DE68927104T2 - Gentherapie unter verwendung von genschmelzen für genetische und erworbene störungen - Google Patents
Gentherapie unter verwendung von genschmelzen für genetische und erworbene störungenInfo
- Publication number
- DE68927104T2 DE68927104T2 DE68927104T DE68927104T DE68927104T2 DE 68927104 T2 DE68927104 T2 DE 68927104T2 DE 68927104 T DE68927104 T DE 68927104T DE 68927104 T DE68927104 T DE 68927104T DE 68927104 T2 DE68927104 T2 DE 68927104T2
- Authority
- DE
- Germany
- Prior art keywords
- gene
- genetic
- melts
- acquired disorders
- gene therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20278388A | 1988-06-03 | 1988-06-03 | |
PCT/US1989/002450 WO1989012109A1 (en) | 1988-06-03 | 1989-06-05 | Gene therapy using gene fusions for genetic or acquired disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68927104D1 DE68927104D1 (de) | 1996-10-10 |
DE68927104T2 true DE68927104T2 (de) | 1997-03-06 |
Family
ID=22751243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68927104T Expired - Lifetime DE68927104T2 (de) | 1988-06-03 | 1989-06-05 | Gentherapie unter verwendung von genschmelzen für genetische und erworbene störungen |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0420911B1 (de) |
JP (1) | JP2949440B2 (de) |
AT (1) | ATE142269T1 (de) |
AU (1) | AU634162B2 (de) |
CA (1) | CA1339654C (de) |
DE (1) | DE68927104T2 (de) |
IL (1) | IL90514A (de) |
WO (1) | WO1989012109A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU637986B2 (en) * | 1988-10-21 | 1993-06-17 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Transgenic animals for testing multidrug resistance |
US5858784A (en) * | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
US6627615B1 (en) | 1991-12-17 | 2003-09-30 | The Regents Of The University Of California | Methods and compositions for in vivo gene therapy |
US5756353A (en) * | 1991-12-17 | 1998-05-26 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol-and liposome-based delivery |
US6806084B1 (en) | 1992-06-04 | 2004-10-19 | The Regents Of The University Of California | Methods for compositions for in vivo gene delivery |
EP0646178A1 (de) * | 1992-06-04 | 1995-04-05 | The Regents Of The University Of California | Expression kassette mit im säugetier wirt funktionnellen regulator sequenzen |
DE4238778C2 (de) * | 1992-11-12 | 1995-11-02 | Max Delbrueck Centrum | Vektor zur Expression von therapeutisch relevanten Genen |
US5968735A (en) * | 1992-11-12 | 1999-10-19 | Max Delbruck-Centrum Fur Molekular Medizin Berlin | Vector for the expression of therapy-relevant genes |
US6344445B1 (en) | 1995-10-19 | 2002-02-05 | Cantab Pharmaceutical Research Limited | Herpes virus vectors and their uses |
GB9622500D0 (en) | 1996-10-29 | 1997-01-08 | Oxford Biomedica Ltd | Therapeutic gene |
GB2333527B (en) * | 1996-10-29 | 2001-05-02 | Oxford Biomedica Ltd | Therapeutic gene |
US6924123B2 (en) | 1996-10-29 | 2005-08-02 | Oxford Biomedica (Uk) Limited | Lentiviral LTR-deleted vector |
PL3461888T3 (pl) | 2012-09-11 | 2020-12-14 | Corning Incorporated | Ulegające zużyciu krioprezerwowane komórki wykazujące przejściową nadekspresję genu(-ów) kodującego(-ych) białko(-a) transportera leku i/lub enzym(y) metabolizujący(-e) lek |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU197349B (en) * | 1982-05-25 | 1989-03-28 | Lilly Co Eli | Process for producing cloning vectors usable for the expression of growth hormones |
DE3715033A1 (de) * | 1987-05-06 | 1988-11-17 | Hoechst Ag | Verfahren zur isolierung von fusionsproteinen |
AU637986B2 (en) * | 1988-10-21 | 1993-06-17 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Transgenic animals for testing multidrug resistance |
DK0478696T3 (da) * | 1989-06-23 | 1995-06-26 | Us Health | Effektiv fremgangsmåde til identificerbar udtrykkelse af ikke-selekterbare gener |
-
1989
- 1989-06-02 IL IL9051489A patent/IL90514A/en not_active IP Right Cessation
- 1989-06-02 CA CA000601635A patent/CA1339654C/en not_active Expired - Fee Related
- 1989-06-05 AT AT89907509T patent/ATE142269T1/de not_active IP Right Cessation
- 1989-06-05 AU AU37788/89A patent/AU634162B2/en not_active Ceased
- 1989-06-05 DE DE68927104T patent/DE68927104T2/de not_active Expired - Lifetime
- 1989-06-05 EP EP89907509A patent/EP0420911B1/de not_active Expired - Lifetime
- 1989-06-05 JP JP1506880A patent/JP2949440B2/ja not_active Expired - Lifetime
- 1989-06-05 WO PCT/US1989/002450 patent/WO1989012109A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP2949440B2 (ja) | 1999-09-13 |
EP0420911A1 (de) | 1991-04-10 |
AU3778889A (en) | 1990-01-05 |
AU634162B2 (en) | 1993-02-18 |
WO1989012109A1 (en) | 1989-12-14 |
CA1339654C (en) | 1998-02-03 |
IL90514A (en) | 1995-10-31 |
EP0420911A4 (en) | 1991-11-13 |
ATE142269T1 (de) | 1996-09-15 |
DE68927104D1 (de) | 1996-10-10 |
EP0420911B1 (de) | 1996-09-04 |
JPH03505818A (ja) | 1991-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |