DK0689434T3 - Farmaceutiske præparater, der omfatter paracetamol og L-cystein eller en præcursor deraf - Google Patents

Farmaceutiske præparater, der omfatter paracetamol og L-cystein eller en præcursor deraf

Info

Publication number
DK0689434T3
DK0689434T3 DK94908449T DK94908449T DK0689434T3 DK 0689434 T3 DK0689434 T3 DK 0689434T3 DK 94908449 T DK94908449 T DK 94908449T DK 94908449 T DK94908449 T DK 94908449T DK 0689434 T3 DK0689434 T3 DK 0689434T3
Authority
DK
Denmark
Prior art keywords
cysteine
precursor
paracetamol
pharmaceutical compositions
hydroxyacetanilide
Prior art date
Application number
DK94908449T
Other languages
English (en)
Inventor
Roger Spencer Jones
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Application granted granted Critical
Publication of DK0689434T3 publication Critical patent/DK0689434T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK94908449T 1993-03-12 1994-03-08 Farmaceutiske præparater, der omfatter paracetamol og L-cystein eller en præcursor deraf DK0689434T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939305058A GB9305058D0 (en) 1993-03-12 1993-03-12 Pharmaceutical compositions
PCT/GB1994/000446 WO1994020086A1 (en) 1993-03-12 1994-03-08 Pharmaceutical compositions comprising paracetamol and l-cysteine or a precursor thereof

Publications (1)

Publication Number Publication Date
DK0689434T3 true DK0689434T3 (da) 2002-12-02

Family

ID=10731916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94908449T DK0689434T3 (da) 1993-03-12 1994-03-08 Farmaceutiske præparater, der omfatter paracetamol og L-cystein eller en præcursor deraf

Country Status (20)

Country Link
US (2) US5716991A (da)
EP (2) EP1210939B1 (da)
JP (1) JPH08507305A (da)
KR (1) KR960700701A (da)
CN (1) CN1118989A (da)
AT (2) ATE314842T1 (da)
AU (1) AU674934B2 (da)
BR (1) BR9406227A (da)
CA (1) CA2157921C (da)
DE (2) DE69434600T2 (da)
DK (1) DK0689434T3 (da)
ES (2) ES2254541T3 (da)
GB (2) GB9305058D0 (da)
IL (1) IL108937A (da)
NO (1) NO318493B1 (da)
NZ (1) NZ262168A (da)
PT (1) PT689434E (da)
SG (1) SG48344A1 (da)
WO (1) WO1994020086A1 (da)
ZA (1) ZA941674B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5882298A (en) * 1997-01-29 1998-08-18 Chong Kun Dang Corporation New analgesic composition
WO2001068069A2 (en) * 2000-03-15 2001-09-20 King's College London Pharmaceutical composition comprising paracetamol
KR100379155B1 (ko) * 2000-07-18 2003-04-08 삼진제약주식회사 새로운 진통제 조성물
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
US20080188439A1 (en) * 2006-10-26 2008-08-07 Salhanick Steven D Directed metabolism of compounds by glucuronidation and sulfonation donors to decrease toxicity
ITMI20080187A1 (it) * 2008-02-07 2009-08-08 Velleja Res Srl Formulazioni di amminoacidi per la prevenzione del danno epatico da paracetamolo
CA2767833C (en) * 2009-07-15 2018-10-23 Leland Stanford, The Board Of Trustees Of The Junior University N-acetyl cysteine compositions and methods to improve the therapeutic efficacy of acetaminophen
ITMI20130874A1 (it) * 2013-05-29 2014-11-30 Zambon Spa Compresse deglutibili di n-acetilcisteina

