DK0689550T3 - Antimikrobielle peptider fra bovine neutrofile - Google Patents

Antimikrobielle peptider fra bovine neutrofile

Info

Publication number
DK0689550T3
DK0689550T3 DK94912855T DK94912855T DK0689550T3 DK 0689550 T3 DK0689550 T3 DK 0689550T3 DK 94912855 T DK94912855 T DK 94912855T DK 94912855 T DK94912855 T DK 94912855T DK 0689550 T3 DK0689550 T3 DK 0689550T3
Authority
DK
Denmark
Prior art keywords
antimicrobial peptides
neutrophils
bovine neutrophils
rich
purified
Prior art date
Application number
DK94912855T
Other languages
English (en)
Inventor
Michael E Selsted
James S Cullor
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK0689550T3 publication Critical patent/DK0689550T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK94912855T 1993-03-19 1994-03-15 Antimikrobielle peptider fra bovine neutrofile DK0689550T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/033,873 US5459235A (en) 1993-03-19 1993-03-19 Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
PCT/US1994/003178 WO1994021672A1 (en) 1993-03-19 1994-03-15 Novel antimicrobial peptides from bovine neutrophils

Publications (1)

Publication Number Publication Date
DK0689550T3 true DK0689550T3 (da) 2003-03-17

Family

ID=21872945

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94912855T DK0689550T3 (da) 1993-03-19 1994-03-15 Antimikrobielle peptider fra bovine neutrofile

Country Status (12)

Country Link
US (3) US5459235A (da)
EP (1) EP0689550B1 (da)
JP (1) JPH08508165A (da)
KR (1) KR960701093A (da)
AT (1) ATE227308T1 (da)
AU (1) AU679739B2 (da)
CA (1) CA2155739A1 (da)
DE (1) DE69431654T2 (da)
DK (1) DK0689550T3 (da)
ES (1) ES2186684T3 (da)
PT (1) PT689550E (da)
WO (1) WO1994021672A1 (da)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844072A (en) * 1992-05-26 1998-12-01 University Of California Antibiotic cryptdin peptides and methods of their use
US4304715A (en) * 1979-06-08 1981-12-08 Derek Hudson Enkephalin analogues
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
US5912230A (en) * 1991-11-01 1999-06-15 Periodontix, Inc. Anti-fungal and anti-bacterial histatin-based peptides
US5646119A (en) * 1991-11-01 1997-07-08 Periodontix, Inc. D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents
US5631228A (en) * 1991-11-01 1997-05-20 Periodontix, Inc. Anti-fungal and anti-bacterial histatin-based peptides
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US6653442B1 (en) 1993-07-20 2003-11-25 Intrabiotics Pharmaceuticals, Inc. Protegrins
US6159936A (en) * 1993-07-20 2000-12-12 The Regents Of The University Of California Compositions and methods for treating and preventing microbial and viral infections
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
AU4865796A (en) * 1995-02-17 1996-09-04 Allergan, Inc. Ophthalmic compositions including peptides and peptide derivatives and methods for using same
US6025326A (en) * 1995-07-07 2000-02-15 Intrabiotics Pharmaceuticals, Inc. Compositions and methods for the prevention and treatment of oral mucositis
US5994306A (en) * 1995-11-22 1999-11-30 Intrabiotics Pharmaceuticals, Inc. Fine-tuned protegrins
JP4001383B2 (ja) * 1995-12-16 2007-10-31 プラントン・ゲゼルシヤフト・ミット・ベシュレンクテル・ハフツング 細菌、菌類、およびウイルスに対して有効で、かつ脊椎動物性蛋白質を含む化粧用製剤
WO1997029765A1 (en) * 1996-02-16 1997-08-21 The Regents Of The University Of California Antimicrobial peptides and methods of use
US5916872A (en) * 1996-07-24 1999-06-29 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity
US6174664B1 (en) 1997-02-05 2001-01-16 University Of Pittsburgh Screening method for inflammatory diseases using neutrophil defensins and lactoferrin
US5972594A (en) * 1997-02-05 1999-10-26 University Of Pittsburgh Method for screening for reproductive tract inflammation and preeclampsia using neutrophil defensins
FR2767832B1 (fr) 1997-08-29 2001-08-10 Genset Sa Polypeptide defensine humaine def-x, adn genomique et adnc, composition les contenant et applications au diagnostic et au traitement therapeutique
US6531573B1 (en) 1997-12-18 2003-03-11 Trustees Of Boston University Antifungal and antibacterial peptides
CA2296022A1 (en) * 1998-02-06 1999-08-26 University Of Pittsburgh Screening method for reproductive tract inflammation and preeclampsia using neutrophil defensins
US6545140B1 (en) 1998-07-13 2003-04-08 University Of Georgia Research Foundation, Inc. DNA encoding an avian beta-defensin and uses thereof
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
WO2002014346A2 (en) * 2000-08-15 2002-02-21 North Carolina State University Antimicrobial peptides isolated from fish
US6753407B2 (en) 2000-08-15 2004-06-22 North Carolina State University Antimicrobial peptides isolated from fish
ATE328491T1 (de) * 2000-10-24 2006-06-15 Campina Melkunie Bv Peptiden reich an cystein und/oder glycin
US7314858B2 (en) * 2001-04-18 2008-01-01 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
CA2444626A1 (en) * 2001-04-18 2002-10-31 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US6713078B2 (en) 2001-04-18 2004-03-30 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US6835536B2 (en) * 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US7511015B2 (en) * 2002-02-19 2009-03-31 The United States Of America As Represented By The Department Of Health And Human Services Modified defensins and their use
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
US20040136926A1 (en) * 2002-11-08 2004-07-15 Periathamby Antony Raj Intra-oral drug delivery system
GB0300597D0 (en) 2003-01-10 2003-02-12 Microbiological Res Authority Phage biofilms
EP1663265B1 (en) 2003-07-23 2015-09-23 Biocontrol Limited Bacteriophage-containing therapeutic agents
US20060008466A1 (en) * 2004-07-07 2006-01-12 University Of Saskatchewan Methods for treating and preventing microbial infections
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
US20060217306A1 (en) * 2005-02-08 2006-09-28 Novozymes A/S Systemic treatment of infections with defensins
GB0704553D0 (en) 2007-03-09 2007-04-18 Harper David R Beneficial effects of bacteriophage treatments
GB0821707D0 (en) * 2008-11-28 2008-12-31 Secr Defence Peptides
GB0821687D0 (en) 2008-11-28 2008-12-31 Secr Defence Peptides
WO2013039861A2 (en) 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
HK1206612A1 (en) 2012-04-02 2016-01-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of secreted proteins
HK1206638A1 (en) 2012-04-02 2016-01-15 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
KR20180101341A (ko) 2015-11-10 2018-09-12 비스테라, 인크. 리포폴리사카라이드에 특이적으로 결합하는 항체 분자-약물 접합체 및 그의 용도
JP7303110B2 (ja) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
CN116710146A (zh) 2020-04-03 2023-09-05 威特拉公司 抗体分子-药物偶联物及其用途
US11713341B1 (en) 2022-06-17 2023-08-01 Vestaron Corporation Antimicrobial NCR13 variant peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202420A (en) * 1990-10-25 1993-04-13 The Children's Hospital Of Philadelphia Tracheal antimicrobial peptides, dna sequences and methods for the production and use thereof
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5635594A (en) * 1994-03-11 1997-06-03 University Of California, Los Angeles Gallinacins - antibiotic peptides
US5550109A (en) * 1994-05-24 1996-08-27 Magainin Pharmaceuticals Inc. Inducible defensin peptide from mammalian epithelia

