ES2054484T3 - Composiciones farmaceuticas que contienen complejos de antigeno-anticuerpo, asi como la utilizacion de las mismas. - Google Patents

Composiciones farmaceuticas que contienen complejos de antigeno-anticuerpo, asi como la utilizacion de las mismas.

Info

Publication number
ES2054484T3
ES2054484T3 ES91900689T ES91900689T ES2054484T3 ES 2054484 T3 ES2054484 T3 ES 2054484T3 ES 91900689 T ES91900689 T ES 91900689T ES 91900689 T ES91900689 T ES 91900689T ES 2054484 T3 ES2054484 T3 ES 2054484T3
Authority
ES
Spain
Prior art keywords
antigen
treatment
well
same
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91900689T
Other languages
English (en)
Inventor
Jean-Marie Saint-Remy
Philippe Lebrun
Serge Lebeque
Pierre Lucien Masson
Marc Jacquemin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INT INST CELLULAR MOLECUL PATH
International Institute of Cellular and Molecular Pathology
Original Assignee
INT INST CELLULAR MOLECUL PATH
International Institute of Cellular and Molecular Pathology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INT INST CELLULAR MOLECUL PATH, International Institute of Cellular and Molecular Pathology filed Critical INT INST CELLULAR MOLECUL PATH
Application granted granted Critical
Publication of ES2054484T3 publication Critical patent/ES2054484T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6056—Antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Rehabilitation Therapy (AREA)
  • Diabetes (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE PRESENTA UN COMPUESTO FARMACEUTICO ADECUADO PARA SU ADMINISTRACIONA LOS SERES HUMANOS PARA LA PREVENCION O TRATAMIENTO DE ENFERMEDADES INMUNOLOGICAS, EL COMPUESTO INCLUYE: UN COMPLEJO INMUNE DE UN ANTIGENO Y UN ANTICUERPO PURIFICADO ESPECIFICO PARA EL MISMO, EL ANTIGENO ESTA SELECCIONADO ENTRE UN GRUPO QUE CONSTA DE LOS ANTIGENOS QUE PROVOCAN REACCIONES INMUNOLOGICAS PATOGENAS EN ENFERMEDADES AUTOINMUNES Y RECHAZO DE TRANSPLANTES, Y EL ANTIGENO Y EL ANTICUERPO ESTAN PRESENTES EN UNA PROPORCION MEDIANTE LA CUAL EL ANTICUERPO BLOQUEA ESENCIALMENTE TODOS LOS ENLACES DEL ANTIGENO; TAMBIEN SE PRESENTA UN PORTADOR O DILUYENTES FARMACOLOGICAMENTE ACEPTABLE. LA INVENCION TAMBIEN SUMINISTRA UN METODO PARA LA ADMINISTRACION DEL COMPUESTO PARA EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES Y EL TRATAMIENTO O PREVENCION DE RECHAZOS EN TRANSPLANTES.
ES91900689T 1990-01-03 1990-12-31 Composiciones farmaceuticas que contienen complejos de antigeno-anticuerpo, asi como la utilizacion de las mismas. Expired - Lifetime ES2054484T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46051490A 1990-01-03 1990-01-03

Publications (1)

Publication Number Publication Date
ES2054484T3 true ES2054484T3 (es) 1994-08-01

Family

ID=23829022

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91900689T Expired - Lifetime ES2054484T3 (es) 1990-01-03 1990-12-31 Composiciones farmaceuticas que contienen complejos de antigeno-anticuerpo, asi como la utilizacion de las mismas.

Country Status (15)