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200039A (en) * 1962-05-28 1965-08-10 Pfizer & Co C Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu
GB1287431A (en) * 1969-04-16 1972-08-31 Aspro Nicholas Ltd Improvements in pharmaceutical formulations
GB1390032A (en) * 1971-08-27 1975-04-09 Sterling Winthrop Group Ltd Pharmaceutical compositions
GB1410909A (en) * 1971-10-26 1975-10-22 Sterling Winthrop Group Ltd Pharmaceutical compositions
GB1463505A (en) * 1973-11-21 1977-02-02 Nat Res Dev Pharmaceutical compositions
GB1583602A (en) * 1977-05-26 1981-01-28 Sterwin Ag N-acetyl-para-aminophenyl-n'-acetyl-amino-thioalkanoic acid ester derivatives
ATE17650T1 (de) * 1980-05-20 1986-02-15 Mallinckrodt Inc Trockenpulverisierte n-acetyl-p-aminophenolzusammensetzungenund verfahren zu deren herstellung.
US4439453A (en) * 1980-12-22 1984-03-27 Monsanto Company Directly compressible acetaminophen granulation
GR79340B (da) * 1982-07-06 1984-10-22 Sterwin Ag
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4760093A (en) * 1986-10-21 1988-07-26 American Home Products Corporation (Del.) Spray dried acetaminophen
US5037658A (en) * 1989-09-14 1991-08-06 Hoechst-Roussel Pharmaceuticals, Inc. Direct dry compressible acetaminophen composition
ES2077757T5 (es) * 1990-10-19 2001-06-01 Spirig Ag Pharmazeutische Prap Preparacion farmaceutica solida con disolucion rapida que contiene la n-acetilcisteina.
US5474757A (en) * 1992-10-16 1995-12-12 Rutgers University Prevention of acetaminophen overdose toxicity with organosulfur compounds
FR2708602B1 (fr) * 1993-08-02 1995-10-06 Oreal Procédé d'extraction des composés malodorants présents dans une formulation contenant au moins un composé comportant un groupe thiol et compositions désodorisées ainsi obtenues.
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
JPH07130367A (ja) * 1993-10-29 1995-05-19 Sony Corp リチウム二次電池用正極活物質の製造方法

Also Published As

Publication number Publication date
ATE314842T1 (de) 2006-02-15
ATE221777T1 (de) 2002-08-15
EP0689434B1 (en) 2002-08-07
JPH08507305A (ja) 1996-08-06
AU6148794A (en) 1994-09-26
CN1118989A (zh) 1996-03-20
KR960700701A (ko) 1996-02-24
CA2157921A1 (en) 1994-09-15
EP1210939A2 (en) 2002-06-05
NZ262168A (en) 1997-05-26
GB9404427D0 (en) 1994-04-20
IL108937A0 (en) 1994-06-24
NO953515D0 (no) 1995-09-07
US5716991A (en) 1998-02-10
GB2276319B (en) 1997-01-15
US5852055A (en) 1998-12-22
EP1210939B1 (en) 2006-01-04
GB2276319A (en) 1994-09-28
DE69431151T2 (de) 2002-12-12
BR9406227A (pt) 1995-12-12
IL108937A (en) 1999-10-28
ZA941674B (en) 1995-09-11
PT689434E (pt) 2002-12-31
WO1994020086A1 (en) 1994-09-15
DE69431151D1 (de) 2002-09-12
AU674934B2 (en) 1997-01-16
NO953515L (no) 1995-09-07
DE69434600T2 (de) 2006-08-24
CA2157921C (en) 2006-07-11
ES2176238T3 (es) 2002-12-01
NO318493B1 (no) 2005-03-29
ES2254541T3 (es) 2006-06-16
GB9305058D0 (en) 1993-04-28
EP1210939A3 (en) 2002-08-07
EP0689434A1 (en) 1996-01-03
SG48344A1 (en) 1998-04-17
DE69434600D1 (de) 2006-03-30

Similar Documents

Publication Publication Date Title
FI906438A0 (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi
YU48666B (sh) Mometason furoat monohidrat i postupak za njegovo dobijanje
BR0010952A (pt) Material de revestimento com uma mistura de ácidos silìcicos e uréia e/ou derivados de uréia
AU588837B2 (en) Polypeptide
MX9700273A (es) Benzamidinas sustituidas, su preparacion y empleo como sustancias medicamentosas.
DK0689434T3 (da) Farmaceutiske præparater, der omfatter paracetamol og L-cystein eller en præcursor deraf
DE69910113D1 (de) Verfahren zur Herstellung von Stickstofftrifluorid durch Gas-Feststoffreaktion
HUT54988A (en) Process for producing substituted n-(quinolin-2-ylmethoxy)-benzylsulfonylureas and pharmaceutical compositions comprising such compounds
ATE482226T1 (de) Synthese von derivaten der 2-deoxy-2-fluoro- arabinose
PT88551A (pt) Process for the preparation of curable compositions suitable for use as sealants
DK285082A (da) Acaricidt praeparat dets fremstilling og anvendelse
BR8605037A (pt) Processo para a preparacao de uma composicao pesticida liquida
AU561513B2 (en) Carbamates and oxalamides of ammo-n-(1h-tetrazol-5-yl) benzamides
KR920016441A (ko) 글리세르알데하이드-3-펜타나이드 및 이의 제조방법
ECSP951385A (es) Composiciones farmaceuticas paracetamol con metionina
FI903950A0 (fi) Ny komposition.
JPS6419063A (en) Novel heterocyclic compound and use thereof
HUT57746A (en) Process for producing new 1,3-oxazines and pharmaceutical compositions comprising same