DK0686044T3 - Hæmning af intimal hyperplasi under anvendelse af antistoffer mod PDGF-receptorer - Google Patents
Hæmning af intimal hyperplasi under anvendelse af antistoffer mod PDGF-receptorerInfo
- Publication number
- DK0686044T3 DK0686044T3 DK94909627T DK94909627T DK0686044T3 DK 0686044 T3 DK0686044 T3 DK 0686044T3 DK 94909627 T DK94909627 T DK 94909627T DK 94909627 T DK94909627 T DK 94909627T DK 0686044 T3 DK0686044 T3 DK 0686044T3
- Authority
- DK
- Denmark
- Prior art keywords
- intimal hyperplasia
- inhibition
- antibodies against
- pdgf
- receptor antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2350493A | 1993-02-25 | 1993-02-25 | |
PCT/US1994/001611 WO1994019016A1 (en) | 1993-02-25 | 1994-02-17 | Inhibition of intimal hyperplasia using antibodies to pdgf receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0686044T3 true DK0686044T3 (da) | 2000-10-09 |
Family
ID=21815476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94909627T DK0686044T3 (da) | 1993-02-25 | 1994-02-17 | Hæmning af intimal hyperplasi under anvendelse af antistoffer mod PDGF-receptorer |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0686044B1 (da) |
JP (1) | JP2944218B2 (da) |
AT (1) | ATE170402T1 (da) |
CA (1) | CA2156825C (da) |
DE (1) | DE69413009T2 (da) |
DK (1) | DK0686044T3 (da) |
ES (1) | ES2122248T3 (da) |
WO (1) | WO1994019016A1 (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7252929B2 (en) | 1989-02-09 | 2007-08-07 | United States Of America, As Represented By The Secretary, Dept Of Health & Human Services | Methods for identifying alpha PDGFR agonists and antagonists |
US6228600B1 (en) | 1992-07-20 | 2001-05-08 | The United States Of America As Represented By The Department Of Health And Human Services | Immunoassays for the alpha platelet-derived growth factor receptor |
US5976534A (en) * | 1993-02-25 | 1999-11-02 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF receptors and heparin |
US5882644A (en) * | 1996-03-22 | 1999-03-16 | Protein Design Labs, Inc. | Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof |
AU6497198A (en) * | 1997-02-14 | 1998-09-08 | Boehringer Mannheim Gmbh | Improved method for the reduction of neointima formation after angioplasty |
WO1999024059A1 (en) * | 1997-11-07 | 1999-05-20 | Massachusetts Institute Of Technology | Pdgf-mediated microvascular communication and methods of use thereof |
AU775590B2 (en) | 2000-01-25 | 2004-08-05 | Edwards Lifesciences Corporation | Delivery systems for treatment of restenosis and anastomotic intimal hyperplasia |
US6990848B2 (en) * | 2002-08-05 | 2006-01-31 | Trxoler Electronic Laboratories, Inc. | System and method for determining material properties of samples |
PL2100618T3 (pl) | 2005-06-17 | 2014-07-31 | Imclone Llc | Przeciwciało anty-PDGFR alfa do zastosowania w leczeniu przerzutowego raka kości |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2194760C2 (ru) * | 1991-12-02 | 2002-12-20 | Кор Терапьютикс, Инк. | Иммуноглобулиновый полипептид, его фрагмент, композиция, штамм гибридных культивируемых клеток, способ получения полипептида |
-
1994
- 1994-02-17 DE DE69413009T patent/DE69413009T2/de not_active Expired - Fee Related
- 1994-02-17 EP EP94909627A patent/EP0686044B1/en not_active Expired - Lifetime
- 1994-02-17 CA CA002156825A patent/CA2156825C/en not_active Expired - Fee Related
- 1994-02-17 ES ES94909627T patent/ES2122248T3/es not_active Expired - Lifetime
- 1994-02-17 WO PCT/US1994/001611 patent/WO1994019016A1/en active IP Right Grant
- 1994-02-17 DK DK94909627T patent/DK0686044T3/da active
- 1994-02-17 JP JP6519074A patent/JP2944218B2/ja not_active Expired - Fee Related
- 1994-02-17 AT AT94909627T patent/ATE170402T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0686044B1 (en) | 1998-09-02 |
JP2944218B2 (ja) | 1999-08-30 |
CA2156825C (en) | 2003-10-21 |
DE69413009D1 (de) | 1998-10-08 |
ATE170402T1 (de) | 1998-09-15 |
DE69413009T2 (de) | 1999-03-25 |
EP0686044A1 (en) | 1995-12-13 |
JPH08507063A (ja) | 1996-07-30 |
ES2122248T3 (es) | 1998-12-16 |
CA2156825A1 (en) | 1994-09-01 |
WO1994019016A1 (en) | 1994-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0801572T3 (da) | Sammensætning til inhibering af intimal hyperplasi ved anvendelse af PDGF-antagonister og heparin | |
DK0835115T3 (da) | 4-(2-(N-2-carboxamidoindo)aminoethyl)-benzensulfonamider eller -sulfonylurinstoffer som PDGF-antagonister | |
EA200200503A1 (ru) | Способ лечения ревматоидного артрита | |
DK0686044T3 (da) | Hæmning af intimal hyperplasi under anvendelse af antistoffer mod PDGF-receptorer | |
DK0673255T3 (da) | Monoklonale antistoffer, som specifikt binder til vaskulært tumorendotel, og anvendelser deraf | |
ATE254631T1 (de) | Pretargeting verfahren und mitteln | |
DE69133179T2 (de) | Katalytische antikörperkomponente | |
DK0580429T3 (da) | Anvendelse af kompetitive NMDA-receptorantagonister ved behandling af urininkontinens | |
DK0831807T3 (da) | Anvendelse af Brefeldin A og derivater deraf til fremstilling af lægemidler til behandling af hyperplasia og beslægtede lidelser | |
BR9913533A (pt) | Processos para tratar hipertensão e composições para uso nos mesmos | |
DE69915977D1 (de) | Neuartige Heparin bindende Peptide | |
WO2003010201A3 (en) | Blood group antigen fusion polypeptides and methods of use thereof | |
ES2196150T3 (es) | Induccion de tolerancia inmunologica por el uso de anticuerpos anti-cd4 que no inducen deplecion. | |
HK1010395A1 (en) | Binding domains from plasmodium vivax and plasmodium falciparum erythrocyte binding proteins. | |
DK0606391T3 (da) | Inhibering af karforsnævring under anvendelse af anti-PADGEM-antistoffer | |
ES2054484T3 (es) | Composiciones farmaceuticas que contienen complejos de antigeno-anticuerpo, asi como la utilizacion de las mismas. | |
FI20095269A (fi) | Lymfosyyttien sitoutumiseen vaikuttava ihmisen endoteelisolun molekyyli | |
DE69123871D1 (de) | Anti-Oncostatin-M monoklonale Antikörper | |
FR2697154B1 (fr) | Perfectionnement au composant fémoral des prothèse du genou. | |
MX9102586A (es) | Composicion de resina poli acetalica. composicion de resina poliacetalica. |