DK0671904T3 - Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner - Google Patents

Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner

Info

Publication number
DK0671904T3
DK0671904T3 DK93911272T DK93911272T DK0671904T3 DK 0671904 T3 DK0671904 T3 DK 0671904T3 DK 93911272 T DK93911272 T DK 93911272T DK 93911272 T DK93911272 T DK 93911272T DK 0671904 T3 DK0671904 T3 DK 0671904T3
Authority
DK
Denmark
Prior art keywords
drug resistant
use against
against drug
formulation
resistant infections
Prior art date
Application number
DK93911272T
Other languages
Danish (da)
English (en)
Inventor
Evan M Hersh
Eskild A Petersen
Richard T Proffitt
Kevin R Bracken
Su-Ming Chiang
Original Assignee
Nexstar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexstar Pharmaceuticals Inc filed Critical Nexstar Pharmaceuticals Inc
Application granted granted Critical
Publication of DK0671904T3 publication Critical patent/DK0671904T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
DK93911272T 1992-12-02 1993-05-11 Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner DK0671904T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1992/010591 WO1994012155A1 (en) 1992-12-02 1992-12-02 Antibiotic formulation and process
PCT/US1993/004501 WO1994012156A1 (en) 1992-12-02 1993-05-11 Antibiotic formulation and use for drug resistant infections

Publications (1)

Publication Number Publication Date
DK0671904T3 true DK0671904T3 (da) 1999-12-06

Family

ID=22231603

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93911272T DK0671904T3 (da) 1992-12-02 1993-05-11 Antibiotisk præparat og anvendelse mod lægemiddelresistente infektioner

Country Status (11)

Country Link
US (1) US5756121A (ja)
EP (1) EP0671904B1 (ja)
JP (2) JP4084846B2 (ja)
AT (1) ATE183082T1 (ja)
AU (2) AU3244393A (ja)
CA (1) CA2150832C (ja)
DE (1) DE69326017T2 (ja)
DK (1) DK0671904T3 (ja)
ES (1) ES2134846T3 (ja)
GR (1) GR3031548T3 (ja)
WO (2) WO1994012155A1 (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958449A (en) 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
US6146890A (en) * 1994-07-03 2000-11-14 Danon; David Method and system for cultivating macrophages
US5662929A (en) * 1994-12-23 1997-09-02 Universite De Montreal Therapeutic liposomal formulation
US6726925B1 (en) * 1998-06-18 2004-04-27 Duke University Temperature-sensitive liposomal formulation
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
GB0111279D0 (en) * 2001-05-10 2001-06-27 Nycomed Imaging As Radiolabelled liposomes
EP1490027A4 (en) * 2002-03-05 2010-11-10 Transave Inc METHODS OF TRAPPING BIOACTIVE AGENT IN A LIPOSOME OR LIPID COMPLEX
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
JP5118302B2 (ja) * 2002-10-29 2013-01-16 トランセイブ， インク． 抗感染剤の徐放
US7879351B2 (en) 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
CA2507263A1 (en) * 2002-11-26 2004-06-10 Gilead Sciences, Inc. Liposomal formulations
CA2838111C (en) 2005-12-08 2016-01-19 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US20100196455A1 (en) * 2007-05-04 2010-08-05 Transave, Inc. Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
CN108743537B (zh) 2012-05-21 2021-06-11 英斯麦德公司 治疗肺部感染的系统
KR102115718B1 (ko) 2012-07-30 2020-05-28 마티나스 바이오파마 나노테크놀로지스, 인코포레이티드 대두 포스파티딜세린으로 제조된 코클리에이트
US10124066B2 (en) 2012-11-29 2018-11-13 Insmed Incorporated Stabilized vancomycin formulations
ES2820226T3 (es) * 2014-05-15 2021-04-20 Insmed Inc Métodos para tratar infecciones pulmonares micobacterianas no tuberculosas
KR102367801B1 (ko) * 2018-02-07 2022-02-24 제이에프이 스틸 가부시키가이샤 고Mn강 및 그의 제조 방법
EP3773505A4 (en) 2018-03-30 2021-12-22 Insmed Incorporated PROCESS FOR THE CONTINUOUS MANUFACTURING OF LIPOSOMAL MEDICINAL PRODUCTS

