PL (1) | PL315652A1 (cs) |
| PT (1) | PT758648E (cs) |
| RU (1) | RU2164915C2 (cs) |
| SI (1) | SI0758648T1 (cs) |
| SK (1) | SK105596A3 (cs) |
| ZA (1) | ZA966832B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998045263A1 (en) * | 1997-04-07 | 1998-10-15 | Georgetown University | Analogs of cocaine |
| US6221550B1 (en) | 2000-03-31 | 2001-04-24 | Nexpress Solutions Llc | 4H-pyran charge control agents for electrostatographic toners and developers |
| US20090012103A1 (en) * | 2007-07-05 | 2009-01-08 | Matthew Abelman | Substituted heterocyclic compounds |
| WO2009006580A1 (en) * | 2007-07-05 | 2009-01-08 | Cv Therapeutics, Inc. | Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers |
| JP5120070B2 (ja) * | 2008-05-29 | 2013-01-16 | 三浦工業株式会社 | 水処理装置 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2235406C3 (de) * | 1972-07-19 | 1982-01-07 | Bayer Ag, 5090 Leverkusen | 2-Amino-4H-pyrane, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
-
1995
- 1995-08-14 DE DE19529858A patent/DE19529858A1/de not_active Withdrawn
-
1996
- 1996-08-01 AT AT96112427T patent/ATE190611T1/de not_active IP Right Cessation
- 1996-08-01 EP EP96112427A patent/EP0758648B1/de not_active Expired - Lifetime
- 1996-08-01 DK DK96112427T patent/DK0758648T3/da active
- 1996-08-01 DE DE59604649T patent/DE59604649D1/de not_active Expired - Fee Related
- 1996-08-01 PT PT96112427T patent/PT758648E/pt unknown
- 1996-08-01 SI SI9630155T patent/SI0758648T1/xx unknown
- 1996-08-01 ES ES96112427T patent/ES2145355T3/es not_active Expired - Lifetime
- 1996-08-07 US US08/692,964 patent/US5760073A/en not_active Expired - Fee Related
- 1996-08-07 AU AU61931/96A patent/AU708956B2/en not_active Ceased
- 1996-08-09 NZ NZ299145A patent/NZ299145A/en unknown
- 1996-08-09 CA CA002183048A patent/CA2183048A1/en not_active Abandoned
- 1996-08-12 PL PL96315652A patent/PL315652A1/xx unknown
- 1996-08-12 JP JP8227366A patent/JPH0959271A/ja active Pending
- 1996-08-12 CN CN96111368A patent/CN1147512A/zh active Pending
- 1996-08-12 IL IL11905496A patent/IL119054A/xx not_active IP Right Cessation
- 1996-08-13 CZ CZ962394A patent/CZ239496A3/cs unknown
- 1996-08-13 EE EE9600114A patent/EE9600114A/xx unknown
- 1996-08-13 MX MX9603342A patent/MX9603342A/es unknown
- 1996-08-13 NO NO963374A patent/NO963374L/no not_active Application Discontinuation
- 1996-08-13 HU HU9602220A patent/HUP9602220A3/hu unknown
- 1996-08-13 SK SK1055-96A patent/SK105596A3/sk unknown
- 1996-08-13 KR KR1019960033535A patent/KR970010758A/ko not_active Withdrawn
- 1996-08-13 ZA ZA9606832A patent/ZA966832B/xx unknown
- 1996-08-14 RU RU96115463/04A patent/RU2164915C2/ru active
-
2000
- 2000-05-05 GR GR20000401042T patent/GR3033357T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6193196A (en) | 1997-02-20 |
| SI0758648T1 (en) | 2000-06-30 |
| IL119054A0 (en) | 1996-11-14 |
| ES2145355T3 (es) | 2000-07-01 |
| EP0758648A1 (de) | 1997-02-19 |
| IL119054A (en) | 2000-10-31 |
| KR970010758A (ko) | 1997-03-27 |
| ATE190611T1 (de) | 2000-04-15 |
| HUP9602220A2 (en) | 1997-05-28 |
| MX9603342A (es) | 1997-03-29 |
| CZ239496A3 (en) | 1997-03-12 |
| DE59604649D1 (de) | 2000-04-20 |
| PL315652A1 (en) | 1997-02-17 |
| NO963374L (no) | 1997-02-17 |
| PT758648E (pt) | 2000-08-31 |
| NZ299145A (en) | 1998-03-25 |
| AU708956B2 (en) | 1999-08-19 |
| EP0758648B1 (de) | 2000-03-15 |
| JPH0959271A (ja) | 1997-03-04 |
| HUP9602220A3 (en) | 1998-04-28 |
| US5760073A (en) | 1998-06-02 |
| CN1147512A (zh) | 1997-04-16 |
| NO963374D0 (no) | 1996-08-13 |
| HU9602220D0 (en) | 1996-10-28 |
| DE19529858A1 (de) | 1997-02-20 |
| EE9600114A (et) | 1997-02-17 |
| GR3033357T3 (en) | 2000-09-29 |
| RU2164915C2 (ru) | 2001-04-10 |
| CA2183048A1 (en) | 1997-02-15 |
| SK105596A3 (en) | 1997-03-05 |
| ZA966832B (en) | 1997-02-20 |
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