DK0742214T3 - I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne - Google Patents

I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne

Info

Publication number
DK0742214T3
DK0742214T3 DK96830206T DK96830206T DK0742214T3 DK 0742214 T3 DK0742214 T3 DK 0742214T3 DK 96830206 T DK96830206 T DK 96830206T DK 96830206 T DK96830206 T DK 96830206T DK 0742214 T3 DK0742214 T3 DK 0742214T3
Authority
DK
Denmark
Prior art keywords
new
seco
steroids
well
pharmaceutical preparations
Prior art date
Application number
DK96830206T
Other languages
Danish (da)
English (en)
Inventor
Mauro Gobbini
Patrizia Ferrari
Piero Melloni
Marco Torri
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0742214T3 publication Critical patent/DK0742214T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
DK96830206T 1995-05-11 1996-04-11 I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne DK0742214T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95RM000303A IT1282286B1 (it) 1995-05-11 1995-05-11 Seco-d steroidi sul sistema cardiovascolare, processi per la loro preparazione e composizioni farmaceutiche che li contengono.

Publications (1)

Publication Number Publication Date
DK0742214T3 true DK0742214T3 (da) 1999-12-13

Family

ID=11403363

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96830206T DK0742214T3 (da) 1995-05-11 1996-04-11 I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne

Country Status (10)

Country Link
US (1) US5731345A (de)
EP (1) EP0742214B1 (de)
JP (1) JPH09291086A (de)
AT (1) ATE181324T1 (de)
CA (1) CA2174715A1 (de)
DE (1) DE69602886T2 (de)
DK (1) DK0742214T3 (de)
ES (1) ES2133918T3 (de)
GR (1) GR3031118T3 (de)
IT (1) IT1282286B1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19633376A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue Seco-D-Steroide, die auf das kardiovaskuläre System wirken, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20040064050A1 (en) * 2002-09-20 2004-04-01 Jun Liu System and method for screening tissue
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Ｃｒを含むタンパク質に対して特異的な受容体−結合タンパク質（ｒａｐ）変異体を含む組成物およびその使用
ATE541855T1 (de) * 2005-11-25 2012-02-15 Rostaquo S P A Weitere kristalline formen von rostafuroxin
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4221636C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate
DE4221538C1 (de) * 1992-07-01 1994-03-31 Sigma Tau Ind Farmaceuti 14-Desoxy-14alpha-cardenolid-3beta-thioderivate
DE4227605C2 (de) * 1992-08-20 1995-02-16 Sigma Tau Ind Farmaceuti 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten

Also Published As

Publication number Publication date
ATE181324T1 (de) 1999-07-15
US5731345A (en) 1998-03-24
EP0742214A1 (de) 1996-11-13
GR3031118T3 (en) 1999-12-31
ITRM950303A0 (it) 1995-05-11
JPH09291086A (ja) 1997-11-11
CA2174715A1 (en) 1996-11-12
DE69602886D1 (de) 1999-07-22
EP0742214B1 (de) 1999-06-16
ES2133918T3 (es) 1999-09-16
IT1282286B1 (it) 1998-03-16
DE69602886T2 (de) 1999-11-04
ITRM950303A1 (it) 1996-11-11

Similar Documents

Publication Publication Date Title
AU7576896A (en) Lipopolyamines as transfection agents and their pharmaceutical applications
DE69331774D1 (de) 7-Substituierte-8-substituierte-9-substituierte Amino-7-Demethyl-6-Deoxy-Tetracycline als antibiotische Mittel
ATE205472T1 (de) 9-((substituierte glycyl)amido)-6-demethyl-6- deoxytetracycline als antibiotische mittel
CA2201477A1 (en) New pyrimidone derivatives with antifungal activity
NZ233735A (en) Heterocyclic substituted aminophenol derivatives
FI925734A0 (fi) Polyaspartamidderivat som adsorptionsmedel foer gallsyra, polyaspartamidderivat innehaollande gallsyror och foerfarande foer framstaellning av dessa samt anvaendning av dessa som laekemedel
NO944419D0 (no) Derivater av dolastatin
DK0742214T3 (da) I hjerte-kar-systemet aktive, nye seco-D steroider samt farmaceutiske præparater indeholdende sådanne
DK0692484T3 (da) Benzothiadiazinderivat, fremgangsmåde til fremstilling deraf samt farmaceutiske sammensætninger indeholdende derivatet
DE4493718T1 (de) Abbaubare Succinsäurederivatchelanten, Verwendungen und Zusammensetzungen davon
CA2218663A1 (en) Benzisoxazole and indazole derivatives as antipsychotic agents
DK0719276T3 (da) Ïstradiolestre med stærk oral virkning samt farmaceutiske præparater med indhold deraf
IT1250410B (it) Composti steroidei attivi sul sistema cardiovascolare
FI923751A (fi) Hexahydrobenso/f/kinolinoner
DE69431662D1 (de) Stabilisierte tablettenformulierung
WO1995022544A3 (de) Substituierte 1,3,8-triaza-spiro(4,5)-decan-4-on-derivate als vorstufen zur herstellung von pharmazeutika
MY109202A (en) Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient
DE69614552D1 (de) MODIFIZIERTE ALPHA-D-GLCP-(1,2)-ALPHA-D-Glcp-(1,3)-ALPHA-D-Glcp-ANALOGE
ITMI920076A1 (it) Composti steroidei 17-aril-sostituiti attivi sul sistema cardiovascolare
IT1262931B (it) Composti steroidei 17(piridazin-n-ossido)-sostituiti attivi sul sistema cardiovascolare