Country Link
US (1) US7122380B1 (es)
EP (1) EP0508993B1 (es)
JP (1) JPH03227942A (es)
AT (1) ATE103495T1 (es)
AU (1) AU644400B2 (es)
CA (1) CA2015515C (es)
DE (1) DE69007799T2 (es)
DK (1) DK0508993T3 (es)
ES (1) ES2054484T3 (es)
HU (1) HUT62486A (es)
IE (1) IE65399B1 (es)
NO (1) NO922621L (es)
PL (1) PL288597A1 (es)
PT (1) PT96409A (es)
WO (1) WO1991009619A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5620686A (en) * 1990-09-28 1997-04-15 British Technology Group Limited Antigen-antibody conjugates
DE69123256T2 (de) * 1990-09-28 1997-06-12 British Tech Group Antigen-antikörperkonjugaten
AU696560B2 (en) * 1993-03-19 1998-09-10 Fred D. Finkelman Pharmaceutical compositions comprising a ligand complexed with a soluble receptor
FR2728264B1 (fr) * 1994-12-16 1997-01-31 Rhone Poulenc Rorer Sa Purification d'adn par formation de triple helice avec un oligonucleotide immobilise
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
AU1267501A (en) * 1999-09-07 2001-04-10 Bioserv Ag Novel autogenous vaccines used to obtain an immune tolerance
CA2526950C (en) 2002-05-27 2012-06-26 Leif Hakansson Method for determining immune system affecting compounds
JP2007502305A (ja) * 2003-08-15 2007-02-08 ザ ガバナーズ オブ ザ ユニバーシティー オブ カルガリー 哺乳動物の抗原特異的抗体のレベルを操作するための組成物および方法
AU2011218660B2 (en) * 2003-08-15 2011-12-15 The Governors Of The University Of Calgary Compositions and methods for manipulating levels of antigen-specific antibodies in a mammal
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
US8110347B2 (en) 2005-04-15 2012-02-07 Canimguide Therapeutics Ab Diagnostic method for detecting cancer by measuring amount of cytokine like IL-6
GB2440528A (en) * 2006-07-27 2008-02-06 Ist Superiore Sanita Antigen-antibody complexes
ES2747363T3 (es) 2007-05-08 2020-03-10 Canimguide Therapeutics Ab Estructuras inmunorreguladoras de proteínas que se encuentran normalmente
WO2017218677A2 (en) * 2016-06-14 2017-12-21 Arizona Board Of Regents On Behalf Of Arizona State University Identification and medical applications of anti-citrullinated-protein antibodies in rheumatoid arthritis

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140679A (en) 1976-10-12 1979-02-20 Research Corporation Antigen-protein complex for blocking allergic reactions
US4234569A (en) 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
DE2846412A1 (de) 1978-10-25 1980-05-08 Behringwerke Ag Mittel zur behandlung allergischer reaktionen
US4521405A (en) 1982-05-17 1985-06-04 John McMichael Methods and materials for treatment of disease states involving immunological factors
US4545986A (en) 1982-06-22 1985-10-08 Research Corporation Timothy grass antigen specific anti-idiotypic antibodies
US4564600A (en) 1982-10-26 1986-01-14 Majid Ali Allergens and antibodies from allergen extracts and pooled serum
US4702907A (en) 1983-08-09 1987-10-27 Cornell Research Foundation, Inc. Process for inducing selective immunosuppression of antibodies
US4681760A (en) 1985-04-17 1987-07-21 The Board Of Trustees Of The Leland Stanford Junior University Method of conferring immunotolerance to a specific antigen
CA1282069C (en) 1985-09-12 1991-03-26 Damon L. Meyer Antibody complexes of hapten-modified diagnostic or therapeutic agents
US4714759A (en) 1985-12-02 1987-12-22 Whitaker Jr Robert B Immunotoxin therapy of allergy
GB8608068D0 (en) 1986-04-02 1986-05-08 Cobbold S P Monoclonal antibodies
GB8610983D0 (en) 1986-05-06 1986-06-11 Connaught Lab Enhancement of antigen immunogenicity
EP0411017B1 (en) * 1988-04-04 1996-03-06 POTEMPA, Lawrence A. Binding of immune complexes by modified forms of c-reactive protein

Also Published As

Publication number Publication date
HU9202214D0 (en) 1992-10-28
HUT62486A (en) 1993-05-28
AU644400B2 (en) 1993-12-09
AU6962691A (en) 1991-07-24
NO922621D0 (no) 1992-07-02
EP0508993A1 (en) 1992-10-21
CA2015515A1 (en) 1991-07-03
EP0508993B1 (en) 1994-03-30
PT96409A (pt) 1991-10-15
ATE103495T1 (de) 1994-04-15
US7122380B1 (en) 2006-10-17
PL288597A1 (en) 1991-08-12
IE65399B1 (en) 1995-10-18
JPH03227942A (ja) 1991-10-08
DE69007799T2 (de) 1994-10-20
NO922621L (no) 1992-09-02
DK0508993T3 (da) 1994-05-09
IE904693A1 (en) 1991-07-17
CA2015515C (en) 1999-12-07
DE69007799D1 (de) 1994-05-05
WO1991009619A1 (en) 1991-07-11

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