Also Published As

Publication number Publication date
PT689550E (pt) 2003-03-31
ES2186684T3 (es) 2003-05-16
KR960701093A (ko) 1996-02-24
EP0689550A4 (en) 1998-01-07
AU6523994A (en) 1994-10-11
EP0689550A1 (en) 1996-01-03
CA2155739A1 (en) 1994-09-29
US5459235A (en) 1995-10-17
DE69431654T2 (de) 2003-07-17
AU679739B2 (en) 1997-07-10
US5821224A (en) 1998-10-13
ATE227308T1 (de) 2002-11-15
WO1994021672A1 (en) 1994-09-29
EP0689550B1 (en) 2002-11-06
DE69431654D1 (de) 2002-12-12
JPH08508165A (ja) 1996-09-03
US6211148B1 (en) 2001-04-03

Similar Documents

Publication Publication Date Title
DK0689550T3 (da) Antimikrobielle peptider fra bovine neutrofile
ATE202785T1 (de) Verbindungen mit wachstumshormon-freisetzenden eigenschaften
DK0749317T3 (da) Terapeutiske anvendelser af dimerprodukter af baktericidt/permeabilitetsforøgende protein
DE68927189D1 (de) Arzneimittel, die Lanthionin enthaltenden Bacteriozin enthalten, zur Verwendung als Bakterizide
DK0654078T3 (da) Thrombinblodfraktion til anvendelse i en medicinsk procedure
BR9801126A (pt) 1,4-benzotiazepina-1,1-dióxidos hipolipidêmicos.
DE69030212D1 (de) Verwendung von Derivaten des 4-Phenyl-1,2,3,4-tetrahydro-1-naphthalenamins zur Behandlung von Psychose, Entzündung und als Immununterdrücker
MX9305729A (es) Formulas de proteinas de liberacion sostenida.
EP0497904A4 (en) Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins, and their use
ATE114113T1 (de) Verwendung von droloxifen bei der behandlung von knochenerkrankungen.
BR8707672A (pt) Pirazolinas inseticidas
IL113941A (en) Perfluoroalkyl ketone inhibitors of elastase processes for making the same and pharmaceutical compositions containing them
ATE108662T1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
DK0695171T3 (da) Lyosfærer indeholdende gonadotropin
ITMI931649A1 (it) Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico
PH25313A (en) Carboxylic acid derivatives, pharmaceutical compositions containing them
DK0613499T4 (da) Humane IT-4-mutantproteiner
ES2192779T3 (es) Modificacion cristalina de 1-(2,6-difluorbencil)-1h-1,2,3-triazol-4-carboxamida y su uso como antiepileptico.
ATE285786T1 (de) Säugetierabkömmliche peptide zur behandlung von mikrobiellen infektionen
DE69327693D1 (de) Interferon-Alpha/Beta bindendes Protein, seine Herstellung und seine enthaltende pharmazeutische Zusammensetzungen
ATE100713T1 (de) L-alpha-glycerophosphoryl-d-myoinositol zur behandlung peripherer neuropathien und cerebropathien.
DK0722460T3 (da) Peptidderivater der er terapeutisk aktive i blodkoaguleringskaskaden, fremgangsmåde til fremstilling heraf og farmaceutiske
Sutton et al. Purification and sequencing of glycosylation variants of BSF-1, as a MAF, from the EL-4 leukaemia cell line
CO4230067A1 (es) Composicion cosmetica para el cuidado de la piel
ES2081255B1 (es) Aplicacion de las proteinas receptoras de autoincompatibilidad (slsg) de plantas para el tratamiento de las enfermedades alergicas.