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5782311A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4522803A (en) * 1983-02-04 1985-06-11 The Liposome Company, Inc. Stable plurilamellar vesicles, their preparation and use
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
US4981692A (en) * 1983-03-24 1991-01-01 The Liposome Company, Inc. Therapeutic treatment by intramammary infusion
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
CA1237670A (en) * 1983-05-26 1988-06-07 Andrew S. Janoff Drug preparations of reduced toxicity
CA1237671A (en) * 1983-08-01 1988-06-07 Michael W. Fountain Enhancement of pharmaceutical activity
DE3585967D1 (de) * 1984-03-08 1992-06-11 Phares Pharma Holland Liposombildende zusammensetzung.
JPS6176414A (ja) * 1984-09-21 1986-04-18 Shionogi & Co Ltd リポソーム製剤の製法
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US5409704A (en) * 1985-06-26 1995-04-25 The Liposome Company, Inc. Liposomes comprising aminoglycoside phosphates and methods of production and use
US5023087A (en) * 1986-02-10 1991-06-11 Liposome Technology, Inc. Efficient method for preparation of prolonged release liposome-based drug delivery system
US5043107A (en) * 1986-08-21 1991-08-27 Vestar Research, Inc. Preparation small unilamellar vesicles including polyene antifungal antibiotics
US4933121A (en) * 1986-12-10 1990-06-12 Ciba Corning Diagnostics Corp. Process for forming liposomes
EP0500143A3 (en) * 1986-12-23 1993-03-03 The Liposome Company, Inc. Pharmaceutical composition comprising an aminoglycoside phosphate
US5043166A (en) * 1987-01-09 1991-08-27 Hadasit Medical Research, Inc. Liposome/anthraquinone drug composition and method
JP2877160B2 (ja) * 1987-07-29 1999-03-31 ザ リポソーム カンパニー，インコーポレイテッド 粒子のサイズによる分離方法
US4946683A (en) * 1987-11-18 1990-08-07 Vestar, Inc. Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US4952405A (en) * 1988-10-20 1990-08-28 Liposome Technology, Inc. Method of treating M. avium infection
US5043165A (en) * 1988-12-14 1991-08-27 Liposome Technology, Inc. Novel liposome composition for sustained release of steroidal drugs
US5270052A (en) * 1991-04-19 1993-12-14 New England Medical Center Hospitals, Inc. Methods and compositions for treatment of infection by intracellular parasites
CA2093381A1 (en) * 1992-04-07 1993-10-08 Hideyuki Sawahara Liposome formulation and process for production thereof
PT100486B (pt) * 1992-05-14 1999-07-30 Ineti Inst Nac Engenh E Tecnol Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
US5276452A (en) * 1992-06-24 1994-01-04 Raytheon Company Scan compensation for array antenna on a curved surface
JP3325665B2 (ja) * 1993-09-10 2002-09-17 三菱化学株式会社 オレフィン重合用触媒およびこれを用いたオレフィン重合体の製造方法

Also Published As

Publication number Publication date
CA2150832A1 (en) 1994-06-09
DE69326017D1 (de) 1999-09-16
CA2150832C (en) 2000-01-11
EP0671904B1 (en) 1999-08-11
JP4084846B2 (ja) 2008-04-30
AU3244393A (en) 1994-06-22
DE69326017T2 (de) 1999-12-23
EP0671904A1 (en) 1995-09-20
US5756121A (en) 1998-05-26
ES2134846T3 (es) 1999-10-16
WO1994012155A1 (en) 1994-06-09
WO1994012156A1 (en) 1994-06-09
AU668179B2 (en) 1996-04-26
GR3031548T3 (en) 2000-01-31
ATE183082T1 (de) 1999-08-15
JP2005320341A (ja) 2005-11-17
JPH09506855A (ja) 1997-07-08
AU4246393A (en) 1994-06-22

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