DK0750610T3 - Piperidyl-4-substituerede tyrosinderivater som scintigrafiske billedfrembringende midler til diagnose af thrombose - Google Patents
Piperidyl-4-substituerede tyrosinderivater som scintigrafiske billedfrembringende midler til diagnose af thromboseInfo
- Publication number
- DK0750610T3 DK0750610T3 DK95914746T DK95914746T DK0750610T3 DK 0750610 T3 DK0750610 T3 DK 0750610T3 DK 95914746 T DK95914746 T DK 95914746T DK 95914746 T DK95914746 T DK 95914746T DK 0750610 T3 DK0750610 T3 DK 0750610T3
- Authority
- DK
- Denmark
- Prior art keywords
- imaging agents
- scintigraphic imaging
- piperidyl
- thrombosis
- diagnosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21082294A | 1994-03-18 | 1994-03-18 | |
PCT/US1995/003366 WO1995025720A1 (fr) | 1994-03-18 | 1995-03-17 | Derives de thyrosine a substitution piperidyle en position 4 utilises comme agents de representation scintigraphique pour le diagnostique de la thrombose |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0750610T3 true DK0750610T3 (da) | 2002-03-11 |
Family
ID=22784384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95914746T DK0750610T3 (da) | 1994-03-18 | 1995-03-17 | Piperidyl-4-substituerede tyrosinderivater som scintigrafiske billedfrembringende midler til diagnose af thrombose |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0750610B1 (fr) |
AT (1) | ATE210644T1 (fr) |
AU (1) | AU2186695A (fr) |
DE (1) | DE69524580T2 (fr) |
DK (1) | DK0750610T3 (fr) |
ES (1) | ES2169756T3 (fr) |
WO (1) | WO1995025720A1 (fr) |
ZA (1) | ZA952206B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2141102T3 (es) * | 1991-02-08 | 2000-03-16 | Diatide Inc | Polipeptidos marcados con tecnecio-99m para la generacion de imagenes. |
US5645815A (en) | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
US5736122A (en) * | 1991-02-08 | 1998-04-07 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US5951981A (en) * | 1996-12-02 | 1999-09-14 | Diatide, Inc. | Thrombolytic agents with antithrombotic activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204350A (en) * | 1991-08-09 | 1993-04-20 | Merck & Co., Inc. | Method of inhibiting osteoclast-mediated bone resorption by administration of n-heterocyclicalkyl-substituted phenyl derivatives |
US5508020A (en) * | 1992-06-05 | 1996-04-16 | Diatech, Inc. | Technetium-99M labeled peptides for imaging |
DK0641222T3 (da) * | 1992-05-21 | 2000-12-11 | Diatide Inc | Peptider mærket med technetium-99m til trombeafbildning |
-
1995
- 1995-03-17 AU AU21866/95A patent/AU2186695A/en not_active Abandoned
- 1995-03-17 DE DE69524580T patent/DE69524580T2/de not_active Expired - Fee Related
- 1995-03-17 EP EP95914746A patent/EP0750610B1/fr not_active Expired - Lifetime
- 1995-03-17 WO PCT/US1995/003366 patent/WO1995025720A1/fr active IP Right Grant
- 1995-03-17 AT AT95914746T patent/ATE210644T1/de not_active IP Right Cessation
- 1995-03-17 ES ES95914746T patent/ES2169756T3/es not_active Expired - Lifetime
- 1995-03-17 ZA ZA952206A patent/ZA952206B/xx unknown
- 1995-03-17 DK DK95914746T patent/DK0750610T3/da active
Also Published As
Publication number | Publication date |
---|---|
WO1995025720A1 (fr) | 1995-09-28 |
DE69524580T2 (de) | 2002-07-25 |
EP0750610B1 (fr) | 2001-12-12 |
AU2186695A (en) | 1995-10-09 |
ATE210644T1 (de) | 2001-12-15 |
ES2169756T3 (es) | 2002-07-16 |
EP0750610A1 (fr) | 1997-01-02 |
DE69524580D1 (de) | 2002-01-24 |
ZA952206B (en) | 1995-12-12 |
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