DK0728015T3 - Kombinatoriske polypeptidantigener - Google Patents

Kombinatoriske polypeptidantigener

Info

Publication number
DK0728015T3
DK0728015T3 DK93916641T DK93916641T DK0728015T3 DK 0728015 T3 DK0728015 T3 DK 0728015T3 DK 93916641 T DK93916641 T DK 93916641T DK 93916641 T DK93916641 T DK 93916641T DK 0728015 T3 DK0728015 T3 DK 0728015T3
Authority
DK
Denmark
Prior art keywords
polypeptide antigens
variants
combinatorial polypeptide
protein
antigens
Prior art date
Application number
DK93916641T
Other languages
Danish (da)
English (en)
Inventor
Roberto Crea
Original Assignee
Creagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creagen Inc filed Critical Creagen Inc
Application granted granted Critical
Publication of DK0728015T3 publication Critical patent/DK0728015T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK93916641T 1992-06-18 1993-06-18 Kombinatoriske polypeptidantigener DK0728015T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90012392A 1992-06-18 1992-06-18

Publications (1)

Publication Number Publication Date
DK0728015T3 true DK0728015T3 (da) 2006-07-17

Family

ID=25412008

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916641T DK0728015T3 (da) 1992-06-18 1993-06-18 Kombinatoriske polypeptidantigener

Country Status (10)

Country Link
US (1) US6432675B1 (ja)
EP (1) EP0728015B1 (ja)
JP (2) JP3764476B2 (ja)
AT (1) ATE319738T1 (ja)
AU (1) AU678371B2 (ja)
DE (1) DE69333992T2 (ja)
DK (1) DK0728015T3 (ja)
ES (1) ES2260754T3 (ja)
PT (1) PT728015E (ja)
WO (1) WO1994000151A1 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118874B2 (en) 1998-10-09 2006-10-10 Variation Biotechnologies Inc. Immunogenic formulation and process for preparation thereof
WO2003066090A1 (en) * 2002-02-08 2003-08-14 Variation Biotechnologies Inc. Immunogenic formulations of variable peptidic epitopes and process for preparation thereof
NZ535928A (en) * 2002-04-17 2006-09-29 Roberto Crea Determining the ratio of prototype nucleotides to predetermined nucleotides, which is preferably greater than 1:1, by doping in walk-through mutagenesis
RU2237065C2 (ru) * 2002-10-03 2004-09-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Иммуногенная библиотека химерных пептидов, мимикрирующая генетическое многообразие гипервариабельного района v3 белка оболочки gp120 вируса иммунодефицита человека
WO2007030518A2 (en) * 2005-09-06 2007-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Conformationally stabilized hiv envelope immunogens and triggering hiv-1 envelope to reveal cryptic v3-loop epitopes
EP1948227A4 (en) * 2005-10-26 2010-03-31 Protelix Inc COMBINATORY ANTIGEN VACCINE AGAINST FLU
WO2007084568A2 (en) 2006-01-17 2007-07-26 Health Research, Inc. Heteroduplex tracking assay
JP5247009B2 (ja) * 2006-06-16 2013-07-24 独立行政法人理化学研究所 配列抽出装置、配列抽出方法、プログラムおよび記録媒体
WO2009143133A2 (en) * 2008-05-19 2009-11-26 Virginia Tech Intellectual Properties, Inc. Compositions and methods to protect cells by blocking entry of pathogen proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255190A3 (en) 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
EP0311228A3 (en) 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
DE68927933T2 (de) 1988-09-02 1997-08-14 Dyax Corp Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen
AU640619B2 (en) 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
PT94276A (pt) 1989-06-05 1991-02-08 Anticorpo monoclonal capaz de neutralizar o prototipo mn de hiv
WO1991006575A1 (en) 1989-11-03 1991-05-16 Repligen Corporation Hiv-1 specific human monoclonal antibody
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method

Also Published As

Publication number Publication date
JP3764476B2 (ja) 2006-04-05
EP0728015A1 (en) 1996-08-28
EP0728015B1 (en) 2006-03-08
US6432675B1 (en) 2002-08-13
PT728015E (pt) 2006-07-31
AU678371B2 (en) 1997-05-29
WO1994000151A1 (en) 1994-01-06
DE69333992T2 (de) 2006-11-30
JP2004121266A (ja) 2004-04-22
DE69333992D1 (de) 2006-05-04
EP0728015A4 (en) 1997-01-29
AU4642893A (en) 1994-01-24
ES2260754T3 (es) 2006-11-01
JPH07508520A (ja) 1995-09-21
ATE319738T1 (de) 2006-03-15

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