ES2077757T5 - Preparacion farmaceutica solida con disolucion rapida que contiene la n-acetilcisteina. - Google Patents

Preparacion farmaceutica solida con disolucion rapida que contiene la n-acetilcisteina.

Info

Publication number
ES2077757T5
ES2077757T5 ES91116899T ES91116899T ES2077757T5 ES 2077757 T5 ES2077757 T5 ES 2077757T5 ES 91116899 T ES91116899 T ES 91116899T ES 91116899 T ES91116899 T ES 91116899T ES 2077757 T5 ES2077757 T5 ES 2077757T5
Authority
ES
Spain
Prior art keywords
pharmaceutical preparation
solid pharmaceutical
acetylcisteine
quick dissolution
dissolution containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91116899T
Other languages
English (en)
Other versions
ES2077757T3 (es
Inventor
Rolf-Dieter Juch
Gerd Dr Birrenbach
Christian Dr Pflugshaupt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spirig Pharma AG
Original Assignee
Spirig AG Pharmazeutische Praeparate
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4253965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2077757(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Spirig AG Pharmazeutische Praeparate filed Critical Spirig AG Pharmazeutische Praeparate
Application granted granted Critical
Publication of ES2077757T3 publication Critical patent/ES2077757T3/es
Publication of ES2077757T5 publication Critical patent/ES2077757T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PREPARACION DE ALIMENTOS SOLIDOS Y COMPACTOS QUE CONTIENEN CISTEINA ACETILA DE N Y/O CISTEINA S-(CARBOXIMETILO)-L ES ADECUADA PARA TRAGAR, CHUPAR O PARA DISOLVERLAS EN AGUA O EN UNA SOLUCION ACUOSA, A PESAR DE QUE TIENE UNA PEQUEÑA PARTE DE SUSTANCIAS AUXILIARES. ESTOS MEDICAMENTOS SON TAN COMPACTOS DEBIDO A QUE TIENE UNA GRAN PARTE DE SUSTANCIAS ACTIVAS, DE MAS DEL 50% DE PESO DEL PESO TOTAL Y MEDIANTE LA ELECCION APROPIADA DE MEDIOS AUXILIARES DE PASTILLAS.
ES91116899T 1990-10-19 1991-10-04 Preparacion farmaceutica solida con disolucion rapida que contiene la n-acetilcisteina. Expired - Lifetime ES2077757T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH334590 1990-10-19

Publications (2)

Publication Number Publication Date
ES2077757T3 ES2077757T3 (es) 1995-12-01
ES2077757T5 true ES2077757T5 (es) 2001-06-01

Family

ID=4253965

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91116899T Expired - Lifetime ES2077757T5 (es) 1990-10-19 1991-10-04 Preparacion farmaceutica solida con disolucion rapida que contiene la n-acetilcisteina.

Country Status (7)

Country Link
US (1) US5401514A (es)
EP (1) EP0481294B2 (es)
AT (1) ATE125702T1 (es)
DE (1) DE59106133D1 (es)
DK (1) DK0481294T4 (es)
ES (1) ES2077757T5 (es)
GR (1) GR3017499T3 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1256616B (it) * 1992-12-02 1995-12-12 Zambon Spa Sciroppo contenente n-acetil-cisteina
US5807894A (en) * 1992-12-02 1998-09-15 Zambon Group S.P.A. Syrup containing N-acetyl-cysteine
GB9305058D0 (en) * 1993-03-12 1993-04-28 Penn Pharm Ltd Pharmaceutical compositions
SE9601527D0 (sv) 1996-04-23 1996-04-23 Pharmacia Ab Transdermally alministered acetylcysteine as mucolytic agent
DE839528T1 (de) * 1996-10-29 1998-10-22 Staroil Ltd Mundlösliche Zusammensetzungen die N-Acetylcystein und Cyclodextrin enthalten
US6296868B1 (en) 1998-11-19 2001-10-02 Advanced Technology Pharmaceuticals Corporation Chewable tablets containing mannitol and aspartame
IT1311907B1 (it) * 1999-04-06 2002-03-20 Zambon Spa Compresse deglutibili ad alto contenuto di n-acetilcisteina.
US7510728B2 (en) * 2000-10-06 2009-03-31 Takeda Pharmaceutical Company Limited Solid preparations
WO2002041887A1 (fr) * 2000-11-21 2002-05-30 Kyorin Pharmaceutical Co., Ltd. Preparations seches de sirop
AR032556A1 (es) * 2001-02-08 2003-11-12 Pharmacia Corp Medicamento de accion inmediata para el tratamiento de la disfuncion sexual
CA2500919A1 (en) * 2002-10-04 2004-04-22 Pharmacia Corporation Compositions and methods for treating sexual dysfunction
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US7790928B1 (en) * 2005-04-25 2010-09-07 Albert Raymond Hechinger Therapeutic dimethyl sulfoxide (aka DMSO) compositions and methods of use
WO2009137827A2 (en) * 2008-05-09 2009-11-12 Tiara Pharmaceuticals, Inc. Controlled release of n-acetylcysteine (nac) for reduction of systemic and/or vascular inflammation
US20100120776A1 (en) * 2008-11-12 2010-05-13 Hall Bioscience Corporation Carbocysteine medical foods
TR200900881A2 (tr) 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş stabil farmasötik bileşimler
TR200900882A2 (tr) 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş, bıyoyararlanımı yüksek farmasotık bileşimler.
US8293299B2 (en) 2009-09-11 2012-10-23 Kraft Foods Global Brands Llc Containers and methods for dispensing multiple doses of a concentrated liquid, and shelf stable Concentrated liquids
US11013248B2 (en) 2012-05-25 2021-05-25 Kraft Foods Group Brands Llc Shelf stable, concentrated, liquid flavorings and methods of preparing beverages with the concentrated liquid flavorings
ITMI20130874A1 (it) * 2013-05-29 2014-11-30 Zambon Spa Compresse deglutibili di n-acetilcisteina
FI2886108T4 (fi) 2013-12-23 2023-02-22 Optimoitu farmaseuttinen koostumus ruokatorven tulehduksellisten muutosten hoitoon
RU2611411C1 (ru) * 2016-01-11 2017-02-21 Общество с ограниченной ответственностью "Трейдсервис" Диспергируемая в воде таблетка ацетилцистеина и способ ее изготовления
CN108553439B (zh) * 2018-04-20 2020-10-16 广州白云山医药集团股份有限公司白云山制药总厂 一种含s-羧甲基-l-半胱氨酸的肠溶片剂
PH12018000390A1 (en) * 2018-11-20 2020-09-28 Novex Science Pte Ltd Carbocysteine and zinc tablet
WO2020186161A2 (en) * 2019-03-13 2020-09-17 The Regents Of The University Of California Compositions and methods for regulating uterine and placental growth

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2437834A1 (fr) * 1978-10-04 1980-04-30 Lejeune Jerome Compositions pharmaceutiques a base de l-serine ou de glycine
HU180443B (en) * 1979-04-02 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a pharmaceutical preparation with synergetic action against radiation
NL8502092A (nl) * 1985-07-22 1987-02-16 Cedona Haarlemmer Pharma Tabletten die s-carboxymethylcysteine bevatten en werkwijze voor de bereiding daarvan.
ES2061623T3 (es) * 1987-03-02 1994-12-16 Brocades Pharma Bv Procedimiento para la obtencion de una composicion farmaceutica y un granulado farmaceutico.
IT1217445B (it) * 1988-04-29 1990-03-22 Altergon Sa Composizione farmaceutiche orosolubili contenti acetilcisteina
CH674940A5 (es) * 1988-05-05 1990-08-15 Ibsa Inst Biochimique Sa
SE462779B (sv) * 1988-10-10 1990-09-03 Lejus Medical Ab Farmaceutisk komposition innehaallande n-acetylcystein i en kaerna belagd med hydroxipropylmetylcellulosaftalat

Also Published As

Publication number Publication date
EP0481294B1 (de) 1995-08-02
US5401514A (en) 1995-03-28
ATE125702T1 (de) 1995-08-15
DK0481294T4 (da) 2001-06-18
EP0481294A1 (de) 1992-04-22
EP0481294B2 (de) 2001-04-11
GR3017499T3 (en) 1995-12-31
DK0481294T3 (da) 1995-11-27
ES2077757T3 (es) 1995-12-01
DE59106133D1 (de) 1995-09-07

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