DK0716615T4 - Systemer til transdermal indgift med lav flux for höjvirksomme medikamenter - Google Patents

Systemer til transdermal indgift med lav flux for höjvirksomme medikamenter

Info

Publication number
DK0716615T4
DK0716615T4 DK94925757T DK94925757T DK0716615T4 DK 0716615 T4 DK0716615 T4 DK 0716615T4 DK 94925757 T DK94925757 T DK 94925757T DK 94925757 T DK94925757 T DK 94925757T DK 0716615 T4 DK0716615 T4 DK 0716615T4
Authority
DK
Denmark
Prior art keywords
low flux
transdermal administration
administration systems
efficacy
drugs
Prior art date
Application number
DK94925757T
Other languages
English (en)
Other versions
DK0716615T3 (da
Inventor
Chia-Ming Chiang
Eric J Roos
Tsung-Min Hsu
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22300358&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0716615(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK0716615T3 publication Critical patent/DK0716615T3/da
Publication of DK0716615T4 publication Critical patent/DK0716615T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK94925757T 1993-08-09 1994-08-05 Systemer til transdermal indgift med lav flux for höjvirksomme medikamenter DK0716615T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/104,414 US5554381A (en) 1993-08-09 1993-08-09 Low flux matrix system for delivering potent drugs transdermally
PCT/US1994/008883 WO1995004554A1 (en) 1993-08-09 1994-08-05 Low flux transdermal potent drug delivery system

Publications (2)

Publication Number Publication Date
DK0716615T3 DK0716615T3 (da) 2006-02-20
DK0716615T4 true DK0716615T4 (da) 2009-12-14

Family

ID=22300358

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94925757T DK0716615T4 (da) 1993-08-09 1994-08-05 Systemer til transdermal indgift med lav flux for höjvirksomme medikamenter

Country Status (13)

