NO961997L - Fluorholdige benzoylguanidiner - Google Patents

Fluorholdige benzoylguanidiner

Info

Publication number
NO961997L
NO961997L NO961997A NO961997A NO961997L NO 961997 L NO961997 L NO 961997L NO 961997 A NO961997 A NO 961997A NO 961997 A NO961997 A NO 961997A NO 961997 L NO961997 L NO 961997L
Authority
NO
Norway
Prior art keywords
cnfmh2n
mop
opt
het
halo
Prior art date
Application number
NO961997A
Other languages
English (en)
Other versions
NO961997D0 (no
NO306157B1 (no
Inventor
Dieter Dorsch
Manfred Baumgarth
Rolf Gericke
Klaus-Otto Minck
Norbert Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO961997D0 publication Critical patent/NO961997D0/no
Publication of NO961997L publication Critical patent/NO961997L/no
Publication of NO306157B1 publication Critical patent/NO306157B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO961997A 1995-05-16 1996-05-15 Fluorholdige benzoylguanidiner, farmasöytiske preparater som inneholder minst én slik forbindelse, samt anvendelse av forbindelsene til fremstilling av et legemiddel NO306157B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19517848A DE19517848A1 (de) 1995-05-16 1995-05-16 Fluorhaltige Benzoylguanidine

Publications (3)

Publication Number Publication Date
NO961997D0 NO961997D0 (no) 1996-05-15
NO961997L true NO961997L (no) 1996-11-18
NO306157B1 NO306157B1 (no) 1999-09-27

Family

ID=7761987

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961997A NO306157B1 (no) 1995-05-16 1996-05-15 Fluorholdige benzoylguanidiner, farmasöytiske preparater som inneholder minst én slik forbindelse, samt anvendelse av forbindelsene til fremstilling av et legemiddel

Country Status (23)

Country Link
US (1) US5747539A (no)
EP (1) EP0743301B1 (no)
JP (1) JPH08311011A (no)
KR (1) KR960041154A (no)
CN (1) CN1064955C (no)
AT (1) ATE204856T1 (no)
AU (1) AU713743B2 (no)
CA (1) CA2176553A1 (no)
CZ (1) CZ287750B6 (no)
DE (2) DE19517848A1 (no)
DK (1) DK0743301T3 (no)
ES (1) ES2161936T3 (no)
GR (1) GR3037033T3 (no)
HU (1) HU223046B1 (no)
NO (1) NO306157B1 (no)
PL (1) PL184192B1 (no)
PT (1) PT743301E (no)
RU (1) RU2159230C2 (no)
SI (1) SI0743301T1 (no)
SK (1) SK282052B6 (no)
TW (1) TW363052B (no)
UA (1) UA44260C2 (no)
ZA (1) ZA963870B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328352A1 (de) * 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19606509A1 (de) * 1996-02-22 1997-08-28 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19608161A1 (de) 1996-03-04 1997-09-11 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
DE19713427A1 (de) * 1997-04-01 1998-10-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
JP2002530325A (ja) * 1998-11-26 2002-09-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 非インスリン依存型真性糖尿病の治療へのベンゾイルグアニジンの使用
DE10222192A1 (de) * 2002-05-18 2003-11-27 Aventis Pharma Gmbh Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
DE10353204A1 (de) * 2003-11-13 2005-06-16 Aventis Pharma Deutschland Gmbh Verfahren zur Herstellung von 4-Pentafluorsulfanyl-benzoylguanidinen
US20050124666A1 (en) * 2003-11-13 2005-06-09 Aventis Pharma Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE59307360D1 (de) * 1992-02-15 1997-10-23 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0556674B1 (de) * 1992-02-15 1996-06-19 Hoechst Aktiengesellschaft 3,5-Substituierte Benzoylguanidine, mit antiarrythmischer Wirkung und inhibierender Wirkung auf die Proliferationen von Zellen
DK0589336T3 (da) * 1992-09-22 1997-06-16 Hoechst Ag Benzylguanidiner, fremgangsmåde til deres fremstilling samt deres anvendelse som antiarytmetika
TW250477B (no) * 1992-12-15 1995-07-01 Hoechst Ag
TW250479B (no) * 1992-12-15 1995-07-01 Hoechst Ag
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4417004A1 (de) * 1994-05-13 1995-11-16 Hoechst Ag Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4430916A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl-benzoylguanidin-Derivate

Also Published As

Publication number Publication date
NO961997D0 (no) 1996-05-15
SK59096A3 (en) 1996-12-04
DE59607559D1 (de) 2001-10-04
ATE204856T1 (de) 2001-09-15
HUP9601305A2 (en) 1997-05-28
UA44260C2 (uk) 2002-02-15
SI0743301T1 (en) 2002-02-28
ES2161936T3 (es) 2001-12-16
CN1064955C (zh) 2001-04-25
HU9601305D0 (en) 1996-07-29
NO306157B1 (no) 1999-09-27
JPH08311011A (ja) 1996-11-26
CA2176553A1 (en) 1996-11-17
RU2159230C2 (ru) 2000-11-20
CZ287750B6 (en) 2001-01-17
PL314259A1 (en) 1996-11-25
GR3037033T3 (en) 2002-01-31
AU713743B2 (en) 1999-12-09
PT743301E (pt) 2002-01-30
PL184192B1 (pl) 2002-09-30
US5747539A (en) 1998-05-05
EP0743301A2 (de) 1996-11-20
AU5225296A (en) 1996-11-28
SK282052B6 (sk) 2001-10-08
CN1143632A (zh) 1997-02-26
TW363052B (en) 1999-07-01
CZ140896A3 (en) 1997-02-12
HU223046B1 (hu) 2004-03-01
DK0743301T3 (da) 2001-11-26
EP0743301A3 (de) 1997-06-11
HUP9601305A3 (en) 1997-11-28
ZA963870B (en) 1996-11-21
DE19517848A1 (de) 1996-11-21
EP0743301B1 (de) 2001-08-29
KR960041154A (ko) 1996-12-19

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