DE69418307D1 - Verhütung und behandlung von zytomegalovirus mittels aminopeptidase - Google Patents

Verhütung und behandlung von zytomegalovirus mittels aminopeptidase

Info

Publication number
DE69418307D1
DE69418307D1 DE69418307T DE69418307T DE69418307D1 DE 69418307 D1 DE69418307 D1 DE 69418307D1 DE 69418307 T DE69418307 T DE 69418307T DE 69418307 T DE69418307 T DE 69418307T DE 69418307 D1 DE69418307 D1 DE 69418307D1
Authority
DE
Germany
Prior art keywords
prevention
treatment
zytomegalovirus
aminopeptidase
aminopeptidases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69418307T
Other languages
English (en)
Other versions
DE69418307T2 (de
Inventor
John A Zaia
Terrence Giugni
Erna Moeller
Cecilia Soederberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MOELLER ERNA SALTSJOBADEN SE
SOEDERBERG CECILIA HARGERSTEN SE
Original Assignee
MOELLER ERNA SALTSJOBADEN SE
SOEDERBERG CECILIA HARGERSTEN SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MOELLER ERNA SALTSJOBADEN SE, SOEDERBERG CECILIA HARGERSTEN SE filed Critical MOELLER ERNA SALTSJOBADEN SE
Publication of DE69418307D1 publication Critical patent/DE69418307D1/de
Application granted granted Critical
Publication of DE69418307T2 publication Critical patent/DE69418307T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Anesthesiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69418307T 1993-01-21 1994-01-21 Verhütung und behandlung von zytomegalovirus mittels aminopeptidase Expired - Fee Related DE69418307T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US698293A 1993-01-21 1993-01-21
US9966493A 1993-07-30 1993-07-30
PCT/EP1994/000188 WO1994016724A1 (en) 1993-01-21 1994-01-21 Prevention and treatment of cytomegalovirus using aminopeptidase

Publications (2)

Publication Number Publication Date
DE69418307D1 true DE69418307D1 (de) 1999-06-10
DE69418307T2 DE69418307T2 (de) 1999-11-04

Family

ID=26676317

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69418307T Expired - Fee Related DE69418307T2 (de) 1993-01-21 1994-01-21 Verhütung und behandlung von zytomegalovirus mittels aminopeptidase

Country Status (11)

Country Link
US (1) US6511662B1 (de)
EP (1) EP0680333B1 (de)
JP (1) JPH08506106A (de)
AT (1) ATE179613T1 (de)
AU (1) AU681115B2 (de)
CA (1) CA2154346A1 (de)
DE (1) DE69418307T2 (de)
DK (1) DK0680333T3 (de)
ES (1) ES2131188T3 (de)
GR (1) GR3030462T3 (de)
WO (1) WO1994016724A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2347625A1 (en) * 1998-10-22 2000-04-27 Richard A. Shimkets Genes and proteins predictive and therapeutic for renal disease and associated disorders
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0803076D0 (en) * 2008-02-20 2008-03-26 Univ Ghent Mucosal Membrane Receptor and uses thereof
PE20141434A1 (es) 2008-07-16 2014-10-22 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano

Also Published As

Publication number Publication date
GR3030462T3 (en) 1999-10-29
JPH08506106A (ja) 1996-07-02
CA2154346A1 (en) 1994-08-04
WO1994016724A1 (en) 1994-08-04
ATE179613T1 (de) 1999-05-15
AU5999194A (en) 1994-08-15
DK0680333T3 (da) 2000-01-03
DE69418307T2 (de) 1999-11-04
EP0680333A1 (de) 1995-11-08
EP0680333B1 (de) 1999-05-06
AU681115B2 (en) 1997-08-21
US6511662B1 (en) 2003-01-28
ES2131188T3 (es) 1999-07-16

Similar Documents

Publication Publication Date Title
ATE230757T1 (de) Verabreichung von peptidylheterocyclen zur behandlung von thrombin in zusammenhang stehenden krankheiten
MY138860A (en) Hiv protease inhibitors.
ATE277612T1 (de) Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen
DE3588023D1 (de) Mittel zur Behandlung von Herzerkrankungen.
DE69426690D1 (de) Behandlung von atrophischer Haut und Vagina
ATE263761T1 (de) 5,6-dihydropyronderivate als proteaseinhibitoren und antiviralmittel
DE3750934D1 (de) Behandlung von nicht-Akne-entzündlichen und -infektiösen Hautkrankheiten.
DE69518840D1 (en) N-(3-amino-2-hydroxybutyl)sulfonamid-derivate as hiv-protease-inhibitoren
ATE439833T1 (de) Pharmazeutische zubereitung enthaltend ein catechin, ascorbinsäure, prolin und lysin zur behandlung von neoplastischen krankheiten
DE69620691D1 (de) Therapeutisches Mittel zur Behandlung der Hypercholesterinämie
DE60035693D1 (de) Zusammensetzung und verfahren zur behandlung von immunverwandten krankheiten
MD960172A (en) 5,6-dihydropyrone derivatives as proteaze inhibitors and antiviral agents
ATE217191T1 (de) Verwendung von phanquinon zur behandlung von alzheimer's krankheit
DE69418307D1 (de) Verhütung und behandlung von zytomegalovirus mittels aminopeptidase
DE69420229D1 (de) Pharmazeutische Zusammensetzung zur Behandlung von AIDS
ATE151774T1 (de) Cyclopentanperhydrophenanthren-17-beta-(3-furyl - 3-derivate und pharmazeutische präparate davon, zur behandlung von kardiovaskulär-erkrankungen
BG102404A (en) The application of flupirtin for the prevention and treatment of diseases related to impairement of the haematopoeic cellular system
DE69718500D1 (de) (-)-enantiomere von cis-3,4-chromanderivaten zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen
WO1997026880A3 (en) Use of a combination of delavirdine and one or more protease inhibitors in hiv-1 infected patients
HUP0100937A2 (hu) Többszörösen elágazó peptidkonstrukciókat tartalmazó liposzómák és alkalmazásuk humán immundeficiencia vírus ellen
ATE229343T1 (de) Kombination von temozolomide und alpha-interferon zur behandlung von fortgeschrittenem krebs
ATE203680T1 (de) Konjugat zur behandlung von entzündungserkrankungen
ATE255417T1 (de) Verwendung von bradykinin-antagonisten zur behandlung von viruserkrankungen
DE3883754D1 (de) Mittel zur prophylaxe und behandlung von viralen infektionskrankheiten.
NO982151D0 (no) Hemoregulatoriske forbindelser

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee