ATE258176T1 - Neue azabicyclo derivate und ihre verwendung - Google Patents

Neue azabicyclo derivate und ihre verwendung

Info

Publication number
ATE258176T1
ATE258176T1 AT00901487T AT00901487T ATE258176T1 AT E258176 T1 ATE258176 T1 AT E258176T1 AT 00901487 T AT00901487 T AT 00901487T AT 00901487 T AT00901487 T AT 00901487T AT E258176 T1 ATE258176 T1 AT E258176T1
Authority
AT
Austria
Prior art keywords
derivatives
azabicyclo derivatives
new
new azabicyclo
labelled
Prior art date
Application number
AT00901487T
Other languages
English (en)
Inventor
Dan Peters
Joergen Scheel-Krueger
Elsebet Oestergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE258176T1 publication Critical patent/ATE258176T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00901487T 1999-01-28 2000-01-28 Neue azabicyclo derivate und ihre verwendung ATE258176T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199900106 1999-01-28
DKPA199900950 1999-07-01
PCT/DK2000/000038 WO2000044746A1 (en) 1999-01-28 2000-01-28 Novel azabicyclo derivatives and their use

Publications (1)

Publication Number Publication Date
ATE258176T1 true ATE258176T1 (de) 2004-02-15

Family

ID=26063317

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00901487T ATE258176T1 (de) 1999-01-28 2000-01-28 Neue azabicyclo derivate und ihre verwendung

Country Status (6)

Country Link
US (1) US6617459B2 (de)
EP (1) EP1149095B1 (de)
AT (1) ATE258176T1 (de)
AU (1) AU2278700A (de)
DE (1) DE60007841T2 (de)
WO (1) WO2000044746A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2269467T3 (es) 2000-10-13 2007-04-01 Neurosearch A/S Tratamiento de transtornos afectivos por la accion combinada de un agonista del receptor nicotinico y una sustancia monoaminergenica.
US20070218002A1 (en) * 2004-05-07 2007-09-20 Barrio Jorge R Method for Detecting Alzheimer's Disease and other Forms of Dementia, and Measuring Their Progression
AU2005276624B2 (en) 2004-08-25 2011-09-29 Actelion Pharmaceuticals Ltd. Bicyclononene derivatives as renin inhibitors
JP2008524305A (ja) * 2004-12-22 2008-07-10 ノイロサーチ アクティーゼルスカブ 新規なナフチル置換アザビシクロ誘導体、及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用
MX2007012472A (es) * 2005-04-08 2007-12-06 Neurosearch As (+)-y-(-)-8-alquil-3-(trifluoralquilsulfoniloxi)-8-azabicicl (3.2.1)cot-2-eno.
WO2006117218A2 (en) * 2005-05-04 2006-11-09 Charite Universitätsmedizin - Berlin Serotonin-transport-protein binding radiopharmaceutical for the production of a diagnostic medicament for the diagnosis of headache
EP1728520A1 (de) * 2005-05-04 2006-12-06 Charité - Universitätsmedizin Berlin Verwendung von spezifisch an das Serotonin-Transport-Protein (SERT) bindenden Radiopharmaka zur Herstellung eines Diagnostikums zur Untersuchung von Kopfschmerzerkrankungen
US8114382B2 (en) * 2006-12-11 2012-02-14 General Electric Company Myelin detection using benzofuran derivatives
US8509884B2 (en) * 2009-08-28 2013-08-13 Neba Health LLC Systems and methods to identify a subgroup of ADHD at higher risk for complicating conditions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3509161A (en) * 1967-07-10 1970-04-28 Boehringer & Soehne Gmbh 3-phenyl-granatene-(2)-derivatives
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
EP0859777B1 (de) * 1995-10-13 2007-05-23 Neurosearch A/S 8-azabicyclo(3.2.1)oct-2en-derivate, deren herstellung und anwendung
GB9706222D0 (en) * 1997-03-26 1997-05-14 Zeneca Ltd Bicyclic amine derivatives
CN1205210C (zh) * 1997-05-30 2005-06-08 神经研究公司 作为尼古丁ACh受体上胆碱能配体的9－氮杂双环(3.3.1)壬－2－烯衍生物
IL132437A0 (en) * 1997-05-30 2001-03-19 Neurosearch As 8-Azabicyclo(3,2,1)oct-2-ene and octane derivatives as cholinergic ligands at nicotinic ach receptors
AU2609999A (en) * 1998-01-28 1999-08-16 Neurosearch A/S 8-azabicyclo(3.2.1)oct-2-ene derivatives in labelled and use of 8-azabicyclo(3.2.1)oct-2-ene derivatives in labelled and unlabelled form

Also Published As

Publication number Publication date
US6617459B2 (en) 2003-09-09
US20010047028A1 (en) 2001-11-29
DE60007841D1 (de) 2004-02-26
AU2278700A (en) 2000-08-18
EP1149095A1 (de) 2001-10-31
WO2000044746A1 (en) 2000-08-03
EP1149095B1 (de) 2004-01-21
DE60007841T2 (de) 2004-07-08

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties