DK0743301T3 - Fluorholdige benzoylguanidiner - Google Patents
Fluorholdige benzoylguanidinerInfo
- Publication number
- DK0743301T3 DK0743301T3 DK96106881T DK96106881T DK0743301T3 DK 0743301 T3 DK0743301 T3 DK 0743301T3 DK 96106881 T DK96106881 T DK 96106881T DK 96106881 T DK96106881 T DK 96106881T DK 0743301 T3 DK0743301 T3 DK 0743301T3
- Authority
- DK
- Denmark
- Prior art keywords
- cnfmh2n
- mop
- opt
- het
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19517848A DE19517848A1 (de) | 1995-05-16 | 1995-05-16 | Fluorhaltige Benzoylguanidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0743301T3 true DK0743301T3 (da) | 2001-11-26 |
Family
ID=7761987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96106881T DK0743301T3 (da) | 1995-05-16 | 1996-05-02 | Fluorholdige benzoylguanidiner |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5747539A (ru) |
| EP (1) | EP0743301B1 (ru) |
| JP (1) | JPH08311011A (ru) |
| KR (1) | KR960041154A (ru) |
| CN (1) | CN1064955C (ru) |
| AT (1) | ATE204856T1 (ru) |
| AU (1) | AU713743B2 (ru) |
| CA (1) | CA2176553A1 (ru) |
| CZ (1) | CZ287750B6 (ru) |
| DE (2) | DE19517848A1 (ru) |
| DK (1) | DK0743301T3 (ru) |
| ES (1) | ES2161936T3 (ru) |
| GR (1) | GR3037033T3 (ru) |
| HU (1) | HU223046B1 (ru) |
| NO (1) | NO306157B1 (ru) |
| PL (1) | PL184192B1 (ru) |
| PT (1) | PT743301E (ru) |
| RU (1) | RU2159230C2 (ru) |
| SI (1) | SI0743301T1 (ru) |
| SK (1) | SK282052B6 (ru) |
| TW (1) | TW363052B (ru) |
| UA (1) | UA44260C2 (ru) |
| ZA (1) | ZA963870B (ru) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4328352A1 (de) * | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19606509A1 (de) * | 1996-02-22 | 1997-08-28 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19608161A1 (de) | 1996-03-04 | 1997-09-11 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US5747639A (en) * | 1996-03-06 | 1998-05-05 | Amgen Boulder Inc. | Use of hydrophobic interaction chromatography to purify polyethylene glycols |
| DE19713427A1 (de) * | 1997-04-01 | 1998-10-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| CZ20011785A3 (cs) * | 1998-11-26 | 2001-10-17 | Merck Patent Gmbh | Pouľití benzoylguanidinů pro oąetřování diabetes mellitus nezávislého na inzulínu |
| US7375138B2 (en) * | 2002-05-18 | 2008-05-20 | Sanofi-Aventis Deutschland Gmbh | Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them |
| DE10222192A1 (de) * | 2002-05-18 | 2003-11-27 | Aventis Pharma Gmbh | Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| OA13285A (en) * | 2003-11-13 | 2007-01-31 | Sanofi Aventis Deutschland | Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same. |
| US20050124666A1 (en) * | 2003-11-13 | 2005-06-09 | Aventis Pharma Deutschland Gmbh | Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same |
| DE10353204A1 (de) * | 2003-11-13 | 2005-06-16 | Aventis Pharma Deutschland Gmbh | Verfahren zur Herstellung von 4-Pentafluorsulfanyl-benzoylguanidinen |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
| ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
| DE59307360D1 (de) * | 1992-02-15 | 1997-10-23 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| ES2097409T3 (es) * | 1992-09-22 | 1997-04-01 | Hoechst Ag | Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos. |
| TW250479B (ru) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| TW250477B (ru) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
| DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4417004A1 (de) * | 1994-05-13 | 1995-11-16 | Hoechst Ag | Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4430916A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Alkyl-benzoylguanidin-Derivate |
-
1995
- 1995-05-16 DE DE19517848A patent/DE19517848A1/de not_active Withdrawn
-
1996
- 1996-03-25 TW TW085103561A patent/TW363052B/zh active
- 1996-05-02 SI SI9630361T patent/SI0743301T1/xx unknown
- 1996-05-02 DE DE59607559T patent/DE59607559D1/de not_active Expired - Fee Related
- 1996-05-02 DK DK96106881T patent/DK0743301T3/da active
- 1996-05-02 AT AT96106881T patent/ATE204856T1/de not_active IP Right Cessation
- 1996-05-02 PT PT96106881T patent/PT743301E/pt unknown
- 1996-05-02 EP EP96106881A patent/EP0743301B1/de not_active Expired - Lifetime
- 1996-05-02 ES ES96106881T patent/ES2161936T3/es not_active Expired - Lifetime
- 1996-05-09 SK SK590-96A patent/SK282052B6/sk unknown
- 1996-05-13 AU AU52252/96A patent/AU713743B2/en not_active Ceased
- 1996-05-13 UA UA96051860A patent/UA44260C2/uk unknown
- 1996-05-13 CN CN961058854A patent/CN1064955C/zh not_active Expired - Fee Related
- 1996-05-14 CA CA002176553A patent/CA2176553A1/en not_active Abandoned
- 1996-05-15 HU HU9601305A patent/HU223046B1/hu not_active IP Right Cessation
- 1996-05-15 RU RU96109204/04A patent/RU2159230C2/ru not_active IP Right Cessation
- 1996-05-15 US US08/647,789 patent/US5747539A/en not_active Expired - Fee Related
- 1996-05-15 PL PL96314259A patent/PL184192B1/pl unknown
- 1996-05-15 NO NO961997A patent/NO306157B1/no not_active IP Right Cessation
- 1996-05-15 KR KR1019960016096A patent/KR960041154A/ko active IP Right Grant
- 1996-05-15 ZA ZA963870A patent/ZA963870B/xx unknown
- 1996-05-15 CZ CZ19961408A patent/CZ287750B6/cs not_active IP Right Cessation
- 1996-05-16 JP JP8144881A patent/JPH08311011A/ja active Pending
-
2001
- 2001-10-30 GR GR20010401903T patent/GR3037033T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA963870B (en) | 1996-11-21 |
| EP0743301A2 (de) | 1996-11-20 |
| EP0743301B1 (de) | 2001-08-29 |
| NO306157B1 (no) | 1999-09-27 |
| ATE204856T1 (de) | 2001-09-15 |
| CA2176553A1 (en) | 1996-11-17 |
| HU9601305D0 (en) | 1996-07-29 |
| RU2159230C2 (ru) | 2000-11-20 |
| EP0743301A3 (de) | 1997-06-11 |
| UA44260C2 (uk) | 2002-02-15 |
| AU5225296A (en) | 1996-11-28 |
| NO961997D0 (no) | 1996-05-15 |
| TW363052B (en) | 1999-07-01 |
| PL184192B1 (pl) | 2002-09-30 |
| US5747539A (en) | 1998-05-05 |
| CZ287750B6 (en) | 2001-01-17 |
| NO961997L (no) | 1996-11-18 |
| DE59607559D1 (de) | 2001-10-04 |
| SI0743301T1 (en) | 2002-02-28 |
| DE19517848A1 (de) | 1996-11-21 |
| SK282052B6 (sk) | 2001-10-08 |
| HUP9601305A3 (en) | 1997-11-28 |
| JPH08311011A (ja) | 1996-11-26 |
| PL314259A1 (en) | 1996-11-25 |
| HUP9601305A2 (en) | 1997-05-28 |
| SK59096A3 (en) | 1996-12-04 |
| KR960041154A (ko) | 1996-12-19 |
| AU713743B2 (en) | 1999-12-09 |
| GR3037033T3 (en) | 2002-01-31 |
| ES2161936T3 (es) | 2001-12-16 |
| CN1143632A (zh) | 1997-02-26 |
| PT743301E (pt) | 2002-01-30 |
| CZ140896A3 (en) | 1997-02-12 |
| HU223046B1 (hu) | 2004-03-01 |
| CN1064955C (zh) | 2001-04-25 |
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