DK0693070T3 - Pyrido[2,3-b][1,4]benzodiazepinoner som M2-receptorligand til behandling af neurologiske lidelser - Google Patents

Pyrido[2,3-b][1,4]benzodiazepinoner som M2-receptorligand til behandling af neurologiske lidelser

Info

Publication number
DK0693070T3
DK0693070T3 DK94914039T DK94914039T DK0693070T3 DK 0693070 T3 DK0693070 T3 DK 0693070T3 DK 94914039 T DK94914039 T DK 94914039T DK 94914039 T DK94914039 T DK 94914039T DK 0693070 T3 DK0693070 T3 DK 0693070T3
Authority
DK
Denmark
Prior art keywords
treatment
neurological disorders
benzodiazepinones
pyrido
receptor ligand
Prior art date
Application number
DK94914039T
Other languages
Danish (da)
English (en)
Inventor
Bryan R Wilson
Christopher A Rhodes
R Tyler Mccabe
Original Assignee
Pharmaceutical Discovery Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaceutical Discovery Corp filed Critical Pharmaceutical Discovery Corp
Application granted granted Critical
Publication of DK0693070T3 publication Critical patent/DK0693070T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
DK94914039T 1993-04-05 1994-04-05 Pyrido[2,3-b][1,4]benzodiazepinoner som M2-receptorligand til behandling af neurologiske lidelser DK0693070T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4287293A 1993-04-05 1993-04-05
PCT/US1994/003720 WO1994022861A1 (fr) 1993-04-05 1994-04-05 PYRIDO[2,3-b][1,4]BENZODIAZEPINONES EN TANT QUE LIGAND DE RECEPTEUR M2 POUR LE TRAITEMENT DE TROUBLES NEUROLOGIQUES

Publications (1)

Publication Number Publication Date
DK0693070T3 true DK0693070T3 (da) 2002-11-11

Family

ID=21924192

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94914039T DK0693070T3 (da) 1993-04-05 1994-04-05 Pyrido[2,3-b][1,4]benzodiazepinoner som M2-receptorligand til behandling af neurologiske lidelser

Country Status (11)

Country Link
US (1) US5712269A (fr)
EP (2) EP0693070B1 (fr)
JP (1) JP3638950B2 (fr)
AT (1) ATE221067T1 (fr)
AU (1) AU688318B2 (fr)
CA (1) CA2159815A1 (fr)
DE (1) DE69431050T2 (fr)
DK (1) DK0693070T3 (fr)
ES (1) ES2180575T3 (fr)
PT (1) PT693070E (fr)
WO (1) WO1994022861A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
ITMI991452A1 (it) * 1999-07-01 2001-01-01 Mediolanum Farmaceutici Srl Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica
AR025884A1 (es) 1999-10-01 2002-12-18 Takeda Pharmaceutical Compuestos de amina ciclica, su produccion y su uso
WO2003089004A1 (fr) * 2002-04-19 2003-10-30 Takeda Pharmaceutical Company Limited Agents prophylactiques utilises pour prevenir l'infection par vih
JP5064216B2 (ja) 2004-07-16 2012-10-31 プロテオシス・アーゲー 炎症性疾患用治療剤としての、ｐａｒｐ及びｓｉｒ調節活性を有するムスカリンアンタゴニスト
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (fr) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
KR20200022525A (ko) * 2008-12-04 2020-03-03 충시 위 고투과력을 가진 조성물 및 이의 적용
WO2010081825A2 (fr) 2009-01-13 2010-07-22 Proteosys Ag Pirenzépine en tant qu'agent utilisé dans le traitement du cancer
GB201510010D0 (en) 2015-06-09 2015-07-22 King S College London PDD and BPD compounds
US20180339985A1 (en) 2015-08-21 2018-11-29 Femtogenix Limited Pdd compounds
GB201514928D0 (en) 2015-08-21 2015-10-07 King S College London PDD compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH438343A (de) * 1962-11-08 1967-06-30 Thomae Gmbh Dr K Verfahren zur Herstellung von 5,6-Dihydro-6-oxo-11H-pyrido (2,3-b) (1,4)-benzodiazepinen
DE3735895A1 (de) * 1987-10-23 1989-05-03 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3818299A1 (de) * 1988-05-30 1989-12-07 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB9000302D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Muscarinic receptor antagonists
DE4112014A1 (de) * 1991-04-12 1992-10-15 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung

Also Published As

Publication number Publication date
CA2159815A1 (fr) 1994-10-13
PT693070E (pt) 2002-12-31
JP3638950B2 (ja) 2005-04-13
JPH08510999A (ja) 1996-11-19
EP0693070B1 (fr) 2002-07-24
ATE221067T1 (de) 2002-08-15
DE69431050T2 (de) 2003-03-13
EP1120416A1 (fr) 2001-08-01
ES2180575T3 (es) 2003-02-16
WO1994022861A1 (fr) 1994-10-13
DE69431050D1 (de) 2002-08-29
AU6626194A (en) 1994-10-24
AU688318B2 (en) 1998-03-12
EP0693070A1 (fr) 1996-01-24
US5712269A (en) 1998-01-27

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