DK0652879T3 - 1-Azaadamantanderivater som 5-HT4-agonister eller -antagonister og/eller 5-HT3-antagonister - Google Patents
1-Azaadamantanderivater som 5-HT4-agonister eller -antagonister og/eller 5-HT3-antagonisterInfo
- Publication number
- DK0652879T3 DK0652879T3 DK93916671T DK93916671T DK0652879T3 DK 0652879 T3 DK0652879 T3 DK 0652879T3 DK 93916671 T DK93916671 T DK 93916671T DK 93916671 T DK93916671 T DK 93916671T DK 0652879 T3 DK0652879 T3 DK 0652879T3
- Authority
- DK
- Denmark
- Prior art keywords
- antagonists
- agonists
- azaadamantane derivatives
- azaadamantane
- image
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/919,679 US5840903A (en) | 1992-07-27 | 1992-07-27 | 4-aminomethyl-1-azaadamantane derived benzamides |
PCT/US1993/005945 WO1994002482A1 (fr) | 1992-07-27 | 1993-06-25 | Derives de 1-azaadamantane utilises comme agonistes ou antagonistes de 5-ht |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0652879T3 true DK0652879T3 (da) | 1999-10-25 |
Family
ID=25442463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93916671T DK0652879T3 (da) | 1992-07-27 | 1993-06-25 | 1-Azaadamantanderivater som 5-HT4-agonister eller -antagonister og/eller 5-HT3-antagonister |
Country Status (11)
Country | Link |
---|---|
US (2) | US5840903A (fr) |
EP (1) | EP0652879B1 (fr) |
JP (1) | JP3383668B2 (fr) |
AT (1) | ATE178900T1 (fr) |
AU (1) | AU4644893A (fr) |
CA (1) | CA2136837A1 (fr) |
DE (1) | DE69324492T2 (fr) |
DK (1) | DK0652879T3 (fr) |
ES (1) | ES2132245T3 (fr) |
GR (1) | GR3030506T3 (fr) |
WO (1) | WO1994002482A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001064202A2 (fr) | 2000-03-01 | 2001-09-07 | Euro-Celtique S.A. | Traitement de troubles gastro-intestinaux fonctionnels |
US7897766B2 (en) * | 2005-09-23 | 2011-03-01 | Abbott Laboratories | Amino-aza-adamantane derivatives and methods of use |
US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
EP2124562B1 (fr) | 2007-03-09 | 2016-04-20 | Second Genome, Inc. | Composés de bicyclohétéroaryle utilisés comme modulateurs de p2x7 et leurs utilisations |
US8163914B2 (en) | 2007-03-23 | 2012-04-24 | Abbott Laboratories | Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof |
CN101641357B (zh) * | 2007-03-23 | 2013-09-18 | Abbvie公司 | 4-取代的氮杂金刚烷衍生物及其使用方法 |
MX2009010173A (es) | 2007-03-23 | 2009-10-12 | Abbott Lab | Derivados de aminometil aza-adamantano y uso de los mismos como moduladores selectivos del receptor de acetilcolina nicotinico alfa-7 neuronal (nnrs). |
US8163916B2 (en) * | 2007-03-23 | 2012-04-24 | Abbott Laboratories | Azaadamantane ester and carbamate derivatives and methods of use thereof |
SG188307A1 (en) | 2010-09-23 | 2013-04-30 | Abbvie Inc | Monohydrate of an azaadamantane derivative |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2514006A1 (fr) * | 1981-10-05 | 1983-04-08 | Nativelle Sa Ets | Acylamino-4 aza-1 adamantanes, procede pour leur preparation, et application en therapeutique |
DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
ATE86110T1 (de) * | 1984-12-20 | 1993-03-15 | Sandoz Ag | Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten. |
GB8523211D0 (en) * | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
GB8525844D0 (en) * | 1985-10-19 | 1985-11-20 | Beecham Group Plc | Compounds |
US4910193A (en) * | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
HU895334D0 (en) * | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
EP0350130A3 (fr) * | 1988-07-07 | 1991-07-10 | Duphar International Research B.V | 1H-indazoles 1,7-annelés substitués |
US4992461A (en) * | 1989-09-11 | 1991-02-12 | G. D. Searle & Co. | N-azabicyclo(3.3.0)octane amides of aromatic acids, compositions, and methods of use thereof |
US5140023A (en) * | 1990-04-27 | 1992-08-18 | G. D. Searle & Co. | Azatetracycle compounds |
-
1992
- 1992-07-27 US US07/919,679 patent/US5840903A/en not_active Expired - Fee Related
-
1993
- 1993-06-25 DE DE69324492T patent/DE69324492T2/de not_active Expired - Fee Related
- 1993-06-25 AT AT93916671T patent/ATE178900T1/de not_active IP Right Cessation
- 1993-06-25 DK DK93916671T patent/DK0652879T3/da active
- 1993-06-25 WO PCT/US1993/005945 patent/WO1994002482A1/fr active IP Right Grant
- 1993-06-25 CA CA002136837A patent/CA2136837A1/fr not_active Abandoned
- 1993-06-25 ES ES93916671T patent/ES2132245T3/es not_active Expired - Lifetime
- 1993-06-25 JP JP50446094A patent/JP3383668B2/ja not_active Expired - Fee Related
- 1993-06-25 EP EP93916671A patent/EP0652879B1/fr not_active Expired - Lifetime
- 1993-06-25 AU AU46448/93A patent/AU4644893A/en not_active Abandoned
-
1995
- 1995-05-18 US US08/443,545 patent/US5643917A/en not_active Expired - Fee Related
-
1999
- 1999-06-15 GR GR990401581T patent/GR3030506T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0652879A1 (fr) | 1995-05-17 |
JP3383668B2 (ja) | 2003-03-04 |
AU4644893A (en) | 1994-02-14 |
JPH07509242A (ja) | 1995-10-12 |
US5840903A (en) | 1998-11-24 |
US5643917A (en) | 1997-07-01 |
DE69324492D1 (de) | 1999-05-20 |
DE69324492T2 (de) | 1999-09-02 |
EP0652879B1 (fr) | 1999-04-14 |
CA2136837A1 (fr) | 1994-02-03 |
ATE178900T1 (de) | 1999-04-15 |
GR3030506T3 (en) | 1999-10-29 |
WO1994002482A1 (fr) | 1994-02-03 |
ES2132245T3 (es) | 1999-08-16 |
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