DK0674521T3 - Fremgangsmåde til behandling af kronisk prostatitis med 17beta-N-tertbutylcarbamoyl-4-aza-5a-andost-1-en-3-on - Google Patents

Fremgangsmåde til behandling af kronisk prostatitis med 17beta-N-tertbutylcarbamoyl-4-aza-5a-andost-1-en-3-on

Info

Publication number
DK0674521T3
DK0674521T3 DK94901556T DK94901556T DK0674521T3 DK 0674521 T3 DK0674521 T3 DK 0674521T3 DK 94901556 T DK94901556 T DK 94901556T DK 94901556 T DK94901556 T DK 94901556T DK 0674521 T3 DK0674521 T3 DK 0674521T3
Authority
DK
Denmark
Prior art keywords
aza
pct
chronic prostatitis
andost
tertbutylcarbamoyl
Prior art date
Application number
DK94901556T
Other languages
Danish (da)
English (en)
Inventor
Glenn J Gormley
Elizabeth Stoner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0674521T3 publication Critical patent/DK0674521T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK94901556T 1992-12-18 1993-11-18 Fremgangsmåde til behandling af kronisk prostatitis med 17beta-N-tertbutylcarbamoyl-4-aza-5a-andost-1-en-3-on DK0674521T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99298592A 1992-12-18 1992-12-18
PCT/US1993/011155 WO1994014452A1 (en) 1992-12-18 1993-11-18 METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17β-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES

Publications (1)

Publication Number Publication Date
DK0674521T3 true DK0674521T3 (da) 2001-09-24

Family

ID=25538974

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94901556T DK0674521T3 (da) 1992-12-18 1993-11-18 Fremgangsmåde til behandling af kronisk prostatitis med 17beta-N-tertbutylcarbamoyl-4-aza-5a-andost-1-en-3-on

Country Status (17)

Country Link
US (1) US5629318A (fi)
EP (1) EP0674521B1 (fi)
JP (1) JPH08504813A (fi)
AT (1) ATE203162T1 (fi)
AU (1) AU691164B2 (fi)
CA (1) CA2151239A1 (fi)
CZ (1) CZ285379B6 (fi)
DE (1) DE69330465T2 (fi)
DK (1) DK0674521T3 (fi)
ES (1) ES2158887T3 (fi)
FI (1) FI953002A0 (fi)
GR (1) GR3036241T3 (fi)
HU (1) HU220064B (fi)
NO (1) NO308829B1 (fi)
NZ (1) NZ258435A (fi)
PT (1) PT674521E (fi)
WO (1) WO1994014452A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3993899A (en) * 1998-05-18 1999-12-06 Merck & Co., Inc. Method for treating or preventing chronic nonbacterial prostatitis and prostatodynia
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
US7101847B2 (en) * 2002-10-11 2006-09-05 Milkhaus Laboratory, Inc. Method of treating chronic pelvic pain syndrome by administration of chorionic gonadotropin
US7446110B2 (en) * 2003-09-10 2008-11-04 Merck & Co., Inc. 17-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators
AU2004288196B2 (en) * 2003-10-31 2009-11-26 Merck Sharp & Dohme Corp. 21-heterocyclic-4-azasteroid derivatives as androgen receptor modulators
US20080268463A1 (en) * 2007-03-07 2008-10-30 Children's Medical Center Corporation Methods for Prognosis and Diagnosis of Chronic Prostatitis/Pelvic Pain Syndrome and Interstitial Cystitis
RU2525182C1 (ru) * 2013-02-28 2014-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) Способ лечения больных хроническим простатитом с парциальным андрогенодефицитом
CN104161739B (zh) * 2014-08-15 2017-09-19 武汉人福药业有限责任公司 非那雄胺胶囊及其制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2227876A (en) * 1937-10-16 1941-01-07 Firm Of N V Organon Steroid derivatives with nuclear substituted nitrogen
US3285918A (en) * 1962-04-18 1966-11-15 Norman J Doorenbos 1', 4', 5', 6'-tetrahydropyrimidino[a-4, 3]-4-aza-5-cholestene
US3239417A (en) * 1962-12-07 1966-03-08 Smith Kline French Lab Methods and compositions for inhibiting sterol biosynthesis
US3264301A (en) * 1963-08-22 1966-08-02 Norman J Doorenbos Substituted-4-azasteroids
FR1465544A (fr) * 1965-11-29 1967-01-13 Roussel Uclaf Dérivés stéroïdes aromatiques substitués par un atome d'azote endocyclique et procédé de préparation
US4377584A (en) * 1978-04-13 1983-03-22 Merck & Co., Inc. 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
US4220775A (en) * 1979-03-15 1980-09-02 Merck & Co., Inc. Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors
US5049562A (en) * 1984-02-27 1991-09-17 Merck & Co., Inc. 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors
US4859681A (en) * 1984-02-27 1989-08-22 Merck & Co., Inc. 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
DE3888378T2 (de) * 1987-04-03 1994-09-29 Merck & Co Inc Behandlung von Prostatacarcinoma mit 17-beta-n-monosubstituierten-Carbamoyl-4-aza-5-alpha-Androst-1-en-3-onen.
US4946688A (en) * 1988-07-05 1990-08-07 Fahim Mostafa S Intraprostatic injection of zinc ions for treatment of inflammatory conditions and benign and malignant tumors of the prostate
DK627289D0 (da) * 1989-12-12 1989-12-12 Per C Oden Anvendelse af bicyclononanderivater
US5175155A (en) * 1991-10-07 1992-12-29 Sterling Winthrop Inc. Win 49596-finasteride method of use and compositions
WO1993023420A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. NEW 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS
AU4251993A (en) * 1992-05-20 1993-12-13 Merck & Co., Inc. Substituted 4-aza-5A-androstan-ones as 5A-reductase inhibitors
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
US5693810A (en) * 1992-10-06 1997-12-02 Merck & Co., Inc. 17 β-carboxanilides of 4-aza-5α-androstan-3-ones as 5α-reductase inhibitors

Also Published As

Publication number Publication date
AU691164B2 (en) 1998-05-14
ES2158887T3 (es) 2001-09-16
CA2151239A1 (en) 1994-07-07
DE69330465T2 (de) 2002-04-25
AU5610594A (en) 1994-07-19
CZ285379B6 (cs) 1999-07-14
DE69330465D1 (de) 2001-08-23
NZ258435A (en) 1997-05-26
WO1994014452A1 (en) 1994-07-07
NO308829B1 (no) 2000-11-06
NO952427L (no) 1995-06-16
HU9501777D0 (en) 1995-08-28
NO952427D0 (no) 1995-06-16
HU220064B (hu) 2001-10-28
CZ157795A3 (en) 1995-11-15
EP0674521A4 (en) 1998-02-04
EP0674521B1 (en) 2001-07-18
HUT73231A (en) 1996-07-29
US5629318A (en) 1997-05-13
EP0674521A1 (en) 1995-10-04
JPH08504813A (ja) 1996-05-28
PT674521E (pt) 2001-10-31
FI953002A (fi) 1995-06-16
GR3036241T3 (en) 2001-10-31
FI953002A0 (fi) 1995-06-16
ATE203162T1 (de) 2001-08-15

Similar Documents

Publication Publication Date Title
ATE307119T1 (de) Bicyclische protein-farnesyl-transferase inhibitoren
DE69815090D1 (de) Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen
NZ332762A (en) Isobutylgaba and its derivatives for the treatment of pain
FI971967A (fi) Dioksomorfoliinien käyttö sisäloisten torjuntaan, uusia dioksomorfiineja ja menetelmä niiden valmistamiseksi
FI970149A (fi) Tiatsoli- ja tiadiatsoliyhdisteiden käyttö D3-reseptoriligandeina
BR9307695A (pt) Novos antioxidantes fenólicos lìquidos
NO20003398L (no) Substituerte 2-benzylamino-2-fenyl-acetamid-forbindelser
DK0674521T3 (da) Fremgangsmåde til behandling af kronisk prostatitis med 17beta-N-tertbutylcarbamoyl-4-aza-5a-andost-1-en-3-on
ATE168105T1 (de) Melamine derivate zur verwendung in der behandlung von krebs
DE69623767T2 (de) Verwendung von pyrrolidinderivaten zur behandlung des alkoholismus
BR9906803A (pt) Processo para tratamento de copd
NO990436L (no) FremgangsmÕte for behandling av bipolar forstyrrelse
DK0971714T3 (da) Metode til anvendelse af cyklooxygenase-2-inhibitorer til behandling og forebyggelse af demens
DE69329994T2 (de) Arylalkoxyphenoxyimidazolinverbindungen
ATE206127T1 (de) Inhibitoren retroviraler proteasen