DK0629210T3 - Peptidforbindelsesenhed, der omfatter methylenphosphinsyre - Google Patents

Peptidforbindelsesenhed, der omfatter methylenphosphinsyre

Info

Publication number
DK0629210T3
DK0629210T3 DK93903068T DK93903068T DK0629210T3 DK 0629210 T3 DK0629210 T3 DK 0629210T3 DK 93903068 T DK93903068 T DK 93903068T DK 93903068 T DK93903068 T DK 93903068T DK 0629210 T3 DK0629210 T3 DK 0629210T3
Authority
DK
Denmark
Prior art keywords
peptide
pct
linkage
aspartic proteinase
methylene
Prior art date
Application number
DK93903068T
Other languages
Danish (da)
English (en)
Inventor
Kim D Janda
Peter Wirsching
Shoji Ikeda
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK0629210T3 publication Critical patent/DK0629210T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3241—Esters of arylalkanephosphinic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
    • B60W40/00—Estimation or calculation of non-directly measurable driving parameters for road vehicle drive control systems not related to the control of a particular sub unit, e.g. by using mathematical models
    • B60W40/08—Estimation or calculation of non-directly measurable driving parameters for road vehicle drive control systems not related to the control of a particular sub unit, e.g. by using mathematical models related to drivers or passengers
    • B60W40/09—Driving style or behaviour
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H59/00—Control inputs to control units of change-speed-, or reversing-gearings for conveying rotary motion
    • F16H2059/003—Detecting or using driving style of a driver, e.g. for adapting shift schedules
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16H—GEARING
    • F16H2312/00—Driving activities
    • F16H2312/02—Driving off

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK93903068T 1992-01-09 1993-01-11 Peptidforbindelsesenhed, der omfatter methylenphosphinsyre DK0629210T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81935692A 1992-01-09 1992-01-09
PCT/US1993/000228 WO1993014114A1 (fr) 1992-01-09 1993-01-11 Unite de liaison peptidique comprenant de l'acide phosphinique et du methylene

Publications (1)

Publication Number Publication Date
DK0629210T3 true DK0629210T3 (da) 1998-10-12

Family

ID=25227921

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93903068T DK0629210T3 (da) 1992-01-09 1993-01-11 Peptidforbindelsesenhed, der omfatter methylenphosphinsyre

Country Status (12)

Country Link
US (1) US5563121A (fr)
EP (1) EP0629210B1 (fr)
JP (1) JP3547432B2 (fr)
AT (1) ATE167194T1 (fr)
AU (1) AU677949B2 (fr)
CA (1) CA2127295A1 (fr)
DE (1) DE69319101T2 (fr)
DK (1) DK0629210T3 (fr)
ES (1) ES2119888T3 (fr)
FI (1) FI943282A (fr)
NO (1) NO310919B1 (fr)
WO (1) WO1993014114A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004078780A1 (fr) * 2003-03-04 2004-09-16 Pepharm R&D Limited Composition pharmaceutique contenant l-seryl-l-leucine
CN103525794A (zh) * 2012-07-06 2014-01-22 天津市国际生物医药联合研究院 在原核系统中分离纯化包涵体形式hiv-1蛋白酶的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH634968A5 (de) * 1977-04-01 1983-03-15 Ciba Geigy Ag Herbizides und pflanzenwuchsregulierendes mittel enthaltend eine neue phosphinsaeure oder deren salze, ester, amide oder hydrazide sowie verwendung derselben.
ES2110404T3 (es) * 1989-12-16 1998-02-16 Hoechst Ag Inhibidores de proteasas retrovirales.

Also Published As

Publication number Publication date
FI943282A0 (fi) 1994-07-08
FI943282A (fi) 1994-09-08
JP3547432B2 (ja) 2004-07-28
AU677949B2 (en) 1997-05-15
EP0629210A1 (fr) 1994-12-21
AU3441893A (en) 1993-08-03
ES2119888T3 (es) 1998-10-16
DE69319101D1 (de) 1998-07-16
DE69319101T2 (de) 1998-11-05
CA2127295A1 (fr) 1993-07-22
NO310919B1 (no) 2001-09-17
NO942544L (no) 1994-08-19
NO942544D0 (no) 1994-07-06
US5563121A (en) 1996-10-08
ATE167194T1 (de) 1998-06-15
WO1993014114A1 (fr) 1993-07-22
EP0629210B1 (fr) 1998-06-10
JPH07503013A (ja) 1995-03-30

Similar Documents

Publication Publication Date Title
DE60045005D1 (de) Inhibitoren des memapsin 2 und ihre verwendung
EP0387231A3 (fr) Inhibiteurs des protéases rétro-virales
ES8305306A1 (es) Procedimiento para preparar isosteros de polipeptidos inhibi dores de renina.
EP0104041A1 (fr) Inhibiteurs d'enzyme
ATE377006T1 (de) Aus d-aminosäuren abgeleitete cystein- und serinproteasehemmer
WO1995034538A3 (fr) Purification de proteases serines, et leurs inhibiteurs synthetiques
Folk 2 Carboxypeptidase B
ATE279432T1 (de) Kininogen-inhibitoren
EP0498784A3 (en) Inhibitors of retroviral protease
ES2153433T3 (es) Inhibidores de trombina bivalentes.
DK0629210T3 (da) Peptidforbindelsesenhed, der omfatter methylenphosphinsyre
FI956055A (fi) Tekijä VII:sta johdettuja peptidejä
Enenkel et al. Specificity of chymotrypsin B toward glucagon
Nomura Specificity of prolyl endopeptidase
MX9503070A (es) Sistema de expresion que utiliza proteinas de fusion autolisables y un polipeptido de reduccion novedoso.
EP0837074A3 (fr) Fragment de fibronectine biologiquement actif en tant qu'inhibiteur de métastase cancéreuse
GB2262528B (en) Further improvements relating to the radiolabelling of proteins
WO1999001567A3 (fr) Methodes et compositions d'obtention d'une enzyme de desubiquitination et de ses variantes
Yonezawa et al. Substrate specificity of honeydew melon protease D, a plant serine endopeptidase
NZ333390A (en) Boron-containing peptides and bifunctional serine protease inhibitors
Zimmerman Role of proteinases from leukocytes in inflammation
MX9709921A (es) Alfa-d-galactosidasas de glicina y phaseolus.
TH33452B (th) ตัวผันแปรของอะโปรทินินที่มีคุณสมบัติที่ถูกปรับปรุง
ZA851832B (en) Renin inhibitors containing statine or derivatives thereof