GB1390032A - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- GB1390032A GB1390032A GB4042771A GB4042771A GB1390032A GB 1390032 A GB1390032 A GB 1390032A GB 4042771 A GB4042771 A GB 4042771A GB 4042771 A GB4042771 A GB 4042771A GB 1390032 A GB1390032 A GB 1390032A
- Authority
- GB
- United Kingdom
- Prior art keywords
- weight
- component
- aug
- ester
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1390032 Paracetamol formulations STERLING-WINTHROP GROUP Ltd 23 Nov 1972 [27 Aug 1971 29 Aug 1972] 40427/71 and 40075/72 Heading A5B A free-flowing granular material, suitable for tabletting and comprising (a) more than 80% by weight of an N-acylaminophenol or an ester thereof and (b) from 1.5% to 10% by weight, on the weight of component (a), of a water-soluble polymeric organic binder, may be prepared by spray-drying an aqueous fluid comprising (a) and (b). The material preferably has a water content of from 0.4% to 2.0% by weight. Component (a) may be paracetamol, metacetamol or the acetylsalicylic ester thereof and component (b) may be polyvinylpyrrolidone, polyvinyl alcohol, a copolymer of vinyl alcohol, vinyl acetate and/or vinyl pyrrolidone, or a cellulose derivative such as hydroxyethyl-, hydroxypropyl- and sodium carboxymethyl cellulose. The material may also comprise up to 7% by weight on the weight of component a) of a starch or derivative thereof or a sugar or sugar alcohol e.g. maize starch, dextrin, glucose, sucrose, sorbitol or mannitol; and/or a preservative for component (a) e.g. potassium sorbate or benzoic acid or its derivatives.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4042771A GB1390032A (en) | 1971-08-27 | 1971-08-27 | Pharmaceutical compositions |
ZA725791A ZA725791B (en) | 1971-08-27 | 1972-08-22 | Granular material suitable for tabletting free-flowing comprising n-acylamino-phenol and water-soluble polymeric organic binder |
AU45845/72A AU4584572A (en) | 1971-08-27 | 1972-08-22 | Free-flowing granular material |
DK423272AA DK131418B (en) | 1971-08-27 | 1972-08-25 | Method for preparing and optionally tableting a free-flowing granular material suitable for tableting. |
CA150,153A CA988424A (en) | 1971-08-27 | 1972-08-25 | Pharmaceutical compositions of n-acylaminophenol in a suitable form for tabletting |
DE2241960A DE2241960C2 (en) | 1971-08-27 | 1972-08-25 | Free-flowing granules for tablet production |
FR7230504A FR2150903B1 (en) | 1971-08-27 | 1972-08-28 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4042771A GB1390032A (en) | 1971-08-27 | 1971-08-27 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1390032A true GB1390032A (en) | 1975-04-09 |
Family
ID=10414863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4042771A Expired GB1390032A (en) | 1971-08-27 | 1971-08-27 | Pharmaceutical compositions |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU4584572A (en) |
CA (1) | CA988424A (en) |
DE (1) | DE2241960C2 (en) |
DK (1) | DK131418B (en) |
FR (1) | FR2150903B1 (en) |
GB (1) | GB1390032A (en) |
ZA (1) | ZA725791B (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5753403A (en) * | 1980-05-20 | 1982-03-30 | Mallinckrodt Chemical Works | Composition containing spray dry particle of n-acetyl-p-aminophenol and manufacture |
US4562024A (en) * | 1982-07-06 | 1985-12-31 | Sterling Drug Inc. | Process for preparing granulate containing poorly compressible medicinally active matter |
US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
US4631284A (en) * | 1984-11-19 | 1986-12-23 | Mallinckrodt, Inc. | Acetaminophen compositions containing low doses of chlorpheniramine maleate, method for preparing same and tablets formed therefrom |
US4661521A (en) * | 1984-04-30 | 1987-04-28 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
AU574345B2 (en) * | 1982-07-06 | 1988-07-07 | Sterling Drug Inc. | Preparing compressed tablets by wet granulation and tablets therefrom |
US4757090A (en) * | 1986-07-14 | 1988-07-12 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
WO1989002266A1 (en) * | 1987-09-17 | 1989-03-23 | Mallinckrodt, Inc. | A free-flowing granular composition containing ibuprofen and a method for its preparation |
