DK0673422T3 - Celler, der er modificeret med hensyn til katabolismen af betain, fremstilling og anvendelser, navnlig til produktion af metabolitter eller enzymer - Google Patents

Celler, der er modificeret med hensyn til katabolismen af betain, fremstilling og anvendelser, navnlig til produktion af metabolitter eller enzymer

Info

Publication number
DK0673422T3
DK0673422T3 DK94901994T DK94901994T DK0673422T3 DK 0673422 T3 DK0673422 T3 DK 0673422T3 DK 94901994 T DK94901994 T DK 94901994T DK 94901994 T DK94901994 T DK 94901994T DK 0673422 T3 DK0673422 T3 DK 0673422T3
Authority
DK
Denmark
Prior art keywords
enzymes
catabolism
betaine
metabolites
manufacture
Prior art date
Application number
DK94901994T
Other languages
English (en)
Inventor
Beatrice Cameron
Joel Crouzet
Original Assignee
Rhone Poulenc Biochimie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0673422(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Biochimie filed Critical Rhone Poulenc Biochimie
Application granted granted Critical
Publication of DK0673422T3 publication Critical patent/DK0673422T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK94901994T 1992-12-09 1993-12-07 Celler, der er modificeret med hensyn til katabolismen af betain, fremstilling og anvendelser, navnlig til produktion af metabolitter eller enzymer DK0673422T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214814A FR2698879B1 (fr) 1992-12-09 1992-12-09 gellules modifiées au niveau du catabolisme de la bétaïne, préparation et utilisations, notamment pour la production de métabolites ou d'enzymes.

Publications (1)

Publication Number Publication Date
DK0673422T3 true DK0673422T3 (da) 2006-05-15

Family

ID=9436376

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94901994T DK0673422T3 (da) 1992-12-09 1993-12-07 Celler, der er modificeret med hensyn til katabolismen af betain, fremstilling og anvendelser, navnlig til produktion af metabolitter eller enzymer

Country Status (10)

Country Link
US (2) US5691163A (da)
EP (1) EP0673422B1 (da)
JP (1) JP3488924B2 (da)
AT (1) ATE315091T1 (da)
CA (1) CA2151123C (da)
DE (1) DE69333962T2 (da)
DK (1) DK0673422T3 (da)
ES (1) ES2255052T3 (da)
FR (1) FR2698879B1 (da)
WO (1) WO1994013813A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0966521A1 (en) * 1996-09-13 1999-12-29 Novo Nordisk Biotech, Inc. Cells having dna insertion mutations which produce altered amounts of a polypeptide
WO2000011142A2 (en) * 1998-08-20 2000-03-02 Danisco Finland Oy Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof
BR0314681A (pt) * 2002-09-27 2005-08-02 Dsm Ip Assets Bv Gene ativador da transcrição para genes envolvidos na sìntese da cobalamina
EP2049677B1 (en) * 2006-08-10 2011-07-20 Merck Patent GmbH Method for isolating cells
BR112012025047A2 (pt) 2010-03-31 2016-06-21 Stabilitech Ltd formulações líquidas estabilizadas
ES2543795T3 (es) 2010-03-31 2015-08-21 Stabilitech Ltd. Estabilización de partículas virales
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
CN104345851A (zh) * 2013-07-24 2015-02-11 鸿富锦精密电子(天津)有限公司 电源电路
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55148084A (en) * 1979-05-08 1980-11-18 Mitsubishi Gas Chem Co Inc Incubation of microoranism
JPS62181791A (ja) * 1986-02-04 1987-08-10 Ajinomoto Co Inc 発酵法によるｌ−アミノ酸又は５′−イノシン酸の製造法
FR2657622B1 (fr) 1990-01-31 1994-11-25 Rhone Poulenc Sante Polypeptides impliques dans la biosynthese des cobalamines et/ou des cobamides, sequences d'adn codant pour ces polypeptides, procede de preparation, et leur utilisation.
RU2099418C1 (ru) * 1991-11-21 1997-12-20 Лонца Аг Фрагмент днк, обеспечивающий использование бетаина, рекомбинантная плазмидная днк с фрагментом днк, обеспечивающим использование бетаина, штамм бактерий rhizobium/agrobacterium, предназначенный для стабильного хранения плазмиды с фрагментом днк, способ получения штамма бактерий

Also Published As

Publication number Publication date
EP0673422B1 (fr) 2006-01-04
DE69333962T2 (de) 2006-08-24
USRE38331E1 (en) 2003-11-25
CA2151123C (fr) 2007-01-30
ATE315091T1 (de) 2006-02-15
CA2151123A1 (fr) 1994-06-23
WO1994013813A1 (fr) 1994-06-23
FR2698879B1 (fr) 1995-01-13
US5691163A (en) 1997-11-25
JPH08505286A (ja) 1996-06-11
DE69333962D1 (de) 2006-03-30
FR2698879A1 (fr) 1994-06-10
EP0673422A1 (fr) 1995-09-27
ES2255052T3 (es) 2006-06-16
JP3488924B2 (ja) 2004-01-19

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