Country Link
US (1) US5554381A (da)
EP (1) EP0716615B2 (da)
JP (1) JPH09505554A (da)
AT (1) ATE309004T1 (da)
AU (1) AU679557B2 (da)
CA (1) CA2169164A1 (da)
DE (1) DE69434537T3 (da)
DK (1) DK0716615T4 (da)
ES (1) ES2249763T5 (da)
FI (1) FI960556A (da)
NO (1) NO960487D0 (da)
NZ (1) NZ271797A (da)
WO (1) WO1995004554A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
US5762956A (en) * 1996-04-24 1998-06-09 Rutgers, The State University Of New Jersey Transdermal contraceptive delivery system and process
AU2746397A (en) * 1996-04-30 1997-11-19 Theratech, Inc. Transdermal administration of steroid hormones using diethanolamides of c12-c18 fatty acids as permeation enhancers
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19830651A1 (de) * 1998-07-09 2000-01-13 Lohmann Therapie Syst Lts Steroidhaltiges Pflaster, Verfahren zu seiner Herstellung und Verwendung
US6337328B1 (en) 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
WO2002074286A1 (en) * 2001-03-16 2002-09-26 Alza Corporation Transdermal patch for administering fentanyl
US20050208117A1 (en) * 2001-03-16 2005-09-22 Venkatraman Subramanian S Transdermal administration of fentanyl and analogs thereof
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10141652B4 (de) * 2001-08-24 2011-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
CA2494915C (en) 2002-08-09 2012-07-10 Teikoku Seiyaku Co., Ltd. Female hormone-containing patch
DE60335490D1 (de) 2002-10-22 2011-02-03 Eisai R&D Man Co Ltd Spezifisch in postmitotischen dopamin-produzierenden neuronalen vorläuferzellen exprimiertes gen
DK1426049T3 (da) * 2002-12-02 2005-08-22 Sanol Arznei Schwarz Gmbh Iontophoretisk tilförsel af rotigotin til behandling af Parkinsons sygdom
DE10261696A1 (de) * 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
WO2006093139A1 (ja) * 2005-02-28 2006-09-08 Hisamitsu Pharmaceutical Co., Inc. 経皮吸収製剤
US8287923B2 (en) * 2005-06-10 2012-10-16 Medical College Of Georgia Research Institute, Inc. Compositions and methods for treating immune disorders
US9446017B2 (en) 2005-08-11 2016-09-20 Augusta University Research Institute, Inc. Compositions and methods for treating herpes simplex virus
US9114133B2 (en) 2006-08-25 2015-08-25 U.S. Dept. Of Veterans Affairs Method of improving diastolic dysfunction
US8672911B2 (en) 2007-08-03 2014-03-18 Kimberly-Clark Worldwide, Inc. Body adhering absorbent article
US7947027B2 (en) 2007-12-28 2011-05-24 Kimberly-Clark Worldwide, Inc. Body adhering absorbent article
US8734413B2 (en) 2007-08-03 2014-05-27 Kimberly-Clark Worldwide, Inc. Packaged body adhering absorbent article
RU2499583C2 (ru) * 2007-10-15 2013-11-27 Алза Корпорейшн Заместительное трансдермальное введение фентанила один раз в день
WO2009110351A1 (ja) 2008-03-03 2009-09-11 久光製薬株式会社 経皮吸収製剤
US11147722B2 (en) * 2008-11-10 2021-10-19 Kimberly-Clark Worldwide, Inc. Absorbent article with a multifunctional acrylate skin-adhesive composition
US10022468B2 (en) 2009-02-02 2018-07-17 Kimberly-Clark Worldwide, Inc. Absorbent articles containing a multifunctional gel
US20130017188A1 (en) 2009-07-31 2013-01-17 The Brigham And Women's Hospital, Inc. Modulation of sgk1 expression in th17 cells to modulate th17-mediated immune responses
EP2556082B1 (en) 2010-04-08 2017-02-22 Emory University Substituted androst-4-ene diones
WO2012129237A2 (en) 2011-03-20 2012-09-27 Trustees Of Boston University Therapeutic agent for emphysema and copd
WO2012151474A2 (en) 2011-05-04 2012-11-08 Trustees Of Boston University Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria
US20140227293A1 (en) 2011-06-30 2014-08-14 Trustees Of Boston University Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
EP2543370A1 (en) 2011-07-06 2013-01-09 Georgia Health Sciences University Research Institute, Inc. Compositions and Methods for Treating Herpes Simplex Virus
BR112014010670A2 (pt) * 2011-11-04 2017-05-09 Agile Therapeutics Inc composição para administração transdérmica de uma progestina, dispositivo de administração de droga transdérmica, e, método para melhorar a estabilidade de uma composição de administração transdérmica
US9243037B2 (en) 2011-11-10 2016-01-26 Trustees Of Boston College Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity
US20150366890A1 (en) 2013-02-25 2015-12-24 Trustees Of Boston University Compositions and methods for treating fungal infections
WO2015027146A1 (en) 2013-08-22 2015-02-26 The General Hospital Corporation Inhibitors of human 12/15-lipoxygenase
EP3038625A4 (en) 2013-08-29 2017-08-23 Trustees of Boston University Intermediate metabolism products to potentiate aminoglycoside antibiotics in bacterial infections
WO2016196664A1 (en) 2015-06-01 2016-12-08 Cedars-Sinai Medical Center Methods and use of compounds that bind to rela of nf-kb
RU2018107227A (ru) 2015-07-28 2019-08-28 Виоме Терапьютикс Лимитед Терапевтические и профилактические антибактериальные средства

