DK0625517T3 - Taxan med antitumoraktivitet - Google Patents

Taxan med antitumoraktivitet

Info

Publication number
DK0625517T3
DK0625517T3 DK93111366T DK93111366T DK0625517T3 DK 0625517 T3 DK0625517 T3 DK 0625517T3 DK 93111366 T DK93111366 T DK 93111366T DK 93111366 T DK93111366 T DK 93111366T DK 0625517 T3 DK0625517 T3 DK 0625517T3
Authority
DK
Denmark
Prior art keywords
taxa
tumor activity
adriamicine
isolatable
endowed
Prior art date
Application number
DK93111366T
Other languages
Danish (da)
English (en)
Inventor
Ezio Bombardelli
Bruno Gabetta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK0625517T3 publication Critical patent/DK0625517T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK93111366T 1993-05-20 1993-07-15 Taxan med antitumoraktivitet DK0625517T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930334A IT1261667B (it) 1993-05-20 1993-05-20 Tassano ad attivita' antitumorale.

Publications (1)

Publication Number Publication Date
DK0625517T3 true DK0625517T3 (da) 1999-08-23

Family

ID=11401772

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93111366T DK0625517T3 (da) 1993-05-20 1993-07-15 Taxan med antitumoraktivitet

Country Status (22)

Country Link
US (1) US5407674A (no)
EP (1) EP0625517B1 (no)
JP (1) JPH07509259A (no)
KR (1) KR100315495B1 (no)
CN (1) CN1054381C (no)
AT (1) ATE174595T1 (no)
AU (1) AU6795194A (no)
CA (1) CA2140519A1 (no)
CZ (1) CZ286959B6 (no)
DE (2) DE69322619T2 (no)
DK (1) DK0625517T3 (no)
ES (1) ES2068166T3 (no)
FI (1) FI950207A (no)
GR (1) GR950300009T1 (no)
HK (1) HK1012628A1 (no)
HU (1) HU221503B (no)
IT (1) IT1261667B (no)
NO (1) NO310510B1 (no)
PL (1) PL178363B1 (no)
RU (1) RU2129551C1 (no)
SK (1) SK280873B6 (no)
WO (1) WO1994027984A1 (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4139993A1 (de) * 1991-12-04 1993-06-09 Merck Patent Gmbh, 6100 Darmstadt, De Pigmentzubereitung
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
US5756536A (en) * 1995-11-03 1998-05-26 Purdue Research Foundation Microbial transformation of taxol and cephalomannine
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
CA2188190A1 (en) 1996-10-18 1998-04-18 Sarala Balachandran The semi-synthesis of a protected bacatin iii compound
US6410756B1 (en) 1996-10-24 2002-06-25 Institut National De La Recherche Scientifique Family of Canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
GEP20043239B (en) 2000-02-02 2004-05-25 Florida State Univ Research Foundation Us C10 Carbonate Substituted Taxanes as Antitumor Agents
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
HN2005000054A (es) * 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
US7169307B2 (en) * 2004-09-02 2007-01-30 Jian Liu Process for the extraction of paclitaxel and 9-dihydro-13-acetylbaccatin III from Taxus
MX2007009748A (es) * 2005-02-14 2007-09-26 Univ Florida State Res Found Composiciones de taxano sustituidas con esteres ciclopropilicos en c10.
JP4954983B2 (ja) 2005-05-18 2012-06-20 ファーマサイエンス・インコーポレイテッド Ｂｉｒドメイン結合化合物
US9127208B2 (en) * 2006-04-03 2015-09-08 Pharmatherm Chemicals, Inc. Thermal extraction method and product
WO2007131366A1 (en) 2006-05-16 2007-11-22 Aegera Therapeutics Inc. Iap bir domain binding compounds
US7905990B2 (en) * 2007-11-20 2011-03-15 Ensyn Renewables, Inc. Rapid thermal conversion of biomass
DK2080764T3 (da) 2008-01-18 2012-09-24 Indena Spa Faste former af ortataxel
US8242166B2 (en) * 2008-03-31 2012-08-14 Florida State University Research Foundation, Inc. C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes
AU2011214057B2 (en) 2010-02-12 2016-11-17 Pharmascience Inc. IAP BIR domain binding compounds
US20110284359A1 (en) 2010-05-20 2011-11-24 Uop Llc Processes for controlling afterburn in a reheater and for controlling loss of entrained solid particles in combustion product flue gas
US8499702B2 (en) 2010-07-15 2013-08-06 Ensyn Renewables, Inc. Char-handling processes in a pyrolysis system
US9441887B2 (en) 2011-02-22 2016-09-13 Ensyn Renewables, Inc. Heat removal and recovery in biomass pyrolysis
US9347005B2 (en) 2011-09-13 2016-05-24 Ensyn Renewables, Inc. Methods and apparatuses for rapid thermal processing of carbonaceous material
US10400175B2 (en) 2011-09-22 2019-09-03 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US10041667B2 (en) 2011-09-22 2018-08-07 Ensyn Renewables, Inc. Apparatuses for controlling heat for rapid thermal processing of carbonaceous material and methods for the same
US9044727B2 (en) 2011-09-22 2015-06-02 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US9109177B2 (en) 2011-12-12 2015-08-18 Ensyn Renewables, Inc. Systems and methods for renewable fuel
US9670413B2 (en) 2012-06-28 2017-06-06 Ensyn Renewables, Inc. Methods and apparatuses for thermally converting biomass
US10633606B2 (en) 2012-12-10 2020-04-28 Ensyn Renewables, Inc. Systems and methods for renewable fuel
CA2995845A1 (en) 2015-08-21 2017-03-02 Ensyn Renewables, Inc. Liquid biomass heating system
BR112019013387B1 (pt) 2016-12-29 2023-03-28 Ensyn Renewables, Inc Desmetalização de biomassa

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206221A (en) * 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
US5157049A (en) * 1988-03-07 1992-10-20 The United States Of America As Represented By The Department Of Health & Human Services Method of treating cancers sensitive to treatment with water soluble derivatives of taxol
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
IT1254515B (it) * 1992-03-06 1995-09-25 Indena Spa Tassani di interesse oncologico, loro metodo di preparazione ed uso
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol

Also Published As

Publication number Publication date
CZ12295A3 (en) 1995-09-13
US5407674A (en) 1995-04-18
EP0625517B1 (en) 1998-12-16
RU2129551C1 (ru) 1999-04-27
RU95105981A (ru) 1996-10-27
IT1261667B (it) 1996-05-29
GR950300009T1 (en) 1995-03-31
CZ286959B6 (en) 2000-08-16
PL178363B1 (pl) 2000-04-28
SK6095A3 (en) 1995-07-11
DE69322619D1 (de) 1999-01-28
ES2068166T1 (es) 1995-04-16
NO950184L (no) 1995-01-18
AU6795194A (en) 1994-12-20
HU221503B (en) 2002-10-28
FI950207A0 (fi) 1995-01-18
FI950207A (fi) 1995-01-18
PL307089A1 (en) 1995-05-02
KR100315495B1 (ko) 2002-06-20
CN1054381C (zh) 2000-07-12
JPH07509259A (ja) 1995-10-12
HK1012628A1 (en) 1999-08-06
NO950184D0 (no) 1995-01-18
ITRM930334A0 (it) 1993-05-20
NO310510B1 (no) 2001-07-16
HUT72607A (en) 1996-05-28
WO1994027984A1 (en) 1994-12-08
DE625517T1 (de) 1995-07-13
ITRM930334A1 (it) 1994-11-20
DE69322619T2 (de) 1999-06-24
SK280873B6 (sk) 2000-08-14
EP0625517A1 (en) 1994-11-23
CA2140519A1 (en) 1994-12-08
HU9500152D0 (en) 1995-03-28
ATE174595T1 (de) 1999-01-15
ES2068166T3 (es) 1999-03-01
CN1110055A (zh) 1995-10-11

Similar Documents

Publication Publication Date Title
DK0625517T3 (da) Taxan med antitumoraktivitet
CA2130745A1 (en) Enhanced production of taxol and taxanes by cell cultures of taxus species
FI970271A (fi) Puolisynteettiset taksaanit, joilla on kasvaimenvastainen vaikutus
NO930773L (no) Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel
RU93004623A (ru) Производные таксана iii, способы их получения
ATE295363T1 (de) Beta-laktame zur herstellung von taxanen mit furyl oder thienyl substituierter seitenkette
RU93004649A (ru) Производные таксана, способ их получения и использование в онкологии,фармкомпозиция
ATE225340T1 (de) Einschlusskomplexe von taxol oder taxotere oder taxus-extrakten und cyclodextrinen, ihre herstellung und ihre verwendung
FI844225A0 (fi) Griseolinsyraderivat och deras anvaendning.
BR0008633A (pt) Processo para a preparação de taxanos partindode 10-desacetilbaccatin iii
DE69430797D1 (de) C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen
HUP9700991A2 (hu) Taxoidszármazékok és eljárás előállításukra
TR200000185T2 (tr) Kontrollü aktif madde yayılımına sahip bitki koruyucu granülat.
BG70355A (bg) Хербицидно средство
FI912964A (fi) Enantiomerer av 2 -tetrahydrofuranderivat, mellanprodukter daerav och deras framstaellning.
KR920000688A (ko) 벤질 케톤 및 그를 함유하는 살진균제
RU92002542A (ru) 2,2-диметил-4,5-нафто-1,3-диоксолан в качестве регулятора роста и развития растений
IT1274356B (it) Tassani semisintetici odtati di attivita' antitumorale