DK0728015T3 - Kombinatoriske polypeptidantigener - Google Patents

Kombinatoriske polypeptidantigener

Info

Publication number
DK0728015T3
DK0728015T3 DK93916641T DK93916641T DK0728015T3 DK 0728015 T3 DK0728015 T3 DK 0728015T3 DK 93916641 T DK93916641 T DK 93916641T DK 93916641 T DK93916641 T DK 93916641T DK 0728015 T3 DK0728015 T3 DK 0728015T3
Authority
DK
Denmark
Prior art keywords
polypeptide antigens
variants
combinatorial polypeptide
protein
antigens
Prior art date
Application number
DK93916641T
Other languages
Danish (da)
English (en)
Inventor
Roberto Crea
Original Assignee
Creagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creagen Inc filed Critical Creagen Inc
Application granted granted Critical
Publication of DK0728015T3 publication Critical patent/DK0728015T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93916641T 1992-06-18 1993-06-18 Kombinatoriske polypeptidantigener DK0728015T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90012392A 1992-06-18 1992-06-18

Publications (1)

Publication Number Publication Date
DK0728015T3 true DK0728015T3 (da) 2006-07-17

Family

ID=25412008

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916641T DK0728015T3 (da) 1992-06-18 1993-06-18 Kombinatoriske polypeptidantigener

Country Status (10)

Country Link
US (1) US6432675B1 (fr)
EP (1) EP0728015B1 (fr)
JP (2) JP3764476B2 (fr)
AT (1) ATE319738T1 (fr)
AU (1) AU678371B2 (fr)
DE (1) DE69333992T2 (fr)
DK (1) DK0728015T3 (fr)
ES (1) ES2260754T3 (fr)
PT (1) PT728015E (fr)
WO (1) WO1994000151A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7118874B2 (en) 1998-10-09 2006-10-10 Variation Biotechnologies Inc. Immunogenic formulation and process for preparation thereof
JP4391827B2 (ja) * 2002-02-08 2009-12-24 バリエーション バイオテクノロジーズ インコーポレイティド 可変性ペプチドエピトープの免疫原性製剤及びその製造方法
DE60316547T2 (de) * 2002-04-17 2008-07-03 Bioren, Inc., San Carlos Doping bei der walk-through-mutagenese
RU2237065C2 (ru) * 2002-10-03 2004-09-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Иммуногенная библиотека химерных пептидов, мимикрирующая генетическое многообразие гипервариабельного района v3 белка оболочки gp120 вируса иммунодефицита человека
US8044185B2 (en) * 2005-09-06 2011-10-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Conformationally stabilized HIV envelope immunogens and triggering HIV-I envelope to reveal cryptic V3-loop epitopes
US20090169576A1 (en) * 2005-10-26 2009-07-02 Roberto Crea Influenza combinatorial antigen vaccine
CA2637600A1 (fr) 2006-01-17 2007-07-26 Health Research, Inc. Bio-essai de suivi en heteroduplex
JP5247009B2 (ja) * 2006-06-16 2013-07-24 独立行政法人理化学研究所 配列抽出装置、配列抽出方法、プログラムおよび記録媒体
US20100093601A1 (en) * 2008-05-19 2010-04-15 Brett Tyler Compositions and methods to protect cells by blocking entry of pathogen proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0525828A3 (en) 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
EP0311228A3 (fr) 1987-10-09 1990-05-02 Repligen Corporation Polypeptides recombinants et leur utilisation, y compris un diagnostic pour le virus du SIDA
US5010175A (en) * 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
AU4308689A (en) 1988-09-02 1990-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
AU640619B2 (en) 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
PT94276A (pt) 1989-06-05 1991-02-08 Anticorpo monoclonal capaz de neutralizar o prototipo mn de hiv
WO1991006575A1 (fr) 1989-11-03 1991-05-16 Repligen Corporation Anticorps monoclonal humain specifique du vih-1
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method

Also Published As

Publication number Publication date
WO1994000151A1 (fr) 1994-01-06
DE69333992T2 (de) 2006-11-30
PT728015E (pt) 2006-07-31
DE69333992D1 (de) 2006-05-04
AU4642893A (en) 1994-01-24
JPH07508520A (ja) 1995-09-21
JP3764476B2 (ja) 2006-04-05
EP0728015A4 (fr) 1997-01-29
EP0728015B1 (fr) 2006-03-08
ES2260754T3 (es) 2006-11-01
US6432675B1 (en) 2002-08-13
JP2004121266A (ja) 2004-04-22
AU678371B2 (en) 1997-05-29
EP0728015A1 (fr) 1996-08-28
ATE319738T1 (de) 2006-03-15

Similar Documents

Publication Publication Date Title
DK0817846T3 (da) Intracellulært domæne af HER-2/neu proteinet til forebyggelse eller behandling af maligniteter
ATE228534T1 (de) Struktur höherer ordnung und bindung von peptidnukleinsäuren
DE69434475D1 (de) Impfstoff gegen prostatakrebs
DK0527760T3 (da) Fremgangsmåder og præparater til vaccination mod HIV
NO874510L (no) Fast rensemiddelblanding og anvendelse av denne.
NO166303C (no) Fremgangsmaate ved kvantitativ bestemmelse av protein c ogaktivatorpreparat til gjennomfoering av fremgangsmaaten.
DE3787515D1 (de) Verfahren zur On-Line-Vorausberechnung und -Kontrolle von alkoholischen Gärungen.
ATE101876T1 (de) Verfahren zur verringerung der heterogenitaet von monoklonalen antikoerpern.
DK0728015T3 (da) Kombinatoriske polypeptidantigener
ATE69108T1 (de) Elektrophoretisches gel hoher aufloesung sowie methode zur abscheidung von serumproteinen.
DE3765125D1 (de) Seismischer schwingungserzeuger zur kombinierten erregung von kompressions- und schubwellen.
DK41590D0 (da) Forbedrede protein c-molekyler samt fremgangsmaade til fremstilling og aktivering af samme
DK0538341T3 (da) EHV-4-gycoproteinvaccine.
DE3787706D1 (de) Verfahren zur quantitativen Bestimmung der Antigene und Antikörper.
ES8606411A1 (es) Procedimiento para la determinacion de fibrina
DE69133185D1 (de) Entwicklung von dns-sonden und immunologischen reagenzien von menschlichen tumor-assoziierten antigenen
DK267287A (da) Fremgangsmaade til kontrol af en elektromotors standsning, samt organ til af udfoere denne fremgangsmaade
ATE307201T1 (de) Srcr domäne-enthaltendes protein
DK0476059T3 (da) Fremgangsmåder til forøgelse af modificeringshastigheden for metastabile bindinger
DE3768306D1 (de) Verfahren zur fabrikation von n-(sulfonylmethyl)-formamiden und von sulfonylmethylisocyaniden.
DE69000909D1 (de) Transportables brueckenteil zur ueberwindung von graeben.
DE58907208D1 (de) Verfahren zur Bestimmung von Antikörpern.
ATE62019T1 (de) Verfahren zur herstellung von hcmvglykoproteinen, antikoerper dagegen und hcmvvakzine und dazu zu verwendende rekombinante vektoren.
DE3873255D1 (de) Methoden und praeparate zur vorbeugung von ulcera.
ATE12986T1 (de) Verfahren zur bestimmung von carcinoembryonalem antigen (cea) und zur bestimmung geeignete antikoerperloesung.