DK0680333T3 - Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase - Google Patents

Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase

Info

Publication number
DK0680333T3
DK0680333T3 DK94906142T DK94906142T DK0680333T3 DK 0680333 T3 DK0680333 T3 DK 0680333T3 DK 94906142 T DK94906142 T DK 94906142T DK 94906142 T DK94906142 T DK 94906142T DK 0680333 T3 DK0680333 T3 DK 0680333T3
Authority
DK
Denmark
Prior art keywords
prevention
treatment
cytomegalovirus
aminopeptidase
aminopeptidases
Prior art date
Application number
DK94906142T
Other languages
English (en)
Inventor
John A Zaia
Terrence Giugni
Erna Miller
Cecilia Siderberg
Original Assignee
Erna Miller
Cecilia Siderberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erna Miller, Cecilia Siderberg filed Critical Erna Miller
Application granted granted Critical
Publication of DK0680333T3 publication Critical patent/DK0680333T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Anesthesiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK94906142T 1993-01-21 1994-01-21 Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase DK0680333T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US698293A 1993-01-21 1993-01-21
US9966493A 1993-07-30 1993-07-30
PCT/EP1994/000188 WO1994016724A1 (en) 1993-01-21 1994-01-21 Prevention and treatment of cytomegalovirus using aminopeptidase

Publications (1)

Publication Number Publication Date
DK0680333T3 true DK0680333T3 (da) 2000-01-03

Family

ID=26676317

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94906142T DK0680333T3 (da) 1993-01-21 1994-01-21 Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase

Country Status (11)

Country Link
US (1) US6511662B1 (da)
EP (1) EP0680333B1 (da)
JP (1) JPH08506106A (da)
AT (1) ATE179613T1 (da)
AU (1) AU681115B2 (da)
CA (1) CA2154346A1 (da)
DE (1) DE69418307T2 (da)
DK (1) DK0680333T3 (da)
ES (1) ES2131188T3 (da)
GR (1) GR3030462T3 (da)
WO (1) WO1994016724A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002527489A (ja) * 1998-10-22 2002-08-27 キュラゲン コーポレイション 腎疾患および関連疾患に対する予想および治療的遺伝子およびタンパク質
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0803076D0 (en) * 2008-02-20 2008-03-26 Univ Ghent Mucosal Membrane Receptor and uses thereof
MX343490B (es) 2008-07-16 2016-11-08 Inst For Res In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos.

Also Published As

Publication number Publication date
EP0680333A1 (en) 1995-11-08
GR3030462T3 (en) 1999-10-29
ES2131188T3 (es) 1999-07-16
JPH08506106A (ja) 1996-07-02
ATE179613T1 (de) 1999-05-15
DE69418307D1 (de) 1999-06-10
WO1994016724A1 (en) 1994-08-04
CA2154346A1 (en) 1994-08-04
DE69418307T2 (de) 1999-11-04
EP0680333B1 (en) 1999-05-06
US6511662B1 (en) 2003-01-28
AU5999194A (en) 1994-08-15
AU681115B2 (en) 1997-08-21

Similar Documents

Publication Publication Date Title
BG100455A (en) Hiv protease inhibitors
DK57391A (da) Hiv proteiner og peptider til anvendelse ved diagnosticering, profylakse og behandling af aids
NO994639D0 (no) Antimikrobiell forebyggelse og behandling av humant immunsviktvirus og andre infeksiöse sykdommer
NO905428D0 (no) Fremgangsmaate for fremstilling av hiv-proteaseinhibitorerfor behandling av aids.
ATE298741T1 (de) Polyaromatische verbindungen zur behandlung von herpes-infektionen
NO20020571L (no) Peptider som blokkerer infeksjonsevnen, og fremgangsmåter for anvendelse av disse
SE8602981D0 (sv) Novel medicinal use
DE69518840D1 (en) N-(3-amino-2-hydroxybutyl)sulfonamid-derivate as hiv-protease-inhibitoren
DE69420229T2 (de) Pharmazeutische Zusammensetzung zur Behandlung von AIDS
DK0680333T3 (da) Forebyggelse og behandling af cytomegalovirus ved hjælp af aminopeptidase
EP0821965A3 (de) Verwendung von (Meth)arcylsäure-Maleinsäure-Copolymeren zur Verbesserung der Permeabilität der Schleimhaut
DE69805305D1 (de) Verwendung von phanquinon zur behandlung von alzheimer's krankheit
KR950700761A (ko) 사람 면역결핍 바이러스(HIV) 감염의 예방 및 치료를 위한 재조합 사람 HIV-중화 모노클로날 항체(Recombinant human HIV-neutralizing monoclonal antibodies for prevention and treatment of HIV infection)
NO931246D0 (no) Sammensetninger for behandling av infeksjon og sykdom foraarsaket av hepatites b virus (hbv)
BG102404A (en) The application of flupirtin for the prevention and treatment of diseases related to impairement of the haematopoeic cellular system
DE69718500D1 (de) (-)-enantiomere von cis-3,4-chromanderivaten zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen
UA41338C2 (uk) Спосіб інгібування ретровірусної інфекції, яка викликана вірусом імунодефіциту людини (віл), спосіб інгібування вірусу імунодефіциту людини (віл)
DE69717844T2 (de) Neue cis-3,4-chromanderivate zur vorbeugung oder behandlung von oestrogenbezogenen krankheiten oder syndromen
WO1997026880A3 (en) Use of a combination of delavirdine and one or more protease inhibitors in hiv-1 infected patients
AU9495098A (en) Methods for use of interleukin 4 (il-4) to treat human immunodeficiency virus infection
DE3874606D1 (de) Behandlung von viraler infektion.
EP0316592A3 (en) 3'-fluoro-2',3'-dideoxyuridine, and its therapeutic application
AU3593095A (en) Method of treatment of human immunodeficiency virus (hiv) infection
AU6447690A (en) Method of administering soluble t4 for treatment of human immunodeficiency virus infection
NO982151D0 (no) Hemoregulatoriske forbindelser