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145682A (en) * 1986-05-30 1992-09-08 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration
US4906169A (en) * 1986-12-29 1990-03-06 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US5300291A (en) * 1988-03-04 1994-04-05 Noven Pharmaceuticals, Inc. Method and device for the release of drugs to the skin
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US5232703A (en) * 1989-07-21 1993-08-03 Izhak Blank Estradiol compositions and methods for topical application
JP2718433B2 (ja) * 1989-09-08 1998-02-25 シグナス インコーポレイテッド 経皮ドラッグデリバリーのための固体マトリックスシステム
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
DE3933460A1 (de) * 1989-10-06 1991-04-18 Lohmann Therapie Syst Lts Oestrogenhaltiges wirkstoffpflaster
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
JPH04342532A (ja) * 1991-05-21 1992-11-30 Sekisui Chem Co Ltd 経皮吸収貼付剤
IT1253265B (it) * 1991-11-25 1995-07-14 Rotta Research Lab Preparato a matrice copolimerica adesiva a base acrilica per il rilascio transdermico dell'estradiolo.

Also Published As

Publication number Publication date
EP0716615B1 (en) 2005-11-09
EP0716615A1 (en) 1996-06-19
ES2249763T5 (es) 2010-02-01
ES2249763T3 (es) 2006-04-01
CA2169164A1 (en) 1995-02-16
NZ271797A (en) 1997-12-19
US5554381A (en) 1996-09-10
AU7556294A (en) 1995-02-28
DE69434537T3 (de) 2010-04-15
DE69434537D1 (de) 2005-12-15
DK0716615T3 (da) 2006-02-20
JPH09505554A (ja) 1997-06-03
EP0716615A4 (en) 1997-06-11
DE69434537T2 (de) 2006-07-20
NO960487L (no) 1996-02-06
AU679557B2 (en) 1997-07-03
EP0716615B2 (en) 2009-10-21
FI960556A0 (fi) 1996-02-07
WO1995004554A1 (en) 1995-02-16
NO960487D0 (no) 1996-02-06
FI960556A (fi) 1996-03-11
ATE309004T1 (de) 2005-11-15

Similar Documents

Publication Publication Date Title
DK0716615T4 (da) Systemer til transdermal indgift med lav flux for höjvirksomme medikamenter
EP1737406B2 (en) Transdermal systems containing multilayer adhesive matrices to modify drug delivery
EP0033615B1 (en) Therapeutic system for administering drugs to the skin
US5314694A (en) Transdermal formulations, methods and devices
EP0279977A3 (en) Transdermal administration of progesterone, estradiol esters and mixtures thereof
KR900015761A (ko) 경피성 단일체 시스템
EP0737477A4 (en) TRANSDERMAL PHARMACEUTICAL PREPARATION
PL331239A1 (en) Drug base for transcutaneous concurrent administration of estradiol and some other steroid
CA2153572A1 (en) Transdermal therapeutic system with galanthamine as active ingredient
WO1992007589A1 (en) Transdermal contraceptive formulations, methods and devices
NZ240358A (en) Transdermal contraceptive device comprising (as active agents) an estrogen and a gestodene together with a skin permeation enhancer
HUT74455A (en) Pharmaceutical composition containing estradiol penetration intensifier agent for transdermal administration
EP0922453A3 (en) Percutaneous absorption type preparation containing tulobuterol
KR880010758A (ko) 서방성 제제
GR3018303T3 (en) Transdermal estradiol delivery system.
PL307786A1 (en) Plaster for percutaneous administration of systemically acting steroid hormones
EP2124907B1 (en) Transdermal patch and method for delivery of vitamin b12
WO1997020582A3 (en) Transdermal patch for comparative evaluations
ATE295157T1 (de) Mittel zur transdermalen verabreichung von arzneistoffen
EP2343963B1 (en) Transdermal delivery
WO2020046072A1 (ko) 장기 투여용 리바스티그민 패취
EP3845223A1 (en) Rivastigmine patch for long-term administration
KR950002749A (ko) 0차 흡수속도를 갖는 지속성 경피투여 제형 및 그 제조방법
TW273516B (en) Adhesive matrix-type transdermal therapeutic set for motion sickness