WO1994020086A1 (en) * | 1993-03-12 | 1994-09-15 | British Technology Group Limited | Pharmaceutical compositions comprising paracetamol and l-cysteine or a precursor thereof |
US9724302B2 (en) | 2010-04-09 | 2017-08-08 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR226763A1 (en) * | 1980-12-22 | 1982-08-13 | Monsanto Co | PREPARATION METHOD FOR AN ANALGESIC GRANULATION OF ACETAMINOPHEN |
DE3215211A1 (en) * | 1982-04-23 | 1983-10-27 | Akzo Gmbh | MICROPOROISIS POWDER LOADED WITH ACTIVE SUBSTANCES |
DE3447422A1 (en) * | 1984-12-24 | 1986-06-26 | Basf Ag, 6700 Ludwigshafen | METHOD FOR THE PRODUCTION OF ASCORBIN ACID GRANULES |
JPH0780754B2 (en) * | 1986-08-06 | 1995-08-30 | エーザイ株式会社 | Multi-granular sustained-release tablet |
US4820522A (en) * | 1987-07-27 | 1989-04-11 | Mcneilab, Inc. | Oral sustained release acetaminophen formulation and process |
DE19835124C2 (en) * | 1998-08-04 | 2002-01-03 | Buna Sow Leuna Olefinverb Gmbh | Process for the production of starch esters with a defined grain structure for pharmaceutical purposes |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3200039A (en) * | 1962-05-28 | 1965-08-10 | Pfizer & Co C | Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu |
-
1971
- 1971-08-27 GB GB4042771A patent/GB1390032A/en not_active Expired
-
1972
- 1972-08-22 ZA ZA725791A patent/ZA725791B/en unknown
- 1972-08-22 AU AU45845/72A patent/AU4584572A/en not_active Expired
- 1972-08-25 DE DE2241960A patent/DE2241960C2/en not_active Expired
- 1972-08-25 CA CA150,153A patent/CA988424A/en not_active Expired
- 1972-08-25 DK DK423272AA patent/DK131418B/en not_active IP Right Cessation
- 1972-08-28 FR FR7230504A patent/FR2150903B1/fr not_active Expired
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0354083B2 (en) * | 1980-05-20 | 1991-08-19 | ||
JPS5753403A (en) * | 1980-05-20 | 1982-03-30 | Mallinckrodt Chemical Works | Composition containing spray dry particle of n-acetyl-p-aminophenol and manufacture |
US4562024A (en) * | 1982-07-06 | 1985-12-31 | Sterling Drug Inc. | Process for preparing granulate containing poorly compressible medicinally active matter |
AU574345B2 (en) * | 1982-07-06 | 1988-07-07 | Sterling Drug Inc. | Preparing compressed tablets by wet granulation and tablets therefrom |
US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
US4661521A (en) * | 1984-04-30 | 1987-04-28 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
US4631284A (en) * | 1984-11-19 | 1986-12-23 | Mallinckrodt, Inc. | Acetaminophen compositions containing low doses of chlorpheniramine maleate, method for preparing same and tablets formed therefrom |
US4757090A (en) * | 1986-07-14 | 1988-07-12 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
WO1989002266A1 (en) * | 1987-09-17 | 1989-03-23 | Mallinckrodt, Inc. | A free-flowing granular composition containing ibuprofen and a method for its preparation |
WO1994020086A1 (en) * | 1993-03-12 | 1994-09-15 | British Technology Group Limited | Pharmaceutical compositions comprising paracetamol and l-cysteine or a precursor thereof |
US9724302B2 (en) | 2010-04-09 | 2017-08-08 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US9730892B2 (en) | 2010-04-09 | 2017-08-15 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US9737482B2 (en) | 2010-04-09 | 2017-08-22 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US9737483B2 (en) | 2010-04-09 | 2017-08-22 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US9757336B2 (en) | 2010-04-09 | 2017-09-12 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US9808424B2 (en) | 2010-04-09 | 2017-11-07 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US10045941B2 (en) | 2010-04-09 | 2018-08-14 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
US10398648B2 (en) | 2010-04-09 | 2019-09-03 | Pacira Pharmaceuticals, Inc. | Method for formulating large diameter synthetic membrane vesicles |
Also Published As
Publication number | Publication date |
---|---|
FR2150903B1 (en) | 1975-10-17 |
DE2241960A1 (en) | 1973-03-15 |
FR2150903A1 (en) | 1973-04-13 |
DK131418B (en) | 1975-07-14 |
ZA725791B (en) | 1973-05-30 |
DK131418C (en) | 1975-12-01 |
DE2241960C2 (en) | 1982-02-04 |
CA988424A (en) | 1976-05-04 |
AU4584572A (en) | 1974-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |