DK0642362T3 - Nye bioaktive overtræk og deres fremstilling og anvendelse - Google Patents

Nye bioaktive overtræk og deres fremstilling og anvendelse

Info

Publication number
DK0642362T3
DK0642362T3 DK93908970T DK93908970T DK0642362T3 DK 0642362 T3 DK0642362 T3 DK 0642362T3 DK 93908970 T DK93908970 T DK 93908970T DK 93908970 T DK93908970 T DK 93908970T DK 0642362 T3 DK0642362 T3 DK 0642362T3
Authority
DK
Denmark
Prior art keywords
pct
preparation
application
biomedical
sec
Prior art date
Application number
DK93908970T
Other languages
English (en)
Inventor
Panjian Li
Ilkka Kangasniemi
Original Assignee
Axidental Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axidental Oy filed Critical Axidental Oy
Application granted granted Critical
Publication of DK0642362T3 publication Critical patent/DK0642362T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • A61L27/06Titanium or titanium alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/306Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00592Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/12Materials or treatment for tissue regeneration for dental implants or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/24Materials or treatment for tissue regeneration for joint reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prostheses (AREA)
DK93908970T 1992-04-23 1993-04-21 Nye bioaktive overtræk og deres fremstilling og anvendelse DK0642362T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI921802A FI91713C (fi) 1992-04-23 1992-04-23 Uusia bioaktiivisia pinnotteita ja niiden valmistus ja käyttö
PCT/FI1993/000163 WO1993021969A1 (en) 1992-04-23 1993-04-21 Novel bioactive coatings and their preparation and use

Publications (1)

Publication Number Publication Date
DK0642362T3 true DK0642362T3 (da) 1999-08-23

Family

ID=8535165

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908970T DK0642362T3 (da) 1992-04-23 1993-04-21 Nye bioaktive overtræk og deres fremstilling og anvendelse

Country Status (14)

Country Link
US (1) US5612049A (da)
EP (1) EP0642362B1 (da)
JP (1) JP3220150B2 (da)
KR (1) KR950700764A (da)
AT (1) ATE174803T1 (da)
AU (1) AU672198B2 (da)
CA (1) CA2118036C (da)
DE (1) DE69322779T2 (da)
DK (1) DK0642362T3 (da)
ES (1) ES2125979T3 (da)
FI (1) FI91713C (da)
GR (1) GR3029407T3 (da)
RU (1) RU2124329C1 (da)
WO (1) WO1993021969A1 (da)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
DE4431401A1 (de) * 1994-08-24 1996-02-29 Max Delbrueck Centrum Lebendvakzine gegen Tumorerkrankungen
DE4431862C2 (de) * 1994-09-07 1997-12-11 Dot Duennschicht Und Oberflaec Verfahren zur Beschichtung von Metall- und Keramikoberflächen mit Hydroxylapatit
JP2795824B2 (ja) * 1995-05-12 1998-09-10 オオタ株式会社 チタン系インプラントの表面処理方法及び生体親和性チタン系インプラント
US6764690B2 (en) * 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6387700B1 (en) 1996-11-04 2002-05-14 The Reagents Of The University Of Michigan Cationic peptides, Cys-Trp-(LYS)n, for gene delivery
JP3275032B2 (ja) * 1997-03-03 2002-04-15 独立行政法人産業技術総合研究所 環境浄化材料及びその製造方法
US6736849B2 (en) 1998-03-11 2004-05-18 Depuy Products, Inc. Surface-mineralized spinal implants
US6139585A (en) * 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
US6395253B2 (en) 1998-04-23 2002-05-28 The Regents Of The University Of Michigan Microspheres containing condensed polyanionic bioactive agents and methods for their production
WO1999066966A1 (fr) * 1998-06-22 1999-12-29 Anatoly Dosta Revetement de type film fin pour implant osseux
US6770740B1 (en) 1999-07-13 2004-08-03 The Regents Of The University Of Michigan Crosslinked DNA condensate compositions and gene delivery methods
CA2430755C (en) * 2000-12-04 2011-02-01 Uwe Emil Grussner Method of producing a partial or complete active ingredient coating on and in implants and onplants
WO2002089864A1 (en) * 2001-05-02 2002-11-14 Japan Science And Technology Corporation Anatase-type titanium dioxide/organic polymer composite materials suitable for artificial bone
DE10161827A1 (de) * 2001-12-15 2003-06-26 Dot Gmbh Verfahren zur Beschichtung eines Substrats mit Calciumphosphat
US7132015B2 (en) * 2002-02-20 2006-11-07 University Of Southern California Materials for dental and biomedical application
WO2005007802A2 (en) * 2002-03-15 2005-01-27 The Trustees Of The University Of Pennsylvania Fibrous composite for tissue engineering
WO2003086495A1 (en) * 2002-04-09 2003-10-23 Astra Tech Ab Medical prosthetic devices having improved biocompatibility
US7410502B2 (en) * 2002-04-09 2008-08-12 Numat As Medical prosthetic devices having improved biocompatibility
GB0208642D0 (en) * 2002-04-16 2002-05-22 Accentus Plc Metal implants
DE10243132B4 (de) * 2002-09-17 2006-09-14 Biocer Entwicklungs Gmbh Antiinfektiöse, biokompatible Titanoxid-Beschichtungen für Implantate sowie Verfahren zu deren Herstellung
US6931278B1 (en) 2002-12-06 2005-08-16 Pacesetter, Inc. Implantable cardioverter defibrillator having fast action operation
US7067169B2 (en) * 2003-06-04 2006-06-27 Chemat Technology Inc. Coated implants and methods of coating
US20040267376A1 (en) * 2003-06-25 2004-12-30 Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd) Ceramic member for medical implant and its production method
US7419680B2 (en) * 2003-10-01 2008-09-02 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
US9199005B2 (en) * 2003-10-01 2015-12-01 New York University Calcium phosphate-based materials containing zinc, magnesium, fluoride and carbonate
GB0405680D0 (en) * 2004-03-13 2004-04-21 Accentus Plc Metal implants
US7785648B2 (en) * 2004-09-22 2010-08-31 New York University Adherent apatite coating on titanium substrate using chemical deposition
US8814567B2 (en) * 2005-05-26 2014-08-26 Zimmer Dental, Inc. Dental implant prosthetic device with improved osseointegration and esthetic features
US7344643B2 (en) * 2005-06-30 2008-03-18 Siemens Water Technologies Holding Corp. Process to enhance phosphorus removal for activated sludge wastewater treatment systems
CA2620427C (en) 2005-08-30 2014-03-11 Zimmer Dental, Inc. Dental implant with improved osseointegration features
US8562346B2 (en) 2005-08-30 2013-10-22 Zimmer Dental, Inc. Dental implant for a jaw with reduced bone volume and improved osseointegration features
CA2629600C (en) * 2005-11-14 2011-11-01 Biomet 3I, Inc. Deposition of discrete nanoparticles on an implant surface
ITFI20060034A1 (it) 2006-02-03 2007-08-04 Colorobbia Italiana Spa Processo per la funzionalizzazione di superfici metalliche in titanio con particelle di titanio nanometriche e prodotti cosi' funzionalizzati
TW200744679A (en) * 2006-06-09 2007-12-16 Atomic Energy Council Plasma preparation method for containing titanium dioxide of multifunctional polymeric biomaterial
JP5268894B2 (ja) * 2006-06-12 2013-08-21 アクセンタス ピーエルシー 金属インプラント
EP2084311A2 (en) * 2006-09-27 2009-08-05 Yissum Research Development Company of the Hebrew University of Jerusalem Electrochemical co-deposition of sol-gel films
BRPI0718660A2 (pt) * 2006-11-10 2013-11-26 Sandvik Intellectual Property Materiais compósitos de implante cirúrgico e kits e métodos de fabricação.
AU2008206819B2 (en) * 2007-01-15 2013-07-11 Accentus Medical Limited Metal implants
US9149345B2 (en) * 2007-08-30 2015-10-06 Zimmer Dental, Inc. Multiple root implant
AU2008306596B2 (en) 2007-10-03 2013-04-04 Accentus Plc Method of manufacturing metal with biocidal properties
WO2009097218A1 (en) * 2008-01-28 2009-08-06 Biomet 3I, Llc Implant surface with increased hydrophilicity
US8899982B2 (en) 2008-07-02 2014-12-02 Zimmer Dental, Inc. Implant with structure for securing a porous portion
US9095396B2 (en) 2008-07-02 2015-08-04 Zimmer Dental, Inc. Porous implant with non-porous threads
US8231387B2 (en) 2008-07-02 2012-07-31 Zimmer, Inc. Porous implant with non-porous threads
US8562348B2 (en) 2008-07-02 2013-10-22 Zimmer Dental, Inc. Modular implant with secured porous portion
US20100114314A1 (en) 2008-11-06 2010-05-06 Matthew Lomicka Expandable bone implant
US9707058B2 (en) * 2009-07-10 2017-07-18 Zimmer Dental, Inc. Patient-specific implants with improved osseointegration
US8602782B2 (en) * 2009-11-24 2013-12-10 Zimmer Dental, Inc. Porous implant device with improved core
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
WO2013142118A1 (en) 2012-03-20 2013-09-26 Biomet 3I, Llc Surface treatment for an implant surface
DE102012021003B4 (de) 2012-10-26 2015-02-12 Otto Bock Healthcare Products Gmbh Perkutanes lmplantat und Verfahren zum Herstellen eines solchen lmplantates
RU2524764C1 (ru) * 2013-02-28 2014-08-10 Дмитрий Константинович Юдин Способ получения дентального имплантата погружного типа из титана или титанового сплава и дентальный имплантат из титана или титанового сплава
MX339086B (es) 2013-06-20 2016-05-09 Inmolecule Internat Ltd Nanomaterial de dioxido de titanio nanoparticulado modificado con grupos funcionales y con extractos citricos adsorbidos en la superficie para la eliminacion de amplio espectro de microorganismos.
RU2630578C1 (ru) * 2016-10-31 2017-09-11 федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский национальный исследовательский политехнический университет" Способ модифицирования поверхности титановых имплантатов
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
CN107397977B (zh) * 2017-08-03 2021-01-26 广东工业大学 3d打印金属基体表面改性的方法、3d打印金属基生物陶瓷支架及其制备方法
RU2687792C1 (ru) * 2018-05-07 2019-05-16 Сергей Вячеславович Купряхин Способ изготовления внутрикостного имплантата
KR102286394B1 (ko) * 2020-11-24 2021-08-06 주식회사 오스메딕 생체용 재료의 수산화인회석 코팅방법 및 이를 이용하여 제조된 수산화인회석이 코팅된 생체용 재료

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987006843A1 (en) * 1986-05-15 1987-11-19 Sumitomo Cement Co., Ltd. Artificial biocompatible material
US4737411A (en) * 1986-11-25 1988-04-12 University Of Dayton Controlled pore size ceramics particularly for orthopaedic and dental applications
SE464850B (sv) * 1989-07-19 1991-06-24 Ellem Bioteknik Ab Saett foer preparering av en implantatkropp genom behandling med en vaeteperoxidloesning
SE464911B (sv) * 1988-01-20 1991-07-01 Inst Applied Biotechnology Anti-inflammatoriskt medel, baserat paa reaktionsprodukten mellan h?712o?712 och titan, foerfarande foer dess framstaellning samt anvaendning daerav
US5152993A (en) * 1988-01-20 1992-10-06 Ellem Bioteknik Ab Method of preparing an implant body for implantation
US5032552A (en) * 1988-07-04 1991-07-16 Tdk Corporation Biomedical material

Also Published As

Publication number Publication date
GR3029407T3 (en) 1999-05-28
FI91713C (fi) 1994-08-10
KR100263555B1 (da) 2001-11-22
AU672198B2 (en) 1996-09-26
EP0642362A1 (en) 1995-03-15
RU2124329C1 (ru) 1999-01-10
ATE174803T1 (de) 1999-01-15
AU3954793A (en) 1993-11-29
DE69322779T2 (de) 1999-05-20
CA2118036C (en) 2005-02-15
KR950700764A (ko) 1995-02-20
US5612049A (en) 1997-03-18
JPH07505809A (ja) 1995-06-29
FI91713B (fi) 1994-04-29
WO1993021969A1 (en) 1993-11-11
FI921802A (fi) 1993-10-24
DE69322779D1 (de) 1999-02-04
FI921802A0 (fi) 1992-04-23
ES2125979T3 (es) 1999-03-16
RU94045951A (ru) 1996-09-20
CA2118036A1 (en) 1993-11-11
EP0642362B1 (en) 1998-12-23
JP3220150B2 (ja) 2001-10-22

Similar Documents

Publication Publication Date Title
DK0642362T3 (da) Nye bioaktive overtræk og deres fremstilling og anvendelse
ATE273036T1 (de) Verfahren zur herstellung von oxiden mit konstanter dicke auf zirconiumlegierungen
GB2317885A (en) Biomaterial
DE69332173T2 (de) Resorbierbare, bioaktive phospat-zemente
DK0699103T3 (da) Overflademodificerede, biokompatible membraner
FI932761A (fi) Foerfarande foer framstaellning av aktiva substanser innehaollande mikropartiklar av hydrolytiskt nedbrytbara polymerer
DE69028535T2 (de) Herstellung des vaskulären endothelialen zellwachstumsfaktors
PT1061940E (pt) Utilizacao de foliestatina para a producao de um medicamento para o tratamento de disturbios relacionados com os musculos
SE9901973L (sv) Implantat för applicering i ben och förfarande och användning vid sådant implantat
ATE211636T1 (de) Methode zum herstellen eines dentalproduktes
DE69029735T2 (de) Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse
CA2158134A1 (en) Supplemented tissue sealant
FR2514261B1 (fr) Nouvelle composition pour l'enrobage des aliments et des medicaments et granules ainsi enrobes
ES2157924T3 (es) Procedimiento para la reduccion de la adherencia de microorganismos.
ES8706581A1 (es) Un metodo para preparar un dispositivo biomedico conformado
De Groot Hydroxylapatite coatings for implants in surgery
GR3034161T3 (en) Pharmaceutical composition for preventing or treating.
Ravaglioli et al. Physico-chemical behaviour of a bioactive glass coating for metal prostheses
Ravaglioli et al. Materials for surgical use
Peltola et al. Apatite formation in a simulated body fluid on sol-gel derived titania coatings with effect of protein adsorption
DE50205874D1 (de) Gewebe zum chirurgischen verschluss von hernien
Nuesch et al. Metallic Implant
YU48230B (sh) Kristalni deoksispergvalin i postupak za njegovo pripremanje