DK0644929T3 - System og fremgangsmåde til transplantation af celler - Google Patents

System og fremgangsmåde til transplantation af celler

Info

Publication number
DK0644929T3
DK0644929T3 DK93915336T DK93915336T DK0644929T3 DK 0644929 T3 DK0644929 T3 DK 0644929T3 DK 93915336 T DK93915336 T DK 93915336T DK 93915336 T DK93915336 T DK 93915336T DK 0644929 T3 DK0644929 T3 DK 0644929T3
Authority
DK
Denmark
Prior art keywords
transplanting cells
genetic material
cells
microneedle
medicament
Prior art date
Application number
DK93915336T
Other languages
English (en)
Inventor
Elof Eriksson
Peter M Vogt
Original Assignee
Applied Tissue Technologies Ll
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Tissue Technologies Ll filed Critical Applied Tissue Technologies Ll
Application granted granted Critical
Publication of DK0644929T3 publication Critical patent/DK0644929T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0076—Tattooing apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/0247—Semi-permanent or permanent transcutaneous or percutaneous access sites to the inside of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK93915336T 1992-06-11 1993-06-11 System og fremgangsmåde til transplantation af celler DK0644929T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/897,357 US5423778A (en) 1989-12-14 1992-06-11 System and method for transplantation of cells
PCT/US1993/005665 WO1993025660A1 (en) 1992-06-11 1993-06-11 System and method for transplantation of cells

Publications (1)

Publication Number Publication Date
DK0644929T3 true DK0644929T3 (da) 2000-11-06

Family

ID=25407820

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93915336T DK0644929T3 (da) 1992-06-11 1993-06-11 System og fremgangsmåde til transplantation af celler

Country Status (12)

Country Link
US (1) US5423778A (da)
EP (2) EP0644929B1 (da)
JP (1) JPH08509356A (da)
AT (2) ATE195551T1 (da)
AU (1) AU4535693A (da)
CA (1) CA2137914A1 (da)
DE (2) DE69329241T2 (da)
DK (1) DK0644929T3 (da)
ES (1) ES2149818T3 (da)
GR (1) GR3034758T3 (da)
PT (1) PT644929E (da)
WO (1) WO1993025660A1 (da)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
CA2137275A1 (en) * 1992-06-03 1993-12-09 Richard L. Eckert Bandage for continuous application of biologicals
JP3573488B2 (ja) * 1994-04-11 2004-10-06 独立行政法人 科学技術振興機構 毛乳頭細胞の長期継代培養法
US6911216B1 (en) 1994-10-12 2005-06-28 Genzyme Corporation Targeted delivery via biodegradable polymers
US6638264B1 (en) 1995-05-16 2003-10-28 Biostratum Incorporation Perfusion apparatus and methods for pharmaceutical delivery
US6342214B1 (en) * 1995-05-16 2002-01-29 Karl Tryggvason Method for viral vector delivery
EP0846162A1 (en) * 1995-08-25 1998-06-10 Lifecell Corporation Reconstituted skin
WO1998013076A1 (en) * 1996-09-24 1998-04-02 Brigham And Women's Hospital Cultured cell-seeded fibrous lattice for tissue replacement
GB9708692D0 (en) * 1997-04-30 1997-06-18 Jahoda Colin A B Dermal sheath tissue and/or cells derived therefrom in wound healing
US7419661B2 (en) 1997-04-30 2008-09-02 The Centre Of Excellence For Life Sciences Limited Dermal sheath tissue in wound healing
GB9715085D0 (en) 1997-07-18 1997-09-24 Jahoda Amanda J Gene therapy vehicle
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6884427B1 (en) * 1999-02-08 2005-04-26 Aderans Research Institute, Inc. Filamentary means for introducing agents into tissue of a living host
AU2001247880A1 (en) * 2000-03-28 2001-10-08 University Of Iowa Research Foundation Methods to prepare and use epidermal stem cells
KR100377784B1 (ko) * 2000-06-22 2003-03-29 (주)트리코진 모근 간엽세포로부터 제조된 진피대체물
DE60138572D1 (de) 2000-07-31 2009-06-10 Univ Bar Ilan Methoden und pharmazeutische zusammensetzungen zur wundheilung
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
WO2002015952A1 (en) * 2000-08-08 2002-02-28 Bioamide, Inc. Scaffolds for tissue engineered hair
US7651507B2 (en) * 2003-03-03 2010-01-26 Kci Licensing, Inc. Tissue processing system
US7494482B2 (en) 2001-05-15 2009-02-24 The Brigham And Women's Hospital, Inc. Methods and apparatus for application of micro-mechanical forces to tissues
US20040068284A1 (en) * 2002-01-29 2004-04-08 Barrows Thomas H. Method for stimulating hair growth and kit for carrying out said method
JP3638589B2 (ja) * 2003-05-23 2005-04-13 花王株式会社 再構成皮膚の構築方法
NZ545086A (en) 2003-08-07 2011-06-30 Healor Ltd Pharmaceutical compositions and methods for accelerating wound healing
AU2004266161A1 (en) * 2003-08-26 2005-03-03 Alza Corporation Device and method for intradermal cell implantation
US7597885B2 (en) * 2004-03-26 2009-10-06 Aderans Research Institute, Inc. Tissue engineered biomimetic hair follicle graft
AR050212A1 (es) * 2004-08-13 2006-10-04 Aderans Res Inst Inc Organogenesis a partir de celulas disociadas
CA2586856C (en) 2004-11-11 2015-04-07 The General Hospital Corporation Parathyroid hormone receptor activation and stem and progenitor cell expansion
CA2625674C (en) 2005-08-29 2015-04-14 Healor Ltd. Methods and compositions for prevention and treatment of diabetic and aged skin
JP5153638B2 (ja) * 2005-10-17 2013-02-27 アデランス リサーチ インスティテュート インコーポレイテッド 毛包前駆細胞を皮膚に送達する方法
AR057628A1 (es) * 2005-11-22 2007-12-05 Aderans Res Inst Inc Injertos capilares derivados de cabello extirpado
AR057629A1 (es) * 2005-11-22 2007-12-05 Aderans Res Inst Inc Injerto de foliculos pilosos de piel obtenida por ingenieria de tejidos
EP1986731A4 (en) * 2006-02-09 2012-11-07 Aderans Res Inst Inc APPARATUS AND METHODS FOR DELIVERING FLUID AND MATERIAL TO A SUBJECT
US7985537B2 (en) * 2007-06-12 2011-07-26 Aderans Research Institute, Inc. Methods for determining the hair follicle inductive properties of a composition
GB2455962A (en) 2007-12-24 2009-07-01 Ethicon Inc Reinforced adhesive backing sheet, for plaster
US8372049B2 (en) 2008-03-05 2013-02-12 Kci Licensing, Inc. Dressing and method for applying reduced pressure to and collecting and storing fluid from a tissue site
US20110091427A1 (en) * 2009-10-02 2011-04-21 Baxter International Inc. Methods for treating a kidney injury
WO2011083482A2 (en) 2010-01-11 2011-07-14 Healor Ltd. Method for treatment of psoriasis
US8814842B2 (en) 2010-03-16 2014-08-26 Kci Licensing, Inc. Delivery-and-fluid-storage bridges for use with reduced-pressure systems
US8608117B2 (en) * 2011-01-19 2013-12-17 The Pullman Company Isolator having push and turn mounting
GB2488749A (en) 2011-01-31 2012-09-12 Systagenix Wound Man Ip Co Bv Laminated silicone coated wound dressing
GB201106491D0 (en) 2011-04-15 2011-06-01 Systagenix Wound Man Ip Co Bv Patterened silicone coating
CN103987348B (zh) 2011-12-16 2016-05-11 凯希特许有限公司 可释放的医用布单
US10940047B2 (en) 2011-12-16 2021-03-09 Kci Licensing, Inc. Sealing systems and methods employing a hybrid switchable drape
US20130216495A1 (en) 2012-02-21 2013-08-22 Baxter Healthcare Sa Pharmaceutical composition comprising cd34+ cells
USD690004S1 (en) 2012-03-16 2013-09-17 Aderans Research Institute, Inc. Holder for a device for delivering cellular material and physiologic fluids
CN111991092A (zh) 2012-11-16 2020-11-27 凯希特许有限公司 具有图案粘合剂层的医用盖布及其制造方法
GB201222770D0 (en) 2012-12-18 2013-01-30 Systagenix Wound Man Ip Co Bv Wound dressing with adhesive margin
US9283118B2 (en) 2013-03-14 2016-03-15 Kci Licensing, Inc. Absorbent dressing with hybrid drape
EP3578209B1 (en) 2013-08-26 2023-12-20 3M Innovative Properties Company Dressing interface with moisture controlling feature and sealing function
US10946124B2 (en) 2013-10-28 2021-03-16 Kci Licensing, Inc. Hybrid sealing tape
US9956120B2 (en) 2013-10-30 2018-05-01 Kci Licensing, Inc. Dressing with sealing and retention interface
EP3062833B1 (en) 2013-10-30 2019-04-17 KCI Licensing, Inc. Absorbent conduit and system
EP3513773A1 (en) 2013-10-30 2019-07-24 KCI Licensing, Inc. Condensate absorbing and dissipating system
ES2670710T3 (es) 2013-10-30 2018-05-31 Kci Licensing, Inc. Apósito con perforaciones dimensionadas diferencialmente
JP6347960B2 (ja) * 2014-01-29 2018-06-27 Ａｓｔｉ株式会社 マイクロニードルユニットと注射装置
WO2015130471A1 (en) 2014-02-28 2015-09-03 Kci Licensing, Inc. Hybrid drape having a gel-coated perforated mesh
US11026844B2 (en) 2014-03-03 2021-06-08 Kci Licensing, Inc. Low profile flexible pressure transmission conduit
US10406266B2 (en) 2014-05-02 2019-09-10 Kci Licensing, Inc. Fluid storage devices, systems, and methods
EP3854361B8 (en) 2014-06-05 2024-03-27 Solventum Intellectual Properties Company Dressing with fluid acquisition and distribution characteristics
WO2016100098A1 (en) 2014-12-17 2016-06-23 Kci Licensing, Inc. Dressing with offloading capability
EP3294245B1 (en) 2015-05-08 2019-09-04 KCI Licensing, Inc. Low acuity dressing with integral pump
JP6752231B2 (ja) 2015-06-01 2020-09-09 カリフォルニア インスティテュート オブ テクノロジー 抗原を用いて特異的集団に関してｔ細胞をスクリーニングするための組成物および方法
US11096830B2 (en) 2015-09-01 2021-08-24 Kci Licensing, Inc. Dressing with increased apposition force
US10973694B2 (en) 2015-09-17 2021-04-13 Kci Licensing, Inc. Hybrid silicone and acrylic adhesive cover for use with wound treatment
US9636491B1 (en) 2016-06-08 2017-05-02 Eclipse Aesthetics, LLC Disposable needle cartridges having absorbing contaminant barriers
US9629991B1 (en) 2016-06-08 2017-04-25 Eclipse Aesthetics, LLC Disposable radio frequency needle cartridges having absorbing containment barriers
US10220195B2 (en) 2016-06-08 2019-03-05 Eclipse Medcorp, Llc Radio frequency needling device for use with disposable needle cartridges
WO2018170132A1 (en) 2017-03-14 2018-09-20 University Of Connecticut Biodegradable pressure sensor
CN108283533A (zh) * 2017-12-29 2018-07-17 广东美捷威通生物科技有限公司 一种创面原位细胞移植培养装置
US11826495B2 (en) 2019-03-01 2023-11-28 University Of Connecticut Biodegradable piezoelectric ultrasonic transducer system
US11745001B2 (en) 2020-03-10 2023-09-05 University Of Connecticut Therapeutic bandage

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB641061A (en) * 1947-09-06 1950-08-02 James Donald Maclaurin Improvements in method of treating wounds
US3026874A (en) * 1959-11-06 1962-03-27 Robert C Stevens Wound shield
US3288140A (en) * 1963-10-04 1966-11-29 John J Mccarthy Means for treating surface wounds
US3367332A (en) * 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3580254A (en) * 1967-07-13 1971-05-25 Henry P Stuart Bandage containing a medicinal material and method of using
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US4304866A (en) * 1979-11-14 1981-12-08 Massachusetts Institute Of Technology Transplantable sheets of living keratinous tissue
US4347841A (en) * 1981-03-11 1982-09-07 Human Oltoanyagtermelo Es Kutato Intezet Biological wound covering and method for producing same
US4980286A (en) * 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
ATE68013T1 (de) * 1985-07-05 1991-10-15 Whitehead Biomedical Inst Expression von fremdem genetischem material in epithelzellen.
US4767746A (en) * 1985-12-04 1988-08-30 Trustees Of Boston University Method for enhancement of healing of epithelial wounds in mammals
US4888291A (en) * 1987-06-19 1989-12-19 President And Fellows Of Harvard College Human epithelium originating from cell cultures
US4788971A (en) * 1987-07-13 1988-12-06 Hill Top Research, Inc. Patch system for use on the skin
US5175092A (en) * 1989-05-04 1992-12-29 Millipore Corporation Vitro toxicology kit and method therefor
CA2071827C (en) * 1989-12-14 1998-08-18 Brigham And Women's Hospital A treatment system for wounds and other disorders and a method for treating wounds and other skin disorders
WO1992015676A1 (en) * 1991-03-08 1992-09-17 The Salk Institute For Biological Studies Somatic cell gene therapy
US5201728A (en) * 1991-05-03 1993-04-13 Giampapa Vincent C Subcutaneous implantable multiple-agent delivery system

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EP0644929B1 (en) 2000-08-16
ATE195551T1 (de) 2000-09-15
DE69329241D1 (de) 2000-09-21
AU4535693A (en) 1994-01-04
DE69334257D1 (de) 2009-02-26
US5423778A (en) 1995-06-13
CA2137914A1 (en) 1993-12-23
ES2149818T3 (es) 2000-11-16
EP0955359A1 (en) 1999-11-10
ATE420156T1 (de) 2009-01-15
EP0955359B1 (en) 2009-01-07
JPH08509356A (ja) 1996-10-08
DE69329241T2 (de) 2001-02-22
WO1993025660A1 (en) 1993-12-23
GR3034758T3 (en) 2001-02-28
EP0644929A1 (en) 1995-03-29
PT644929E (pt) 2001-02-28

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